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The Portable-ME-System is a complete plug-and-play data acquisition system based on signal processing technology.
The Portable-ME-System is a all-in-one solution for tethered in-vivo/ex-vivo recordings. It is the perfect solution for recordings from anesthetized animals or Langendorff heart preparations.
The signal is picked up by an electrode array, which is connected to a miniature preamplifier. Here, the signal is amplified for the first time. Then, the pre-amplfied data goes into the core element of the set-up: The Portable-ME-System. It includes filter amplifier and data acquisition in one device and is available with 16 and 32 channels. From there, one USB-cable makes the connection to the computer, where the included data acquisition software MC_Rack analyses the data.
The Portable-ME-System can be operated with most commercially available probes.
Multi Channel Systems offers flexible MEAs, made of polyimide foil. They are available with 24, 36 and 72 electrodes and can easily be connected to MCS preamplifiers.
You can also use other electrode arrays. We recommend the use of probes from Neuronexus Technologies or ATLAS Neuroengineering.
Probes with Omnetics connector can ca connected directly to the micro preamplifiers µPA16 and µPA32. For other probe connectors, you might need an adapter. We have a wide range of adapters available. If you do not find the one you need, please contact us. We will certainly find a solution that fits your needs.
The miniature preamplifiers receive the signal from the electrode array and provide the first amplification step (tenfold amplification).
Multi Channel Systems offers miniature preamplifiers (MPA/µPA) with 2, 8, 16, and 32 channels, .
All miniature preamplifiers have additional common ground and reference electrode inputs. The metal cases provide electrical shielding. Stable long-term recordings are ensured by the high input impedance.
The main device Portable-ME-System fulfills two functions in one device:1. Signal amplification
2. Data acquisition from 16 or 32 channels
It is available in the following versions:
The real-time signal detection/feedback is an advantageous feature if you need fast and predictable reactions related to recorded analog signals without time delay. Before, the signal had to be analyzed by the computer, which led to an unpredictable time delay of the stimulus of at least 100 ms. By moving the analysis from the PC to the DSP (Digital Signal Processor) integrated in the Portable-ME-System, the detour is obsolete and the time delay is now far below 1 ms. All you need to do is to define the condition for the feedback and download it to the portable-ME-System (1). During recording (2), the DSP filters the data and detects spikes (3), checking whether your condition is fulfilled. When a designated event is detected, the connected stimulus generator generates the stimulus pulse (4).
The Portable-ME-Systems are compatible with all kinds of in vivo electrode arrays on the market. Spike activity from acute or chronically implanted electrodes can be recorded with high resolution. It is possible to monitor any channel as an audio output in real-time, which helps positioning the electrode in the brain. All relevant parameters can be monitored online on all channels. The screenshot on the right shows data from an electrode array chronically implanted in a rat brain. Spikes are sorted online, overall spike rate and unit-specific ISI are monitored simultaneously.
Flexible microelectrode arrays based on polyimide foil can be used to record from a large area at the surface of brain or heart in vivo or ex vivo. The flexibility of the array allows an optimal electrode-to- tissue contact on uneven surfaces. The image on the left shows signals recorded from a rat barrel cortex with a 32-channel FlexMEA. Signals are averaged and high pass filtered and the minimum of the first signal component is monitored online.
Cardio2D is a software package to record cardiac data and analyze for spatial properties of cardiac signal propagation. With the Portable-ME-System it is possible to perform epicardial mapping recordings or map signal propagation in cardiac slices. Cardio2D obtains false color coded maps with isochronous lines for local activation times. Conduction velocity is calculated automatically.
You can purchase the Cardio2D software package separately.
Multi Channel Systems has a team of highly-qualified scientists, whose only task is to help you with any issue you might have. No matter whether you want to know whether your biological sample is suitable for MEA recordings or if you have a specific software question: Our support team is here to help you.
We have scientists who earned their PhDs in the fields of biology, biophysics, and biochemistry and specialized in:
Our sales team has years of experience in electrophysiology, too. They can help you in choosing the right system for your specific application, give you advice on the general set-up and useful accessories. They are happy to visit you in your lab anytime to:
Worldwide, we are supported by our distribution partners. We have long-lasting cooperations with all of our partners and they are regularly trained on our equipment. Be sure that they have the expertise to advise you on all MCS-Systems.
Please do not hesitate to contact us. Normally, we reply to you within 24 hours. You can contact us via:
Portable-ME-System with 16-channel filter amplifier and data acquisition. With either 2 MPA8I or 1 µPA16 headstage pre-amplifier.
Portable-ME-System with 32-channel filter amplifier and data acquisition. With either 2 µPA16 or 1 µPA32 headstage pre-amplifier.
Portable-ME-System with 16-channel filter amplifier and data acquisition. With 2 MPA8I headstage pre-amplifiers.
Portable-ME-System with 32-channel filter amplifier and data acquisition. With either 4 MPA8I or 1 MPA32I headstage pre-amplifier.