CMOS-Chip with 4225 recording sites
The chip is based on complementary metal oxide semiconductor (CMOS) technology, facilitating fast, high-resolution imaging of electrical activity.
The chip is equipped with a culture chamber to house your sample, while allowing the use of a microscope.
The recording sites are arranged in a 65x65 grid and have a 16µm or 32µm interelectrode distance (center to center). Between the recording electrodes, there is a grid of 32x32 bigger stimulation sites. Summarizing, you can record from 4225 electrodes and stimulate your sample at 1024 sites.
The high number of electrodes also results in a large recording area (1 mm² @ 16 µm; 4 mm² @ 32 µm). Thereby, you can see the signals from every single cell and even the signal propagation along an axon, while still getting an overview on your complete sample, e.g. a cell culture and see how the cells interact.
The chip is coated with planar oxide, similar to glass, enhancing the biocompatibility and biostability.