Home » Products » Stimulus Generators
Stimulus Generator
Completely Software Driven
two version for complex or simple pulses available
Current and Voltage Driven Stimulation
With the MC_Stimulus software you can choose between current or voltage driven stimulation.
Decide in favour of 2, 4 or even 8 completely independent stimulus outputs
Arbitrary Analog Waveforms
freely combine mono- or biphasic rectangular pulses, ramps, or sine waveforms to design a stimulation pattern of unlimited complexity.
You can do this on each output channel.
Integrated Isolation Units
Each of the 2, 4 or 8 output channels is optically isolated, efficiently avoiding cross-talk among channels.
No additional units, batteries and cables, no additional costs!
Each Channel - All Features - Full Flexibility
Each of the 2, 4 or 8 channels is completely independent.
For all kinds of stimulation patterns- there's no need to combine channels. Every single channel can be used for a complex stimulus output.
Three functions- One device
The Stimulus Generators from MCS are featuring:
- Current driven stimulation:
In current mode, the stimulus generator guarantees a stable current output in the range of -1.6 mA to +1.6 mA independent of the electrode impedance @ 120V compliance voltage.
On request, a version with an extended output range of ± 16 mA is available. - Voltage driven stimulation:
In voltage mode, the voltage level in the range of -8 V to +8 V is held constant and the current output depends on the electrode impedance. The lower the electrode impedance - the higher the output current.
The maximum output current is ± 20 mA. - Controlling and Timing
For every single stimulus output there is one TTL in- and output. The Stimulators can receive and deliver TTL pulses via BNC connectors.
These triggers allow you to control and synchronize other instruments like imaging systems, LED-lights, data acquisition systems and many more - at a 20μs precision.
For a broad range of applications
- Neuronal networks:
-Long time stimulation
-Feedback stimulation
-White noise stimulation
-Biological signals as stimulation patterns
-Multiple files can be applied to one or more electrodes - Brainslices:
-Flexible LTP induction patterns
-Studies of synaptic plasticity - Sceletal Muscle:
-Evoke isometric and isotonic contractions - Cardiac cells and tissues:
-Study influence of artificial pacemakers
-Pace cardiac cell cultures
-Pace tissue preparations like slices, purkinje fibers,
or papillary muscle
-Mimic cardiac environment during stem cell differentiation
Photoconductive Stimulation Device
"Non-invasive Controlled Depolarization of Excitable Cells"
The Photoconductive Stimulation Device enables neuroscience researchers and pharmaceutical technicians to depolarize dissociated neurons noninvasively and in a highly targeted manner.
- Non-invasive electrical stimulation can be done without causing damage to the cells
- Enables optical targeting of specific neurons to be depolarized
- Allows for the controlled variation of frequency and duration of stimulation
- Short or long term non-invasive cell specific stimulation
- A replacement for pharmacological agonist stimulation (KCL), which do not allow for targeting and repetitive depolarization
- The depolarization of a user-defined area of a dissociated culture, not just those cells positioned on an electrode
- A means for increasing the flexibility of protocol design by having more control over which cells are depolarized and when
- For controlled cell stimulation in combination with voltage sensitive dyes
- Depolarize cells with specific patterns of excitation, which allows for detailed investigation of excitable cells over time
- Significantly reduces the time and skill level required to obtain excitation, in that electrophysiology techniques and equipment are not required


