Innovations in Electrophysiology

Dissociated cell cultures, cortex

Bourke JL, Quigley AF, Duchi S, O'Connell CD, Crook JM, Wallace GG, Cook MJ, Kapsa RMI (2017) Three-dimensional neural cultures produce networks that mimic native brain activity. Journal of Tissue Engineering and Regenerative Medicine:n/a-n/a.

Dermutz H, Thompson-Steckel G, Forro C, de Lange V, Dorwling-Carter L, Voros J, Demko L (2017) Paper-based patterned 3D neural cultures as a tool to study network activity on multielectrode arrays. RSC Advances 7:39359-39371.

Fedorovich S, Hofmeijer J, van Putten MJ, le Feber J (2017) Reduced Synaptic Vesicle Recycling during Hypoxia in Cultured Cortical Neurons. Front Cell Neurosci 11:32.

Gertz ML, Baker Z, Jose S, Peixoto N (2017) Time-dependent Increase in the Network Response to the Stimulation of Neuronal Cell Cultures on Micro-electrode Arrays.e55726.

Kuykendal M, Guvanasen G, Potter S, Grover M, DeWeerth S (2017) Closed-Loop Characterization of Neuronal Activation Using Electrical Stimulation and Optical Imaging. Processes 5:30.

Kuykendal M, Potter S, Grover M, DeWeerth S (2017) Targeted Stimulation Using Differences in Activation Probability across the Strength–Duration Space. Processes 5:14.

le Feber J, Erkamp N, van Putten M, Hofmeijer J (2017) Loss and recovery of functional connectivity in cultured cortical networks exposed to hypoxia. J Neurophysiol 118:394-403.

Mack CM, Hall DR, Herr DW, Shafer TJ (2017) Low and High-Frequency Field Potentials in Cortical Networks Exhibit Distinct Responses to Chemicals. The FASEB Journal 31:861.814.

Okujeni S, Kandler S, Egert U (2017) Mesoscale architecture shapes initiation and richness of spontaneous network activity. J Neurosci.

Orenstein O, Keren H (2017) Development of Cortical Networks under Continuous Stimulation. Front Mol Neurosci 10:18.

Pasquale V, Martinoia S, Chiappalone M (2017) Stimulation triggers endogenous activity patterns in cultured cortical networks. Sci Rep 7:9080.

Pérez-Gómez A, Cabrera-García D, Warm D, Marini AM, Salas Puig J, Fernández-Sánchez MT, Novelli A (2017) Selective Enhancement of Domoic Acid Toxicity in Primary Cultures of Cerebellar Granule Cells by Lowering Extracellular Na+ Concentration. Toxicological Sciences:kfx201-kfx201.

Satuvuori E, Mulansky M, Bozanic N, Malvestio I, Zeldenrust F, Lenk K, Kreuz T (2017) Measures of spike train synchrony for data with multiple time scales. J Neurosci Methods 287:25-38.

Scarsi F, Tessadori J, Chiappalone M, Pasquale V (2017) Investigating the impact of electrical stimulation temporal distribution on cortical network responses. BMC Neurosci 18:49.

Simon DM, Charkhkar H, St John C, Rajendran S, Kang T, Reit R, Arreaga-Salas D, McHail DG, Knaack GL, Sloan A, Grasse D, Dumas TC, Rennaker RL, Pancrazio JJ, Voit WE (2017) Design and demonstration of an intracortical probe technology with tunable modulus. J Biomed Mater Res A 105:159-168.

Ugbode CI, Smith I, Whalley BJ, Hirst WD, Rattray M (2017) Sonic hedgehog signalling mediates astrocyte crosstalk with neurons to confer neuroprotection. J Neurochem 142:429-443.

Valkki IA, Lenk K, Mikkonen JE, Kapucu FE, Hyttinen JAK (2017) Network-Wide Adaptive Burst Detection Depicts Neuronal Activity with Improved Accuracy. Front Comput Neurosci 11:40.

Vardi R, Goldental A, Sheinin A, Sardi S, Kanter I (2017) Fast reversible learning based on neurons functioning as anisotropic multiplex hubs. EPL (Europhysics Letters) 118:46002.

Vassallo A, Chiappalone M, De Camargos Lopes R, Scelfo B, Novellino A, Defranchi E, Palosaari T, Weisschu T, Ramirez T, Martinoia S, Johnstone AFM, Mack CM, Landsiedel R, Whelan M, Bal-Price A, Shafer TJ (2017) A multi-laboratory evaluation of microelectrode array-based measurements of neural network activity for acute neurotoxicity testing. Neurotoxicology 60:280-292.

Bart Martens M, Frega M, Classen J, Epping L, Bijvank E, Benevento M, van Bokhoven H, Tiesinga P, Schubert D, Nadif Kasri N (2016) Euchromatin histone methyltransferase 1 regulates cortical neuronal network development. Sci Rep 6:35756.

Barykina NV, Subach OM, Doronin DA, Sotskov VP, Roshchina MA, Kunitsyna TA, Malyshev AY, Smirnov IV, Azieva AM, Sokolov IS, Piatkevich KD, Burtsev MS, Varizhuk AM, Pozmogova GE, Anokhin KV, Subach FV, Enikolopov GN (2016) A new design for a green calcium indicator with a smaller size and a reduced number of calcium-binding sites. Sci Rep 6:34447.

Berglund K, Tung JK, Higashikubo B, Gross RE, Moore CI, Hochgeschwender U (2016) Combined Optogenetic and Chemogenetic Control of Neurons. Methods Mol Biol 1408:207-225.

Blanquie O, Liebmann L, Hubner CA, Luhmann HJ, Sinning A (2016) NKCC1-Mediated GABAergic Signaling Promotes Postnatal Cell Death in Neocortical Cajal-Retzius Cells. Cereb Cortex.

Caputo L, Souza LF, Alloisio S, Cornara L, De Feo V (2016) Coriandrum sativum and Lavandula angustifolia Essential Oils: Chemical Composition and Activity on Central Nervous System. Int J Mol Sci 17.

Dvorkin R, Ziv NE (2016) Relative Contributions of Specific Activity Histories and Spontaneous Processes to Size Remodeling of Glutamatergic Synapses. PLoS Biol 14:e1002572.

Hasan F, Berdichevsky Y (2016) Neural Circuits on a Chip. Micromachines 7.

Huang Y, Chang Y, Chen C, Lai P, Chan CK (2016) Positive Feedback and Synchronized Bursts in Neuronal

Cultures. In: arXiv.

Kapucu FE, Valkki I, Mikkonen JE, Leone C, Lenk K, Tanskanen JM, Hyttinen JA (2016) Spectral Entropy Based Neuronal Network Synchronization Analysis Based on Microelectrode Array Measurements. Front Comput Neurosci 10:112.

Keren H, Marom S (2016) Long-range synchrony and emergence of neural reentry. Sci Rep 6:36837.

Knudsen AM (2016) NTNU Cyborg: A study into embodying Neuronal Cultures through Robotic Systems. Department of Engineering Cybernetics.

Kumar SS, Wulfing J, Okujeni S, Boedecker J, Riedmiller M, Egert U (2016) Autonomous Optimization of Targeted Stimulation of Neuronal Networks. PLoS Comput Biol 12:e1005054.

Latifi S, Tamayol A, Habibey R, Sabzevari R, Kahn C, Geny D, Eftekharpour E, Annabi N, Blau A, Linder M, Arab-Tehrany E (2016) Natural lecithin promotes neural network complexity and activity. Sci Rep 6:25777.

Martens MB, Frega M, Classen J, Epping L, Bijvank E, Benevento M, van Bokhoven H, Tiesinga P, Schubert D, Nadif Kasri N (2016) Euchromatin histone methyltransferase 1 regulates cortical neuronal network development. Sci Rep 6:35756.

Perez-Alcazar M, Culley G, Lyckenvik T, Mobarrez K, Bjorefeldt A, Wasling P, Seth H, Asztely F, Harrer A, Iglseder B, Aigner L, Hanse E, Illes S (2016) Human Cerebrospinal Fluid Promotes Neuronal Viability and Activity of Hippocampal Neuronal Circuits In Vitro. Front Cell Neurosci 10:54.

Pigareva Y, Malishev E, Gladkov A, Kolpakov V, Bukatin A, Mukhina I, Kazantsev V, Pimashkin A (2016) Neural signal registration and analysis of axons grown in microchannels. Journal of Physics: Conference Series 741.

Poon VY, Gu M, Ji F, VanDongen AM, Fivaz M (2016) miR-27b shapes the presynaptic transcriptome and influences neurotransmission by silencing the polycomb group protein Bmi1. BMC Genomics 17:777.

Pulizzi R, Musumeci G, Van den Haute C, Van De Vijver S, Baekelandt V, Giugliano M (2016) Brief wide-field photostimuli evoke and modulate oscillatory reverberating activity in cortical networks. Sci Rep 6:24701.

Ryu JR, Jang MJ, Jo Y, Joo S, Lee do H, Lee BY, Nam Y, Sun W (2016) Synaptic compartmentalization by micropatterned masking of a surface adhesive cue in cultured neurons. Biomaterials 92:46-56.

Sardi S, Goldental A, Amir H, Vardi R, Kanter I (2016) Vitality of Neural Networks under Reoccurring Catastrophic Failures. Sci Rep 6:31674.

Shaukat A, Thivierge JP (2016) Statistical Evaluation of Waveform Collapse Reveals Scale-Free Properties of Neuronal Avalanches. Front Comput Neurosci 10:29.

Shein-Idelson M, Cohen G, Ben-Jacob E, Hanein Y (2016) Modularity Induced Gating and Delays in Neuronal Networks. PLoS Comput Biol 12:e1004883.

Vardi R, Goldental A, Sardi S, Sheinin A, Kanter I (2016) Simultaneous multi-patch-clamp and extracellular-array recordings: Single neuron reflects network activity. Sci Rep 6:36228.

Wanke E, Gullo F, Dossi E, Valenza G, Becchetti A (2016) Neuron-glia crosstalk revealed in reverberating networks by simultaneous extracellular recording of spikes and astrocytes' glutamate transporter and K+ currents. J Neurophysiol:jn 00509 02016.

Wijdenes P, Ali H, Armstrong R, Zaidi W, Dalton C, Syed NI (2016) A novel bio-mimicking, planar nano-edge microelectrode enables enhanced long-term neural recording. Sci Rep 6:34553.

Wilk N, Habibey R, Golabchi A, Latifi S, Ingebrandt S, Blau A (2016) Selective comparison of gelling agents as neural cell culture matrices for long-term microelectrode array electrophysiology. OCL 23.

Afshar G, El Hady A, Geisel T, Stuehmer W, Wolf F (2015) Enhancing burst activation and propagation in cultured neuronal networks by photo-stimulation. bioRxiv.

Bartsch H, Himmerlich M, Fischer M, Demkó L, Hyttinen J, Schober A (2015) LTCC-Based Multi-Electrode Arrays for 3D in Vitro Cell Cultures. Journal of Ceramic Science and Technology 6:315-324.

Charlesworth P, Cotterill E, Morton A, Grant SG, Eglen SJ (2015) Quantitative differences in developmental profiles of spontaneous activity in cortical and hippocampal cultures. Neural Dev 10:1.

Charlesworth P, Morton A, Eglen SJ, Komiyama NH, Grant SG (2015) Canalization of genetic and pharmacological perturbations in developing primary neuronal activity patterns. Neuropharmacology 100:47-55.

Dranias MR, Westover MB, Cash S, VanDongen AM (2015) Stimulus information stored in lasting active and hidden network states is destroyed by network bursts. Front Integr Neurosci 9:14.

Farah N, Levinsky A, Brosh I, kahn I, Shoam S (2015) Holographic fiber bundle system for patterned optogenetic activation of large-scale neuronal networks. Neurophotonics 2.

Goldental A, Sabo P, Sardi S, Vardi R, Kanter I (2015) Mimicking Collective Firing Patterns of Hundreds of Connected Neurons using a Single-Neuron Experiment. Front Neurosci 9:508.

Goldental A, Vardi R, Sardi S, Sabo P, Kanter I (2015) Broadband macroscopic cortical oscillations emerge from intrinsic neuronal response failures. Front Neural Circuits 9:65.

Hamilton F, Graham R, Luu L, Peixoto N (2015) Time-Dependent Increase in Network Response to Stimulation. PLoS ONE 10:e0142399.

Haroush N, Marom S (2015) Slow dynamics in features of synchronized neural network responses. Front Comput Neurosci 9:40.

Ju H, Dranias MR, Banumurthy G, VanDongen AM (2015) Spatiotemporal memory is an intrinsic property of networks of dissociated cortical neurons. J Neurosci 35:4040-4051.

Kanner S, Bisio M, Cohen G, Goldin M, Tedesco M, Hanein Y, Ben-Jacob E, Barzilai A, Chiappalone M, Bonifazi P (2015) Design, Surface Treatment, Cellular Plating, and Culturing of Modular Neuronal Networks Composed of Functionally Inter-connected Circuits.e52572.

Kuebler ES, Tauskela JS, Aylsworth A, Zhao X, Thivierge JP (2015) Burst predicting neurons survive an in vitro glutamate injury model of cerebral ischemia. Sci Rep 5:17718.

Li Y, Li H, Wang Y (2015) A Multichannel Waveform Generator for Spatiotemporal Stimulation of Dissociated Neuronal Network on MEA Journal of Medical and Bioengineering 4.

Lu C, Chen Q, Zhou T, Bozic D, Fu Z, Pan JQ, Feng G (2015) Micro-electrode array recordings reveal reductions in both excitation and inhibition in cultured cortical neuron networks lacking Shank3. Mol Psychiatry.

Newman JP, Fong MF, Millard DC, Whitmire CJ, Stanley GB, Potter SM (2015) Optogenetic feedback control of neural activity. Elife 4:e07192.

Peelaerts W, Bousset L, Van der Perren A, Moskalyuk A, Pulizzi R, Giugliano M, Van den Haute C, Melki R, Baekelandt V (2015) alpha-Synuclein strains cause distinct synucleinopathies after local and systemic administration. Nature 522:340-344.

Pirino V, Riccomagno E, Martinoia S, Massobrio P (2015) A topological study of repetitive co-activation networks in in vitro cortical assemblies. Phys Biol 12:016007.

Smith I, Haag M, Ugbode C, Tams D, Rattray M, Przyborski S, Bithell A, Whalley BJ (2015) Neuronal-glial populations form functional networks in a biocompatible 3D scaffold. Neurosci Lett 609:198-202.

Vardi R, Goldental A, Marmari H, Brama H, Stern EA, Sardi S, Sabo P, Kanter I (2015) Neuronal Response Impedance Mechanism Implementing Cooperative Networks with Low Firing Rates and Microsecond Precision. Frontiers in Neural Circuits 9.

Charkhkar H, Frewin C, Nezafati M, Knaack GL, Peixoto N, Saddow SE, Pancrazio JJ (2014) Use of cortical neuronal networks for in vitro material biocompatibility testing. Biosens Bioelectron 53:316-323.

Goldental A, Guberman S, Vardi R, Kanter I (2014) A computational paradigm for dynamic logic-gates in neuronal activity. Front Comput Neurosci 8:52.

Gullo F, Amadeo A, Donvito G, Lecchi M, Costa B, Constanti A, Wanke E (2014) Atypical "seizure-like" activity in cortical reverberating networks in vitro can be caused by LPS-induced inflammation: a multi-electrode array study from a hundred neurons. Front Cell Neurosci 8:361.

Gullo F, Manfredi I, Lecchi M, Casari G, Wanke E, Becchetti A (2014) Multi-electrode array study of neuronal cultures expressing nicotinic beta2-V287L subunits, linked to autosomal dominant nocturnal frontal lobe epilepsy. An in vitro model of spontaneous epilepsy. Front Neural Circuits 8:87.

Hagar M, Roni V, Ido K (2014) Chaotic and non-chaotic phases in experimental responses of a single neuron. EPL (Europhysics Letters) 106:46002.

Hedrich UB, Liautard C, Kirschenbaum D, Pofahl M, Lavigne J, Liu Y, Theiss S, Slotta J, Escayg A, Dihne M, Beck H, Mantegazza M, Lerche H (2014) Impaired Action Potential Initiation in GABAergic Interneurons Causes Hyperexcitable Networks in an Epileptic Mouse Model Carrying a Human NaV1.1 Mutation. J Neurosci 34:14874-14889.

Keren H, Marom S (2014) Controlling neural network responsiveness: tradeoffs and constraints. Front Neuroeng 7:11.

le Feber J, Stoyanova, II, Chiappalone M (2014) Connectivity, excitability and activity patterns in neuronal networks. Phys Biol 11:036005.

Martens MB, Chiappalone M, Schubert D, Tiesinga PH (2014) Separating burst from background spikes in multichannel neuronal recordings using return map analysis. Int J Neural Syst 24:1450012.

Napoli A, Xie J, Obeid I (2014) Understanding the temporal evolution of neuronal connectivity in cultured networks using statistical analysis. BMC Neurosci 15:17.

Stoyanova, II, le Feber J (2014) Ghrelin accelerates synapse formation and activity development in cultured cortical networks. BMC Neurosci 15:49.

Vardi R, Marmari H, Kanter I (2014) Error correction and fast detectors implemented by ultrafast neuronal plasticity. Phys Rev E 89.

Weir K, Blanquie O, Kilb W, Luhmann HJ, Sinning A (2014) Comparison of spike parameters from optically identified GABAergic and glutamatergic neurons in sparse cortical cultures. Front Cell Neurosci 8:460.

Dranias MR, Ju H, Rajaram E, Vandongen AM (2013) Short-term memory in networks of dissociated cortical neurons. J Neurosci 33:1940-1953.

Hammond MW, Xydas D, Downes JH, Bucci G, Becerra V, Warwick K, Constanti A, Nasuto SJ, Whalley BJ (2013) Endogenous cholinergic tone modulates spontaneous network level neuronal activity in primary cortical cultures grown on multi-electrode arrays. BMC Neurosci 14:38.

Jantzen SU, Ferrea S, Wach C, Quasthoff K, Illes S, Scherfeld D, Hartung HP, Seitz RJ, Dihne M (2013) In vitro neuronal network activity in NMDA receptor encephalitis. BMC Neurosci 14:17.

Kiiski H, Aanismaa R, Tenhunen J, Hagman S, Yla-Outinen L, Aho A, Yli-Hankala A, Bendel S, Skottman H, Narkilahti S (2013) Healthy human CSF promotes glial differentiation of hESC-derived neural cells while retaining spontaneous activity in existing neuronal networks. Biol Open 2:605-612.

Lavi A, Sheinin A, Shapira R, Zelmanoff D, Ashery U (2013) DOC2B and Munc13-1 Differentially Regulate Neuronal Network Activity. Cereb Cortex.

Mack CM, Lin B, Turner JD, Johnstone AF, Burgoon LD, Shafer TJ (2013) Burst and principal components analyses of mea data for 16 chemicals describe at least three effects classes. Neurotoxicology.

Moretti D, Garenne A, Haro E, Poulletierde Gannes F, Lagroye I, Leveque P, Veyret B, Lewis N (2013) InVitro Exposureof Neuronal Networkstoa GSM-1800 Signal. Bioelectromagnetics.

Nimmervoll B, White R, Yang JW, An S, Henn C, Sun JJ, Luhmann HJ (2013) LPS-induced microglial secretion of TNFalpha increases activity-dependent neuronal apoptosis in the neonatal cerebral cortex. Cereb Cortex 23:1742-1755.

Pu J, Gong H, Li X, Luo Q (2013) Developing neuronal networks: self-organized criticality predicts the future. Sci Rep 3:1081.

Vardi R, Goldental A, Guberman S, Kalmanovich A, Marmari H, Kanter I (2013) Sudden synchrony leaps accompanied by frequency multiplications in neuronal activity. Front Neural Circuits 7:176.

Vardi R, Guberman S, Goldental A, Kanter I (2013) An experimental evidence-based computational paradigm for new logic-gates in neuronal activity. EPL (Europhysics Letters) 103.

Vardi R, Timor R, Marom S, Abeles M, Kanter I (2013) Synchronization by elastic neuronal latencies. Phys Rev E Stat Nonlin Soft Matter Phys 87:012724.

Vincent K, Tauskela JS, Mealing GA, Thivierge JP (2013) Altered network communication following a neuroprotective drug treatment. PLoS ONE 8:e54478.

Weihberger O, Okujeni S, Mikkonen JE, Egert U (2013) Quantitative examination of stimulus-response relations in cortical networks in vitro. J Neurophysiol 109:1764-1774.

Albrecht P, Bouchachia I, Goebels N, Henke N, Hofstetter HH, Issberner A, Kovacs Z, Lewerenz J, Lisak D, Maher P, Mausberg AK, Quasthoff K, Zimmermann C, Hartung HP, Methner A (2012) Effects of dimethyl fumarate on neuroprotection and immunomodulation. J Neuroinflammation 9:163.

Becchetti A, Gullo F, Bruno G, Dossi E, Lecchi M, Wanke E (2012) Exact distinction of excitatory and inhibitory neurons in neural networks: a study with GFP-GAD67 neurons optically and electrophysiologically recognized on multielectrode arrays. Front Neural Circuits 6:63.

Biffi E, Piraino F, Pedrocchi A, Fiore GB, Ferrigno G, Redaelli A, Menegon A, Rasponi M (2012) A microfluidic platform for controlled biochemical stimulation of twin neuronal networks. Biomicrofluidics 6:24106-2410610.

Gullo F, Maffezzoli A, Dossi E, Lecchi M, Wanke E (2012) Classifying heterogeneity of spontaneous up-states: a method for revealing variations in firing probability, engaged neurons and Fano factor. J Neurosci Methods 203:407-417.

Hales CM, Zeller-Townson R, Newman JP, Shoemaker JT, Killian NJ, Potter SM (2012) Stimulus-evoked high frequency oscillations are present in neuronal networks on microelectrode arrays. Front Neural Circuits 6:29.

Hinard V, Mikhail C, Pradervand S, Curie T, Houtkooper RH, Auwerx J, Franken P, Tafti M (2012) Key electrophysiological, molecular, and metabolic signatures of sleep and wakefulness revealed in primary cortical cultures. J Neurosci 32:12506-12517.

Kanagasabapathi TT, Massobrio P, Barone RA, Tedesco M, Martinoia S, Wadman WJ, Decre MM (2012) Functional connectivity and dynamics of cortical-thalamic networks co-cultured in a dual compartment device. J Neural Eng 9:036010.

Kapucu FE, Tanskanen JM, Mikkonen JE, Yla-Outinen L, Narkilahti S, Hyttinen JA (2012) Burst analysis tool for developing neuronal networks exhibiting highly varying action potential dynamics. Front Comput Neurosci 6:38.

Kaufman M, Corner MA, Ziv NE (2012) Long-term Relationships between Cholinergic Tone, Synchronous Bursting and Synaptic Remodeling. PLoS ONE 7:e40980.

Levy O, Ziv NE, Marom S (2012) Enhancement of neural representation capacity by modular architecture in networks of cortical neurons. Eur J Neurosci 35:1753-1760.

Marconi E, Nieus T, Maccione A, Valente P, Simi A, Messa M, Dante S, Baldelli P, Berdondini L, Benfenati F (2012) Emergent functional properties of neuronal networks with controlled topology. PLoS ONE 7:e34648.

Newman JP, Zeller-Townson R, Fong MF, Arcot Desai S, Gross RE, Potter SM (2012) Closed-Loop, Multichannel Experimentation Using the Open-Source NeuroRighter Electrophysiology Platform. Front Neural Circuits 6:98.

Schock SC, Jolin-Dahel KS, Schock PC, Theiss S, Arbuthnott GW, Garcia-Munoz M, Staines WA (2012) Development of dissociated cryopreserved rat cortical neurons in vitro. J Neurosci Methods 205:324-333.

Stephens CL, Toda H, Palmer TD, DeMarse TB, Ormerod BK (2012) Adult neural progenitor cells reactivate superbursting in mature neural networks. Exp Neurol 234:20-30.

van Drongelen W, Wildeman A, Radojicic M, Suresh J, Wang J, Marks J (2012) A Novel Technique to Evaluate Network Properties. In: Gordon Research Conference 2012, Mechanisms of Epilepsy & Neuronal Synchronization.

Vardi R, Wallach A, Kopelowitz E, Abeles M, Marom S, Kanter I (2012) Synthetic reverberating activity patterns embedded in networks of cortical neurons. EPL (Europhysics Letters) 97:66002.

Wallach A, Marom S (2012) Interactions between network synchrony and the dynamics of neuronal threshold. J Neurophysiol 107:2926-2936.

Zemianek JM, Serra M, Guaraldi M, Shea TB (2012) Stimulation with a low-amplitude, digitized synaptic signal to invoke robust activity within neuronal networks on multielectrode arrays. Biotechniques 52:177-182.

Zullo L, Chiappalone M, Martinoia S, Benfenati F (2012) A "spike-based" grammar underlies directional modification in network connectivity: effect on bursting activity and implications for bio-hybrids systems. PLoS ONE 7:e49299.

Baltz T, Herzog A, Voigt T (2011) Slow oscillating population activity in developing cortical networks: models and experimental results. J Neurophysiol 106:1500-1514.

Chevalier G, Suberbielle E, Monnet C, Duplan V, Martin-Blondel G, Farrugia F, Le Masson G, Liblau R, Gonzalez-Dunia D (2011) Neurons are MHC class I-dependent targets for CD8 T cells upon neurotropic viral infection. PLoS Pathog 7:e1002393.

Clifford MA, Kanwal JK, Dzakpasu R, Donoghue MJ (2011) EphA4 expression promotes network activity and spine maturation in cortical neuronal cultures. Neural Dev 6:21.

Defranchi E, Novellino A, Whelan M, Vogel SA, Ramirez-Hernandez T, Van Ravenzwaay B, Landsiedel R (2011) Feasibility assessment of Micro electrode chip assay (MEA) as a method of detecting neurotoxicity in vitro. Frontiers in Neuroengineering 4.

Difato F, Dal Maschio M, Marconi E, Ronzitti G, Maccione A, Fellin T, Berdondini L, Chieregatti E, Benfenati F, Blau A (2011) Combined optical tweezers and laser dissector for controlled ablation of functional connections in neural networks. J Biomed Opt 16:051306.

Ferrández JM, Lorente V, Garrigós J, Fernandez E (2011) Image Coding for Robotic Guidance Using Neuroblastoma Cultures. Majlesi Journal of Electrical Engineering 5.

Frega M, Pasquale V, Tedesco M, Marcoli M, Contestabile A, Nanni M, Bonzano L, Maura G, Chiappalone M (2011) Cortical cultures coupled to Micro-Electrode Arrays: A novel approach to perform in vitro excitotoxicity testing. Neurotoxicol Teratol.

Hogberg HT, Sobanski T, Novellino A, Whelan M, Weiss DG, Bal-Price AK (2011) Application of micro-electrode arrays (MEAs) as an emerging technology for developmental neurotoxicity: evaluation of domoic acid-induced effects in primary cultures of rat cortical neurons. Neurotoxicology 32:158-168.

Kanagasabapathi TT, Ciliberti D, Martinoia S, Wadman WJ, Decre MM (2011) Dual-compartment neurofluidic system for electrophysiological measurements in physically segregated and functionally connected neuronal cell culture. Front Neuroeng 4:13.

Levine-Small N, Yekutieli Z, Aljadeff Y, Boccaletti S, Ben Jacob E, Barzilai A (2011) Reduced Synchronization Persistence in Neural Networks derived from Atm-Deficient Mice. Frontiers in Neuroscience 5.

Novellino A, Scelfo B, Palosaari T, Price A, Sobanski T, Shafer TJ, Johnstone AFM, Gross GW, Gramowski A, Schroeder O, J?gelt K, Chiappalone M, Benfenati F, Martinoia S, Tedesco MT, Defranchi E, D'Angelo P, Whelan M (2011) Development of micro-electrode array based tests for neurotoxicity: assessment of interlaboratory reproducibility with neuroactive chemicals. Frontiers in Neuroengineering 4.

Ortman RL, Venayagamoorthy K, Potter SM (2011) Input Separability in Living Liquid State Machines. In: ICANNGA 2011, Part I, LNCS 6593 (Dobnikar A, Lotrič U, Šter B, eds), pp 220–229.

Pan L, Alagapan S, Franca E, Brewer GJ, Wheeler BC (2011) Propagation of action potential activity in a predefined microtunnel neural network. J Neural Eng 8:046031.

Piet R, Garenne A, Farrugia F, Le Masson G, Marsicano G, Chavis P, Manzoni OJ (2011) State-dependent, bidirectional modulation of neural network activity by endocannabinoids. J Neurosci 31:16591-16596.

Robinette BL, Harrill JA, Mundy WR, Shafer TJ (2011) In vitro assessment of developmental neurotoxicity: use of microelectrode arrays to measure functional changes in neuronal network ontogeny. Front Neuroengineering 4:1.

Scelfo B, Politi M, Reniero F, Zaldivar JM (2011) Application of multielectrode array (MEA) chips for studying the neurotoxicity of mixtures. In: JRC Scientific and Technical Reports: European Comission.

Shein-Idelson M, Ben-Jacob E, Hanein Y (2011) Engineered neuronal circuits: a new platform for studying the role of modular topology. Front Neuroeng 4:10.

Shew WL, Yang H, Yu S, Roy R, Plenz D (2011) Information capacity and transmission are maximized in balanced cortical networks with neuronal avalanches. J Neurosci 31:55-63.

Verpelli C, Dvoretskova E, Vicidomini C, Rossi F, Chiappalone M, Schoen M, Di Stefano B, Mantegazza R, Broccoli V, Boeckers TM, Dityatev A, Sala C (2011) Importance of shank3 in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapses. J Biol Chem.

Wallach A, Eytan D, Gal A, Zrenner C, Marom S (2011) Neuronal Response Clamp. Frontiers in Neuroengineering 4.

Xydas D, Downes JH, Spencer MC, Hammond MW, Nasuto SJ, Whalley BJ, Becerra VM, Warwick K (2011) Revealing ensemble state transition patterns in multi-electrode neuronal recordings using hidden Markov models. IEEE Trans Neural Syst Rehabil Eng 19:345-355.

Baltz T, de Lima AD, Voigt T (2010) Contribution of GABAergic interneurons to the development of spontaneous activity patterns in cultured neocortical networks. Front Cell Neurosci 4:15.

Biffi E, Ghezzi D, Pedrocchi A, Ferrigno G (2010) Development and validation of a spike detection and classification algorithm aimed at implementation on hardware devices. Comput Intell Neurosci:659050.

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