Innovations in Electrophysiology

Technological developments

Arbogast T, Iacono G, Chevalier C, Afinowi NO, Houbaert X, van Eede MC, Laliberte C, Birling MC, Linda K, Meziane H, Selloum M, Sorg T, Nadif Kasri N, Koolen DA, Stunnenberg HG, Henkelman RM, Kopanitsa M, Humeau Y, De Vries BBA, Herault Y (2017) Mouse models of 17q21.31 microdeletion and microduplication syndromes highlight the importance of Kansl1 for cognition. PLoS Genet 13:e1006886.

Artyukhov AS, Dashinimaev EB, Tsvetkov VO, Bolshakov AP, Konovalova EV, Kolbaev SN, Vorotelyak EA, Vasiliev AV (2017) New genes for accurate normalization of qRT-PCR results in study of iPS and iPS-derived cells. Gene 626:234-240.

Blaschke BM, Tort-Colet N, Guimerà-Brunet A, Weinert J, Rousseau L, Heimann A, Drieschner S, Kempski O, Villa R, Sanchez-Vives MV, Garrido JA (2017) Mapping brain activity with flexible graphene micro-transistors. 2D Materials 4:025040.

Bottrich M, Tanskanen JMA, Hyttinen JAK (2017) Lead field theory provides a powerful tool for designing microelectrode array impedance measurements for biological cell detection and observation. Biomed Eng Online 16:85.

Bridges DC, Tovar KR, Wu B, Hansma PK, Kosik KS (2017) MEA Viewer: a High-performance Interactive Application for Visualizing Electrophysiological Data. bioRxiv.

Can UI, Nagarajan N, Vural DC, Zorlutuna P (2017) Muscle-Cell-Based “Living Diodes”. Advanced Biosystems 1:n/a-n/a.

Cools J, Copic D, Luo Z, Callewaert G, Braeken D, De Volder M (2017) 3D Microstructured Carbon Nanotube Electrodes for Trapping and Recording Electrogenic Cells. Advanced Functional Materials:n/a-n/a.

Dermutz H, Thompson-Steckel G, Forro C, de Lange V, Dorwling-Carter L, Voros J, Demko L (2017) Paper-based patterned 3D neural cultures as a tool to study network activity on multielectrode arrays. RSC Advances 7:39359-39371.

Ellis BW, Acun A, Can UI, Zorlutuna P (2017) Human iPSC-derived myocardium-on-chip with capillary-like flow for personalized medicine. Biomicrofluidics 11:024105.

Frega M, van Gestel SHC, Linda K, van der Raadt J, Keller J, Van Rhijn J-R, Schubert D, Albers CA, Nadif Kasri N (2017) Rapid Neuronal Differentiation of Induced Pluripotent Stem Cells for Measuring Network Activity on Micro-electrode Arrays. JoVE:e54900.

Giacomelli E, Bellin M, Sala L, van Meer BJ, Tertoolen LGJ, Orlova VV, Mummery CL (2017) Three-dimensional cardiac microtissues composed of cardiomyocytes and endothelial cells co-differentiated from human pluripotent stem cells. Development 144:1008-1017.

Habibey R, Latifi S, Mousavi H, Pesce M, Arab-Tehrany E, Blau A (2017) A multielectrode array microchannel platform reveals both transient and slow changes in axonal conduction velocity. Sci Rep 7:8558.

Hulsmann J, Aubin H, Wehrmann A, Lichtenberg A, Akhyari P (2017) The impact of left ventricular stretching in model cultivations with neonatal cardiomyocytes in a whole-heart bioreactor. Biotechnol Bioeng 114:1107-1117.

Jung H, Kang H, Nam Y (2017) Digital micromirror based near-infrared illumination system for plasmonic photothermal neuromodulation. Biomedical Optics Express 8:2866-2878.

Ko H, Lee S (2017) Electrical characterization of 2D and 3D microelectrodes for achieving high-resolution sensing in retinal prostheses with in vitro animal experimental results. Microsystem Technologies 23:473-481.

Kreutzer J, Yla-Outinen L, Maki AJ, Ristola M, Narkilahti S, Kallio P (2017) Cell culture chamber with gas supply for prolonged recording of human neuronal cells on microelectrode array. J Neurosci Methods 280:27-35.

Laprell L, Tochitsky I, Kaur K, Manookin MB, Stein M, Barber DM, Schon C, Michalakis S, Biel M, Kramer RH, Sumser MP, Trauner D, Van Gelder RN (2017) Photopharmacological control of bipolar cells restores visual function in blind mice. J Clin Invest 127:2598-2611.

Lecomte A, A. D, Descamps E, Dahan L, Bergaud C (2017) In vitro and in vivo biostability assessment of chronically-implanted Parylene C neural sensors. Sensors and Actuators B: Chemical.

Maoz BM, Herland A, Henry OYF, Leineweber WD, Yadid M, Doyle J, Mannix R, Kujala VJ, FitzGerald EA, Parker KK, Ingber DE (2017) Organs-on-Chips with combined multi-electrode array and transepithelial electrical resistance measurement capabilities. Lab Chip 17:2294-2302.

Narula U, Ruiz A, McQuaide M, DeMarse TB, Wheeler BC, Brewer GJ (2017) Narrow microtunnel technology for the isolation and precise identification of axonal communication among distinct hippocampal subregion networks. PLoS ONE 12:e0176868.

Sadleir RJ, Fu F, Falgas C, Holland S, Boggess M, Grant SC, Woo EJ (2017) Direct detection of neural activity in vitro using magnetic resonance electrical impedance tomography (MREIT). Neuroimage 161:104-119.

Simon DM, Charkhkar H, St John C, Rajendran S, Kang T, Reit R, Arreaga-Salas D, McHail DG, Knaack GL, Sloan A, Grasse D, Dumas TC, Rennaker RL, Pancrazio JJ, Voit WE (2017) Design and demonstration of an intracortical probe technology with tunable modulus. J Biomed Mater Res A 105:159-168.

Tochitsky I, Trautman J, Gallerani N, Malis JG, Kramer RH (2017) Restoring visual function to the blind retina with a potent, safe and long-lasting photoswitch. Sci Rep 7:45487.

Vuorenpaa H, Penttinen K, Heinonen T, Pekkanen-Mattila M, Sarkanen JR, Ylikomi T, Aalto-Setala K (2017) Maturation of human pluripotent stem cell derived cardiomyocytes is improved in cardiovascular construct. Cytotechnology.

Zeck G, Jetter F, Channappa L, Bertotti G, Thewes R (2017) Electrical Imaging: Investigating Cellular Function at High Resolution. Advanced Biosystems:1700107-n/a.

Zhang L, Li X, Yu X, Li Y, Sun A, Huang C, Xu F, Guo J, Sun Y, Zhang X, Yang X, Zhang C (2017) Construction of vascularized pacemaker tissues by seeding cardiac progenitor cells and endothelial progenitor cells into Matrigel. Life Sci 179:139-146.

Berglund K, Tung JK, Higashikubo B, Gross RE, Moore CI, Hochgeschwender U (2016) Combined Optogenetic and Chemogenetic Control of Neurons. Methods Mol Biol 1408:207-225.

Buehler S, Stubbe M, Bonk S, Nissen M, Titipornpun K, Klinkenberg E-D, Baumann W, Gimsa J (2016) Cell Monitoring and Manipulation Systems (CMMSs) based on Glass Cell-Culture Chips (GC3s). Micromachines 7:106.

Dvorkin R, Ziv NE (2016) Relative Contributions of Specific Activity Histories and Spontaneous Processes to Size Remodeling of Glutamatergic Synapses. PLoS Biol 14:e1002572.

Eleftheriou CG, Zimmermann JB, Kjeldsen HD, David-Pur M, Hanein Y, Sernagor E (2016) Carbon nanotube electrodes for retinal implants: a study of structural and functional integration over time. bioRxiv.

Fan X, Song Y, Ma Y, Zhang S, Xiao G, Yang L, Xu H, Zhang D, Cai X (2016) In Situ Real-Time Monitoring of Glutamate and Electrophysiology from Cortex to Hippocampus in Mice Based on a Microelectrode Array. Sensors (Basel) 17.

Frega M (2016) Neuronal Network Dynamics in 2D and 3D in vitro Neuroengineered Systems. PhD.

Hasan F, Berdichevsky Y (2016) Neural Circuits on a Chip. Micromachines 7.

Iftikhar H (2016) Transparent Indium Tin Oxide Microelectrode Arrays for Measuring Beating Cardiomyocytes.

Killian NJ, Vernekar VN, Potter SM, Vukasinovic J (2016) A Device for Long-Term Perfusion, Imaging, and Electrical Interfacing of Brain Tissue In vitro. Front Neurosci 10:135.

Klatt N, Scherschel K, Schad C, Lau D, Reitmeier A, Kuklik P, Muellerleile K, Yamamura J, Zeller T, Steven D, Baldus S, Schaffer B, Jungen C, Eickholt C, Wassilew K, Schwedhelm E, Willems S, Meyer C (2016) Development of nonfibrotic left ventricular hypertrophy in an ANG II-induced chronic ovine hypertension model. Physiol Rep 4.

Knudsen AM (2016) NTNU Cyborg: A study into embodying Neuronal Cultures through Robotic Systems. Department of Engineering Cybernetics.

Lee S, Yen SC, Sheshadri S, Delgado-Martinez I, Xue N, Xiang Z, Thakor NV, Lee C (2016) Flexible Epineural Strip Electrode for Recording in Fine Nerves. IEEE Trans Biomed Eng 63:581-587.

Li Y, Sun R, Wang Y, Li H, Zheng X (2016) A Novel Robot System Integrating Biological and Mechanical Intelligence Based on Dissociated Neural Network-Controlled Closed-Loop Environment. PLoS ONE 11:e0165600.

Massobrio P, Massobrio G, Martinoia S (2016) Interfacing Cultured Neurons to Microtransducers Arrays: A Review of the Neuro-Electronic Junction Models. Front Neurosci 10:282.

Naughton JR, Connolly T, Varela JA, Lundberg J, Burns MJ, Chiles TC, Christianson JP, Naughton MJ (2016) Shielded Coaxial Optrode Arrays for Neurophysiology. Front Neurosci 10:252.

Oyunbaatar NE, Lee DH, Patil SJ, Kim ES, Lee DW (2016) Biomechanical Characterization of Cardiomyocyte Using PDMS Pillar with Microgrooves. Sensors (Basel) 16.

Pastore VP, Poli D, Godjoski A, Martinoia S, Massobrio P (2016) ToolConnect: A Functional Connectivity Toolbox for In vitro Networks. Front Neuroinform 10:13.

Pigareva Y, Malishev E, Gladkov A, Kolpakov V, Bukatin A, Mukhina I, Kazantsev V, Pimashkin A (2016) Neural signal registration and analysis of axons grown in microchannels. Journal of Physics: Conference Series 741.

Pinnell RC, Almajidy RK, Kirch RD, Cassel JC, Hofmann UG (2016) A Wireless EEG Recording Method for Rat Use inside the Water Maze. PLoS ONE 11:e0147730.

Pisano F (2016) Advanced technologies for spatio-temporal control of neural circuits using optogenetics. Department of Physics.

Rabieh N, Ojovan SM, Shmoel N, Erez H, Maydan E, Spira ME (2016) On-chip, multisite extracellular and intracellular recordings from primary cultured skeletal myotubes. Sci Rep 6:36498.

Reinhard K, Mutter M, Gustafsson E, Gustafsson L, Vaegler M, Schultheiss M, Muller S, Yoeruek E, Schrader M, Munch TA (2016) Hypothermia Promotes Survival of Ischemic Retinal Ganglion Cells. Invest Ophthalmol Vis Sci 57:658-663.

Ryu JR, Jang MJ, Jo Y, Joo S, Lee do H, Lee BY, Nam Y, Sun W (2016) Synaptic compartmentalization by micropatterned masking of a surface adhesive cue in cultured neurons. Biomaterials 92:46-56.

Shmoel N, Rabieh N, Ojovan SM, Erez H, Maydan E, Spira ME (2016) Multisite electrophysiological recordings by self-assembled loose-patch-like junctions between cultured hippocampal neurons and mushroom-shaped microelectrodes. Sci Rep 6:27110.

Vardi R, Goldental A, Sardi S, Sheinin A, Kanter I (2016) Simultaneous multi-patch-clamp and extracellular-array recordings: Single neuron reflects network activity. Sci Rep 6:36228.

Wanke E, Gullo F, Dossi E, Valenza G, Becchetti A (2016) Neuron-glia crosstalk revealed in reverberating networks by simultaneous extracellular recording of spikes and astrocytes' glutamate transporter and K+ currents. J Neurophysiol:jn 00509 02016.

Welkenhuysen M, Hoffman L, Luo Z, De Proft A, Van den Haute C, Baekelandt V, Debyser Z, Gielen G, Puers R, Braeken D (2016) An integrated multi-electrode-optrode array for in vitro optogenetics. Sci Rep 6:20353.

Wijdenes P, Ali H, Armstrong R, Zaidi W, Dalton C, Syed NI (2016) A novel bio-mimicking, planar nano-edge microelectrode enables enhanced long-term neural recording. Sci Rep 6:34553.

Wilk N, Habibey R, Golabchi A, Latifi S, Ingebrandt S, Blau A (2016) Selective comparison of gelling agents as neural cell culture matrices for long-term microelectrode array electrophysiology. OCL 23.

Zhang Q, Zhang D, Li N, Lu Y, Yao Y, Li S, Liu Q (2016) Zinc Nanoparticles-equipped Bioelectronic Nose Using a Microelectrode Array for Odorant Detection. Analytical Sciences 32.

Bartsch H, Himmerlich M, Fischer M, Demkó L, Hyttinen J, Schober A (2015) LTCC-Based Multi-Electrode Arrays for 3D in Vitro Cell Cultures. Journal of Ceramic Science and Technology 6:315-324.

Biffi E (2015) Microfluidic and Compartmentalized Platforms for Neurobiological Research. Heidelberg: Springer.

Biro I, Giugliano M (2015) A reconfigurable visual-programming library for real-time closed-loop cellular electrophysiology. Front Neuroinform 9:17.

Charkhkar H (2015) Microelectrode Arrays for Neuronal Recordings: Developing Novel Technology and Applications. Doctor of Philosophy.

Dipalo M, Messina GC, Amin H, La Rocca R, Shalabaeva V, Simi A, Maccione A, Zilio P, Berdondini L, De Angelis F (2015) 3D plasmonic nanoantennas integrated with MEA biosensors. Nanoscale 7:3703-3711.

Dranias MR, Westover MB, Cash S, VanDongen AM (2015) Stimulus information stored in lasting active and hidden network states is destroyed by network bursts. Front Integr Neurosci 9:14.

Farah N, Levinsky A, Brosh I, kahn I, Shoam S (2015) Holographic fiber bundle system for patterned optogenetic activation of large-scale neuronal networks. Neurophotonics 2.

Georgiadis V, Stephanou A, Townsend PA, Jackson TR (2015) MultiElec: A MATLAB Based Application for MEA Data Analysis. PLoS ONE 10:e0129389.

Goldental A, Sabo P, Sardi S, Vardi R, Kanter I (2015) Mimicking Collective Firing Patterns of Hundreds of Connected Neurons using a Single-Neuron Experiment. Front Neurosci 9:508.

Grundmann D, Klotz M, Rabe H, Glanemann M, Schafer KH (2015) Isolation of high-purity myenteric plexus from adult human and mouse gastrointestinal tract. Sci Rep 5:9226.

Habibey R, Golabchi A, Latifi S, Difato F, Blau A (2015) A microchannel device tailored to laser axotomy and long-term microelectrode array electrophysiology of functional regeneration. Lab Chip 15:4578-4590.

Kanner S, Bisio M, Cohen G, Goldin M, Tedesco M, Hanein Y, Ben-Jacob E, Barzilai A, Chiappalone M, Bonifazi P (2015) Design, Surface Treatment, Cellular Plating, and Culturing of Modular Neuronal Networks Composed of Functionally Inter-connected Circuits.e52572.

Kim R, Nam Y (2015) Electrochemical layer-by-layer approach to fabricate mechanically stable platinum black microelectrodes using a mussel-inspired polydopamine adhesive. J Neural Eng 12:026010.

Mondal A, Baker B, Harvey IR, Moreno AP (2015) PerFlexMEA: a thin microporous microelectrode array for in vitro cardiac electrophysiological studies on hetero-cellular bilayers with controlled gap junction communication. Lab Chip 15:2037-2048.

Nagarah JM, Stowasser A, Parker RL, Asari H, Wagenaar DA (2015) Optically transparent multi-suction electrode arrays. Front Neurosci 9:384.

Newman JP, Fong MF, Millard DC, Whitmire CJ, Stanley GB, Potter SM (2015) Optogenetic feedback control of neural activity. Elife 4:e07192.

Nick C, Schlaak HF, Thielemann C (2015) Simulation and Measurement of Neuroelectrodes´ Characteristics with Integrated High Aspect Ratio Nano Structures. Materials Science 2:189-202.

Nussinovitch U, Gepstein L (2015) Optogenetics for suppression of cardiac electrical activity in human and rat cardiomyocyte cultures. Neurophotonics 2:031204.

Pedraza E, Karajic A, Raoux M, Perrier R, Pirog A, Lebreton F, Arbault S, Gaitan J, Renaud S, Kuhn A, Lang J (2015) Guiding pancreatic beta cells to target electrodes in a whole-cell biosensor for diabetes. Lab Chip.

Piret G, Hebert C, Mazellier JP, Rousseau L, Scorsone E, Cottance M, Lissorgues G, Heuschkel MO, Picaud S, Bergonzo P, Yvert B (2015) 3D-nanostructured boron-doped diamond for microelectrode array neural interfacing. Biomaterials 53:173-183.

Pirino V, Riccomagno E, Martinoia S, Massobrio P (2015) A topological study of repetitive co-activation networks in in vitro cortical assemblies. Phys Biol 12:016007.

Rast G, Weber J, Disch C, Schuck E, Ittrich C, Guth BD (2015) An integrated platform for simultaneous multi-well field potential recording and Fura-2-based calcium transient ratiometry in human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes. J Pharmacol Toxicol Methods.

Regalia G, Biffi E, Ferrigno G, Pedrocchi A (2015) A low-noise, modular, and versatile analog front-end intended for processing in vitro neuronal signals detected by microelectrode arrays. Comput Intell Neurosci 2015:172396.

Ren Y, Huang S, Mosser S, Heuschkel M, Bertsch A, Fraering PC, Chen JJ, Renaud P (2015) A Simple and Reliable PDMS and SU-8 Irreversible Bonding Method and Its Application on a Microfluidic-MEA Device for Neuroscience Research. Micromachines 6:1923-1934.

Saalfrank D, Konduri AK, Latifi S, Habibey R, Golabchi A, Martiniuc AV, Knoll A, Ingebrandt S, Blau A (2015) Incubator-independent cell-culture perfusion platform for continuous long-term microelectrode array electrophysiology and time-lapse imaging. R Soc Open Sci 2:150031.

Samba R, Herrmann T, Zeck G (2015) PEDOT-CNT coated electrodes stimulate retinal neurons at low voltage amplitudes and low charge densities. J Neural Eng 12:016014.

Samhaber R, Schottdorf M, Hady AE, Broking K, Daus A, Thielemann C, Stuhmer W, Wolf F (2015) Growing neuronal islands on multi-electrode arrays using an Accurate Positioning-muCP device. J Neurosci Methods.

Schonecker S, Kraushaar U, Guenther E, Gerst F, Ullrich S, Haring HU, Konigsrainer A, Barthlen W, Drews G, Krippeit-Drews P (2015) Human Islets Exhibit Electrical Activity on Microelectrode Arrays (MEA). Exp Clin Endocrinol Diabetes.

Smith I, Haag M, Ugbode C, Tams D, Rattray M, Przyborski S, Bithell A, Whalley BJ (2015) Neuronal-glial populations form functional networks in a biocompatible 3D scaffold. Neurosci Lett 609:198-202.

Smith I, Silveirinha V, Stein JL, de la Torre-Ubieta L, Farrimond JA, Williamson EM, Whalley BJ (2015) Human neural stem cell-derived cultures in three-dimensional substrates form spontaneously functional neuronal networks. J Tissue Eng Regen Med.

Spanu A, Lai S, Cosseddu P, Tedesco M, Martinoia S, Bonfiglio A (2015) An organic transistor-based system for reference-less electrophysiological monitoring of excitable cells. Sci Rep 5:8807.

Tedesco M, Frega M, Martinoia S, Pesce M, Massobrio P (2015) Interfacing 3D Engineered Neuronal Cultures to Micro-Electrode Arrays: An Innovative In Vitro Experimental Model. J Vis Exp:e53080.

Tessadori J, Chiappalone M (2015) Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks.e52341.

Tolstosheeva E, Gordillo-Gonzalez V, Biefeld V, Kempen L, Mandon S, Kreiter AK, Lang W (2015) A multi-channel, flex-rigid ECoG microelectrode array for visual cortical interfacing. Sensors (Basel) 15:832-854.

Bertotti G, Velychko D, Dodel N, Keil S, Wolansky D, Tillak B, Schreiter M, Grall A, Jesinger P, Möller A, Boven KH, Röhler S, Eickenscheidt M, Stett A, Zeck G, Thewes R (2014) A CMOS-Based Sensor Array for In-Vitro Neural Tissue Interfacing with 4225 Recording Sites and 1024 Stimulation Sites. In: BioCAS. Lausanne.

Bingen BO, Engels MC, Schalij MJ, Jangsangthong W, Neshati Z, Feola I, Ypey DL, Askar SF, Panfilov AV, Pijnappels DA, de Vries AA (2014) Light-induced termination of spiral wave arrhythmias by optogenetic engineering of atrial cardiomyocytes. Cardiovasc Res 104:194-205.

Eglen SJ, Weeks M, Jessop M, Simonotto J, Jackson T, Sernagor E (2014) A data repository and analysis framework for spontaneous neural activity recordings in developing retina. Gigascience 3:3.

Fattahi P, Yang G, Kim G, Abidian MR (2014) A review of organic and inorganic biomaterials for neural interfaces. Adv Mater 26:1846-1885.

Frega M, Tedesco M, Massobrio P, Pesce M, Martinoia S (2014) Network dynamics of 3D engineered neuronal cultures: a new experimental model for in-vitro electrophysiology. Sci Rep 4:5489.

George JB, Abraham GM, Singh K, Ankolekar SM, Amrutur B, Sikdar SK (2014) Input coding for neuro-electronic hybrid systems. Biosystems 126C:1-11.

Keren H, Marom S (2014) Controlling neural network responsiveness: tradeoffs and constraints. Front Neuroeng 7:11.

Kim R, Joo S, Jung H, Hong N, Nam Y (2014) Recent trends in microelectrode array technology for in vitro neural interface platform. Biomedical Engineering Letters 4:129-141.

Lin ZC, Xie C, Osakada Y, Cui Y, Cui B (2014) Iridium oxide nanotube electrodes for sensitive and prolonged intracellular measurement of action potentials. Nat Commun 5:3206.

Mahmud M, Pulizzi R, Vasilaki E, Giugliano M (2014) QSpike tools: a generic framework for parallel batch preprocessing of extracellular neuronal signals recorded by substrate microelectrode arrays. Front Neuroinform 8:26.

Nick C, Thielemann C (2014) Are Carbon Nanotube Microelectrodes Manufactured from Dispersion Stable Enough for Neural Interfaces? BioNanoScience:1-10.

Pan ZH, Ganjawala TH, Lu Q, Ivanova E, Zhang Z (2014) ChR2 mutants at L132 and T159 with improved operational light sensitivity for vision restoration. PLoS ONE 9:e98924.

Quasthoff K, Ferrea S, Fleischer W, Theiss S, Schnitzler A, Dihne M, Walter J (2014) Freshly frozen E18 rat cortical cells can generate functional neural networks after standard cryopreservation and thawing procedures. Cytotechnology.

Reinhard K, Tikidji-Hamburyan A, Seitter H, Idrees S, Mutter M, Benkner B, Munch TA (2014) Step-By-Step Instructions for Retina Recordings with Perforated Multi Electrode Arrays. PLoS ONE 9:e106148.

Schonecker S, Kraushaar U, Dufer M, Sahr A, Hardtner C, Guenther E, Walther R, Lendeckel U, Barthlen W, Krippeit-Drews P, Drews G (2014) Long-term culture and functionality of pancreatic islets monitored using microelectrode arrays. Integr Biol (Camb).

Stutzki H, Leibig C, Andreadaki A, Fischer D, Zeck G (2014) Inflammatory stimulation preserves physiological properties of retinal ganglion cells after optic nerve injury. Front Cell Neurosci 8:38.

Xu B, Binczak S, Jacquir S, Pont O, Yahia H (2014) Complexity analysis of experimental cardiac arrhythmia. In: 2014 IEEE Region 10 Technical Symposium (TENSYMP). Kuala Lumpur.

Blau A (2013) Cell adhesion promotion strategies for signal transduction enhancement in

microelectrode array in vitro electrophysiology: An introductory overview and

critical discussion. Current Opinion in Colloid & Interface Science 18:481-492.

Brewer GJ, Boehler MD, Leondopulos S, Pan L, Alagapan S, Demarse TB, Wheeler BC (2013) Toward a self-wired active reconstruction of the hippocampal trisynaptic loop: DG-CA3. Front Neural Circuits 7:165.

David-Pur M, Bareket-Keren L, Beit-Yaakov G, Raz-Prag D, Hanein Y (2013) All-carbon-nanotube flexible multi-electrode array for neuronal recording and stimulation. Biomed Microdevices.

Gabriel G, Illa X, Guimera A, Rebollo B, Hernández-Ferrer J, Martin-Fernandez I, Martínez MT, Godignon P, Sanchez-Vives MV, Villa R (2013) Carbon Nanotubes as Suitable Interface for Improving Neural Recordings. In.

Huang S, Uusisaari MY (2013) Physiological temperature during brain slicing enhances the quality of acute slice preparations. Front Cell Neurosci 7:48.

Jahnke HG, Heimann A, Azendorf R, Mpoukouvalas K, Kempski O, Robitzki AA, Charalampaki P (2013) Impedance spectroscopy--an outstanding method for label-free and real-time discrimination between brain and tumor tissue in vivo. Biosens Bioelectron 46:8-14.

Kim YH, Kim GH, Baek NS, Han YH, Kim AY, Chung MA, Jung SD (2013) Fabrication of multi-electrode array platforms for neuronal interfacing with bi-layer lift-off resist sputter deposition. JOURNAL OF MICROMECHANICS AND MICROENGINEERING 23.

Langhammer CG, Kutzing MK, Luo V, Zahn JD, Firestein BL (2013) A topographically modified substrate-embedded MEA for directed myotube formation at electrode contact sites. Ann Biomed Eng 41:408-420.

Martinelli V, Cellot G, Fabbro A, Bosi S, Mestroni L, Ballerini L (2013) Improving cardiac myocytes performance by carbon nanotubes platforms. Front Physiol 4:239.

Menz MD, Oralkan O, Khuri-Yakub PT, Baccus SA (2013) Precise neural stimulation in the retina using focused ultrasound. J Neurosci 33:4550-4560.

Moretti D, Garenne A, Haro E, Poulletierde Gannes F, Lagroye I, Leveque P, Veyret B, Lewis N (2013) InVitro Exposureof Neuronal Networkstoa GSM-1800 Signal. Bioelectromagnetics.

Narkilahti S (2013) SpikeBooster culture chambers for MEA. In.

Ness TB, Hagen E, Negwer M, Bakker R, Schubert D, Einevoll GT (2013) Modeling Extracellular Potentials in Microelectrode Array Recordings. In.

Nguyen QV, Caro A, Raoux M, Quotb A, Floderer JB, Bornat Y, Renaud S, Lang J (2013) A novel bioelectronic glucose sensor to process distinct electrical activities of pancreatic beta-cells. Conf Proc IEEE Eng Med Biol Soc 2013:172-175.

Nick C, Goldhammer M, Bestel R, Steger F, Daus AW, Thielemann C (2013) DrCell – A Software Tool for the Analysis of Cell Signals Recorded with Extracellular Microelectrodes Signal Processing: An International Journal (SPIJ) 7.

Pradhapan P, Kuusela J, Viik J, Aalto-Setala K, Hyttinen J (2013) Cardiomyocyte MEA data analysis (CardioMDA)--a novel field potential data analysis software for pluripotent stem cell derived cardiomyocytes. PLoS ONE 8:e73637.

Schmidt J, Foulser A, Frohlich F (2013) Brain Stimulation by Network Resonance with Weak Electric Fields Probed by Optogenetics in Vitro. In.

Schönecker S, Kraushaar U, Guenther E, Düfer M, Sahr A, Härdtner C, Walther R, Lendeckel U, Barthlen W, Krippeit-Drews P, Drews G (2013) Microelectrode arrays as a new approach in beta-cell research: from mice to men In: EASD-Meeting. Barcelona.

Sivasubramaniapandian M (2013) The effect of coatings on the performance of microelectrode arrays. Faculty of Natural Sciences Master of Science 80.

Spira ME, Hai A (2013) Multi-electrode array technologies for neuroscience and cardiology. Nat Nanotechnol 8:83-94.

Vardi R, Guberman S, Goldental A, Kanter I (2013) An experimental evidence-based computational paradigm for new logic-gates in neuronal activity. EPL (Europhysics Letters) 103.

Bareket-Keren L, Hanein Y (2012) Carbon nanotube-based multi electrode arrays for neuronal interfacing: progress and prospects. Front Neural Circuits 6:122.

Becchetti A, Gullo F, Bruno G, Dossi E, Lecchi M, Wanke E (2012) Exact distinction of excitatory and inhibitory neurons in neural networks: a study with GFP-GAD67 neurons optically and electrophysiologically recognized on multielectrode arrays. Front Neural Circuits 6:63.

Bestel R, Daus AW, Thielemann C (2012) A novel automated spike sorting algorithm with adaptable feature extraction. J Neurosci Methods 211:168-178.

Biffi E, Piraino F, Pedrocchi A, Fiore GB, Ferrigno G, Redaelli A, Menegon A, Rasponi M (2012) A microfluidic platform for controlled biochemical stimulation of twin neuronal networks. Biomicrofluidics 6:24106-2410610.

Daus AW, Layer PG, Thielemann C (2012) A spheroid-based biosensor for the label-free detection of drug-induced field potential alterations. Sensors and Actuators B: Chemical 165:53-58.

Eickenscheidt M, Jenkner M, Thewes R, Fromherz P, Zeck G (2012) Electrical stimulation of retinal neurons in epiretinal and subretinal configuration using a multicapacitor array. J Neurophysiol 107:2742-2755.

Fendyur A, Spira ME (2012) Toward on-chip, in-cell recordings from cultured cardiomyocytes by arrays of gold mushroom-shaped microelectrodes. Front Neuroeng 5:21.

Gerwig R, Fuchsberger K, Schroeppel B, Link GS, Heusel G, Kraushaar U, Schuhmann W, Stett A, Stelzle M (2012) PEDOT-CNT Composite Microelectrodes for Recording and Electrostimulation Applications: Fabrication, Morphology, and Electrical Properties. Front Neuroeng 5:8.

Heim M, Rousseau L, Reculusa S, Urbanova V, Mazzocco C, Joucla S, Bouffier L, Vytras K, Bartlett P, Kuhn A, Yvert B (2012) Combined macro-/mesoporous microelectrode arrays for low-noise extracellular recording of neural networks. J Neurophysiol 108:1793-1803.

Jahnke HG, Braesigk A, Mack TG, Ponick S, Striggow F, Robitzki AA (2012) Impedance spectroscopy based measurement system for quantitative and label-free real-time monitoring of tauopathy in hippocampal slice cultures. Biosens Bioelectron 32:250-258.

Kanagasabapathi TT, Massobrio P, Barone RA, Tedesco M, Martinoia S, Wadman WJ, Decre MM (2012) Functional connectivity and dynamics of cortical-thalamic networks co-cultured in a dual compartment device. J Neural Eng 9:036010.

Kiran R (2012) Electrodes en diamant pour la fabrication de microsystèmes électrochimiques pour applications biologiques.

Kiran R, Rousseau L, Lissorgues G, Scorsone E, Bongrain A, Yvert B, Picaud S, Mailley P, Bergonzo P (2012) Multichannel boron doped nanocrystalline diamond ultramicroelectrode arrays: design, fabrication and characterization. Sensors (Basel) 12:7669-7681.

Levy O, Ziv NE, Marom S (2012) Enhancement of neural representation capacity by modular architecture in networks of cortical neurons. Eur J Neurosci 35:1753-1760.

Liu Q, Hu N, Zhang F, Zhang D, Hsia KJ, Wang P (2012) Olfactory epithelium biosensor: odor discrimination of receptor neurons from a bio-hybrid sensing system. Biomed Microdevices.

Ma Z, Liu Q, Liu H, Yang H, Yun JX, Eisenberg C, Borg TK, Xu M, Gao BZ (2012) Laser-patterned stem-cell bridges in a cardiac muscle model for on-chip electrical conductivity analyses. Lab Chip 12:566-573.

Marconi E, Nieus T, Maccione A, Valente P, Simi A, Messa M, Dante S, Baldelli P, Berdondini L, Benfenati F (2012) Emergent functional properties of neuronal networks with controlled topology. PLoS ONE 7:e34648.

Meyer T, Guenther E, Kraushaar U (2012) Microelectrode Arrays in Cardiac Mapping. In: Cardiac Mapping (Shenasa M, Hindricks G, Borggrefe M, Breithardt G, Josephson ME, eds).

Mourot A, Fehrentz T, Le Feuvre Y, Smith CM, Herold C, Dalkara D, Nagy F, Trauner D, Kramer RH (2012) Rapid optical control of nociception with an ion-channel photoswitch. Nat Methods 9:396-402.

Newman JP, Zeller-Townson R, Fong MF, Arcot Desai S, Gross RE, Potter SM (2012) Closed-Loop, Multichannel Experimentation Using the Open-Source NeuroRighter Electrophysiology Platform. Front Neural Circuits 6:98.

Nick C, Joshi R, Schneider JJ, Thielemann C (2012) Three-dimensional carbon nanotube electrodes for extracellular recording of cardiac myocytes. Biointerphases 7:58.

Quotb A, Bornat Y, Raoux M, Lang J, Renaud S (2012) NeuroBetaMed: A re-configurable wavelet-based event detection circuit for in vitro biological signals. In: Circuits and Systems (ISCAS), 2012 IEEE International Symposium.

Tessadori J, Bisio M, Martinoia S, Chiappalone M (2012) Modular neuronal assemblies embodied in a closed-loop environment: toward future integration of brains and machines. Front Neural Circuits 6:99.

Xie C, Lin Z, Hanson L, Cui Y, Cui B (2012) Intracellular recording of action potentials by nanopillar electroporation. Nat Nanotechnol 7:185-190.

Abdoun O, Joucla S, Mazzocco C, Yvert B (2011) NeuroMap: A Spline-Based Interactive Open-Source Software for Spatiotemporal Mapping of 2D and 3D MEA Data. Front Neuroinformatics 4:119.

Abilez OJ, Wong J, Prakash R, Deisseroth K, Zarins CK, Kuhl E (2011) Multiscale computational models for optogenetic control of cardiac function. Biophys J 101:1326-1334.

Al-Gayem Q, Richardson A, Liu H, Burd N (2011) An Oscillation-Based Technique for Degradation Monitoring of Sensing and Actuation Electrodes Within Microfluidic Systems. Journal of Electronic Testing:1-13.

Blau A (2011) Prospects for Neuroprosthetics: Flexible Microelectrode Arrays with Polymer Conductors. In: Applied Biomedical Engineering.

Difato F, Dal Maschio M, Marconi E, Ronzitti G, Maccione A, Fellin T, Berdondini L, Chieregatti E, Benfenati F, Blau A (2011) Combined optical tweezers and laser dissector for controlled ablation of functional connections in neural networks. J Biomed Opt 16:051306.

Fendyur A, Mazurski N, Shappir J, Spira ME (2011) Formation of Essential Ultrastructural Interface between Cultured Hippocampal Cells and Gold Mushroom-Shaped MEA- Toward "IN-CELL" Recordings from Vertebrate Neurons. Front Neuroeng 4:14.

Feng W, Cao Y, Patnaik D, Ramakrishnan N (2011) Temporal Data Mining for Neuroscience. In: GPU Computing Gems.

Ferrández JM, Lorente V, Garrigós J, Fernandez E (2011) Image Coding for Robotic Guidance Using Neuroblastoma Cultures. Majlesi Journal of Electrical Engineering 5.

Fuchsberger K, Goff AL, Gambazzi L, Toma FM, Goldoni A, Giugliano M, Stelzle M, Prato M (2011) Multiwalled carbon-nanotube-functionalized microelectrode arrays fabricated by microcontact printing: platform for studying chemical and electrical neuronal signaling. Small 7:524-530.

Geissler M, Faissner A (2011) A new indirect co-culture set up of mouse hippocampal neurons and cortical astrocytes on microelectrode arrays. J Neurosci Methods 204:262-272.

Ghezzi D (2011) Coupling MEA Recordings and Optical Stimulation: New Optoelectronic Biosensors. In: Optoelectronics – Devices and Applications.

Goyal G, Nam Y (2011) Neuronal Micro-culture Engineering by Microchannel Devices of Cellular Scale Dimensions. Biomed Eng Lett 1:89-98.

Kanagasabapathi TT, Ciliberti D, Martinoia S, Wadman WJ, Decre MM (2011) Dual-compartment neurofluidic system for electrophysiological measurements in physically segregated and functionally connected neuronal cell culture. Front Neuroeng 4:13.

Mourot A, Kienzler MA, Banghart MR, Fehrentz T, Huber FME, Stein M, Kramer RH, Trauner D (2011) Tuning Photochromic Ion Channel Blockers. ACS Chemical Neuroscience.

Nam Y, Wheeler BC (2011) In vitro microelectrode array technology and neural recordings. Crit Rev Biomed Eng 39:45-61.

Novellino A, Chiappalone M, Tessadori J, D'Angelo P, Defranchi E, Martinoia S (2011) Bioartificial Brains and Mobile Robots In: Mobile Robots - Control Architectures, Bio-Interfacing, Navigation, Multi Robot Motion Planning and Operator Training (Będkowski J, ed): InTech.

Pan L, Alagapan S, Franca E, Brewer GJ, Wheeler BC (2011) Propagation of action potential activity in a predefined microtunnel neural network. J Neural Eng 8:046031.

Pfeiffer T, Kraushaar U, Dufer M, Schonecker S, Haspel D, Gunther E, Drews G, Krippeit-Drews P (2011) Rapid functional evaluation of beta-cells by extracellular recording of membrane potential oscillations with microelectrode arrays. Pflugers Arch 462:835-840.

Raoux M, Bornat Y, Quotb A, Catargi B, Renaud S, Lang J (2011) Non-invasive long-term and real-time analysis of endocrine cells on micro-electrode arrays. J Physiol.

Ryynänen T, Kujala V, Ylä-Outinen L, Korhonen I, Tanskanen JMA, Kauppinen P, Aalto-Setälä K, Hyttinen J, Kerkelä E, Narkilahti S, Lekkala J (2011) All Titanium Microelectrode Array for Field Potential Measurements from Neurons and Cardiomyocytes—A Feasibility Study. Micromachines 2:394-409.

Saenz Cogollo JF, Tedesco M, Martinoia S, Raiteri R (2011) A new integrated system combining atomic force microscopy and micro-electrode array for measuring the mechanical properties of living cardiac myocytes. Biomed Microdevices 13:613-621.

Shein-Idelson M, Ben-Jacob E, Hanein Y (2011) Engineered neuronal circuits: a new platform for studying the role of modular topology. Front Neuroeng 4:10.

Urbanova V, Li Y, Vytras K, Yvert B, Kuhn A (2011) Macroporous microelectrode arrays for measurements with reduced noise. Journal of Electroanalytical Chemistry 656.

Wallach A, Eytan D, Gal A, Zrenner C, Marom S (2011) Neuronal Response Clamp. Frontiers in Neuroengineering 4.

Wei P, Taylor R, Ding Z, Chung C, Abilez OJ, Higgs G, Pruitt BL, Ziaie B (2011) Stretchable microelectrode array using room-temperature liquid alloy interconnects. JOURNAL OF MICROMECHANICS AND MICROENGINEERING 21:8pp.

Zeck G, Lambacher A, Fromherz P (2011) Axonal transmission in the retina introduces a small dispersion of relative timing in the ganglion cell population response. PLoS ONE 6:e20810.

Arnson HA, Fu X, Holy TE (2010) Multielectrode array recordings of the vomeronasal epithelium. J Vis Exp.

Asfour H, et al. (2010) Low frequency impedance spectroscopy of cell monolayers using the four-electrode method. Journal of Physics: Conference Series 224:012085.

Baker M (2010) From promising to practical: tools to study networks of neurons. Nat Meth 7:877-883.

Blau A, Murr A, Wolff S, Sernagor E, Medini P, Iurilli G, Ziegler C, Benfenati F (2010) Flexible, all-polymer microelectrode arrays for the capture of cardiac and neuronal signals. Biomaterials.

Bologna LL, Pasquale V, Garofalo M, Gandolfo M, Baljon PL, Maccione A, Martinoia S, Chiappalone M (2010) Investigating neuronal activity by SPYCODE multi-channel data analyzer. Neural Netw 23:685-697.

Bornat Y, Raoux M, Boutaib Y, Morin FO, Charpentier G, Lang J, Renaud S (2010) Detection of electrical activity of pancreatic ß-cells using micro-electrode arrays. Proceedings 5th IEEE Int. Symposium on Electronic Design, Test & Applications.

Braeken D, Prodanov D (2010) New trends and challenges in the development of microfabricated probes for recording and stimulating of excitable cells. In: New Developments in Biomedical Engineering.

Grossman N, Poher V, Grubb MS, Kennedy GT, Nikolic K, McGovern B, Berlinguer Palmini R, Gong Z, Drakakis EM, Neil MA, Dawson MD, Burrone J, Degenaar P (2010) Multi-site optical excitation using ChR2 and micro-LED array. J Neural Eng 7:16004.

Hai A, Shappir J, Spira ME (2010) In-cell recordings by extracellular microelectrodes. Nat Methods 7:200-202.

Hai A, Shappir J, Spira ME (2010) Long-term, multi-site, parallel, in-cell recording and stimulation by an array of extracellular microelectrodes. J Neurophysiol.

Johnstone AF, Gross GW, Weiss DG, Schroeder OH, Gramowski A, Shafer TJ (2010) Microelectrode arrays: A physiologically based neurotoxicity testing platform for the 21st century. Neurotoxicology.

Kim JH, Kang G, Nam Y, Choi YK (2010) Surface-modified microelectrode array with flake nanostructure for neural recording and stimulation. Nanotechnology 21:85303.

Krumin M, Reutsky I, Shoham S (2010) Correlation-based analysis and generation of multiple spike trains using hawkes models with an exogenous input. Front Comput Neurosci 4:147.

Liu Q, Ye W, Xiao L, Du L, Hu N, Wang P (2010) Extracellular potentials recording in intact olfactory epithelium by microelectrode array for a bioelectronic nose. Biosens Bioelectron.

Mennerick S, Chisari M, Shu HJ, Taylor A, Vasek M, Eisenman LN, Zorumski CF (2010) Diverse voltage-sensitive dyes modulate GABAA receptor function. J Neurosci 30:2871-2879.

Shein Idelson M, Ben-Jacob E, Hanein Y (2010) Innate synchronous oscillations in freely-organized small neuronal circuits. PLoS ONE 5:e14443.

Shew WL, Bellay T, Plenz D (2010) Simultaneous multi-electrode array recording and two-photon calcium imaging of neural activity. J Neurosci Methods.

Warwick K, Xydas D, Nasuto SJ, Becerra VM, Hammond MW, Downes JH, Marshall S, Whalley BJ (2010) Controlling a mobile robot with a biological brain. Defence Science Journal 60

Zrenner C, Eytan D, Wallach A, Thier P, Marom S (2010) A generic framework for real-time multi-channel neuronal signal analysis, telemetry control, and sub-millisecond latency feedback generation. Front Neurosci 4:173.

Al-Gayem Q, Richardson A, Burd N (2009) Built-in Test Solutions for the Electrode Structures in Bio-Fluidic Microsystems. In: European Test Symposium.

Berdondini L, Massobrio P, Chiappalone M, Tedesco M, Imfeld K, Maccione A, Gandolfo M, Koudelka-Hep M, Martinoia S (2009) Extracellular recordings from locally dense microelectrode arrays coupled to dissociated cortical cultures. J Neurosci Methods 177:386-396.

Blau A, Neumann T, Ziegler C, Benfenati F (2009) Replica-moulded polydimethylsiloxane culture vessel lids attenuate osmotic drift in long-term cell cultures. Journal of Biosciences 34.

Delivopoulos E, Murray AF, MacLeod NK, Curtis JC (2009) Guided growth of neurons and glia using microfabricated patterns of parylene-C on a SiO2 background. Biomaterials 30:2048-2058.

Dworak BJ, Wheeler BC (2009) Novel MEA platform with PDMS microtunnels enables the detection of action potential propagation from isolated axons in culture. Lab Chip 9:404-410.

Gawad S, Giugliano M, Heuschkel M, Wessling B, Markram H, Schnakenberg U, Renaud P, Morgan H (2009) Substrate arrays of iridium oxide microelectrodes for in vitro neuronal interfacing. Front Neuroengineering 2:1.

Haiss F, Butovas S, Schwarz C (2009) A miniaturized chronic microelectrode drive for awake behaving head restrained mice and rats. J Neurosci Methods.

Jungblut M, Knoll W, Thielemann C, Pottek M (2009) Triangular neuronal networks on microelectrode arrays: an approach to improve the properties of low-density networks for extracellular recording. Biomed Microdevices.

Kang G, Lee JH, Lee CS, Nam Y (2009) Agarose microwell based neuronal micro-circuit arrays on microelectrode arrays for high throughput drug testing. Lab Chip 9:3236-3242.

Mahlstedt MM, Anderson D, Sharp JS, McGilvray R, Munoz MD, Buttery LD, Alexander MR, Rose FR, Denning C (2009) Maintenance of pluripotency in human embryonic stem cells cultured on a synthetic substrate in conditioned medium. Biotechnol Bioeng.

Massobrio P, Tedesco M, Giachello C, Ghirardi M, Fiumara F, Martinoia S (2009) Helix neuronal ensembles with controlled cell type composition and placement develop functional polysynaptic circuits on Micro-Electrode Arrays. Neurosci Lett.

Mok SY, Lim YM, Goh SY (2009) A device to facilitate preparation of high-density neural cell cultures in MEAs. J Neurosci Methods 179:284-291.

Muratore R, Lamanna J, Szulman E, Kalisz A, Lamprecht M, Simon M, Yu Z, Xu N, Morrison B, 3rd (2009) Bioeffective Ultrasound at Very Low Doses:

Reversible Manipulation of Neuronal Cell

Morphology and Function in Vitro. 8th International Symposium on Therapeutic Ultrasound.

Ribeiro P, Simonotto J, Kaiser M, Silva F (2009) Parallel calculation of multi-electrode array correlation networks. J Neurosci Methods.

Rousseau L, Joucla S, Lissorgues G, Yvert B (2009) Microfabrication of new microelectrode arrays equipped with a ground surface configuration for focal neural microstimulation. J Micromech Microeng 19.

Shoval A, Adams C, David-Pur M, Shein M, Hanein Y, Sernagor E (2009) Carbon nanotube electrodes for effective interfacing with retinal tissue. Front Neuroengineering 2:4.

Ahuja AK, Behrend MR, Kuroda M, Humayun MS, Weiland JD (2008) An in vitro model of a retinal prosthesis. IEEE Trans Biomed Eng 55:1744-1753.

Ariano P, Lo Giudice A, Marcantoni A, Vittone E, Carbone E, Lovisolo D (2008) A diamond-based biosensor for the recording of neuronal activity. Biosens Bioelectron.

Brewer GJ, Boehler MD, Jones TT, Wheeler BC (2008) NbActiv4 medium improvement to Neurobasal/B27 increases neuron synapse densities and network spike rates on multielectrode arrays. J Neurosci Methods 170:181-187.

Bull L, Budd A, Stone C, Uroukov I, de Lacy Costello B, Adamatzky A (2008) Towards unconventional computing through simulated evolution: control of nonlinear media by a learning classifier system. Artif Life 14:203-222.

Chao ZC, Bakkum DJ, Potter SM (2008) Shaping embodied neural networks for adaptive goal-directed behavior. PLoS Comput Biol 4:e1000042.

Dockendorf KP, Park I, He P, Principe JC, Demarse TB (2008) Liquid state machines and cultured cortical networks: The separation property. Biosystems.

Escola R, Pouzat C, Chaffiol A, Yvert B, Magnin IE, Guillemaud R (2008) SIMONE: a realistic neural network simulator to reproduce MEA-based recordings. IEEE Trans Neural Syst Rehabil Eng 16:149-160.

Gabriel G, Gomez-Martinez R, Villa R (2008) Single-walled carbon nanotubes deposited on surface electrodes to improve interface impedance. Physiol Meas 29:S203-212.

Ghezzi D, Menegon A, Pedrocchi A, Valtorta F, Ferrigno G (2008) A Micro-Electrode Array device coupled to a laser-based system for the local stimulation of neurons by optical release of glutamate. J Neurosci Methods.

Hosp JA, Molina-Luna K, Hertler B, Atiemo CO, Stett A, Luft AR (2008) Thin-film epidural microelectrode arrays for somatosensory and motor cortex mapping in rat. J Neurosci Methods 172:255-262.

Huang Y, Li X, Li Y, Xu Q, Lu Q, Liu Q (2008) An integrative analysis platform for multiple neural spike train data. J Neurosci Methods 172:303-311.

Kloss D, Fischer M, Rothermel A, Simon JC, Robitzki AA (2008) Drug testing on 3D in vitro tissues trapped on a microcavity chip. Lab Chip 8:879-884.

Kloss D, Kurz R, Jahnke HG, Fischer M, Rothermel A, Anderegg U, Simon JC, Robitzki AA (2008) Microcavity array (MCA)-based biosensor chip for functional drug screening of 3D tissue models. Biosens Bioelectron 23:1473-1480.

Meier R, Egert U, Aertsen A, Nawrot MP (2008) FIND--a unified framework for neural data analysis. Neural Netw 21:1085-1093.

Moulin C, Gliere A, Barbier D, Joucla S, Yvert B, Mailley P, Guillemaud R (2008) A new 3-D finite-element model based on thin-film approximation for microelectrode array recording of extracellular action potential. IEEE Trans Biomed Eng 55:683-692.

Nam Y, Brown EA, Ross JD, Blum RA, Wheeler BC, Deweerth SP (2008) A retrofitted neural recording system with a novel stimulation IC to monitor early neural responses from a stimulating electrode. J Neurosci Methods.

Rodger C, Fong A, ..., Tai Y (2008) Flexible parylene-based multielectrode array technology for high-density neural stimulation and recording. Sensors and Actuators B 132.

Shein M, Greenbaum A, Gabay T, Sorkin R, David-Pur M, Ben-Jacob E, Hanein Y (2008) Engineered neuronal circuits shaped and interfaced with carbon nanotube microelectrode arrays. Biomed Microdevices.

Stummann TC, Wronski M, Sobanski T, Kumpfmueller B, Hareng L, Bremer S, Whelan MP (2008) Digital movie analysis for quantification of beating frequencies, chronotropic effects, and beating areas in cardiomyocyte cultures. Assay Drug Dev Technol 6:375-385.

Bontorin G, Renaud S, Garenne A, Alvado L, Le Masson G, Tomas J (2007) A real-time closed-loop setup for hybrid neural networks. Conf Proc IEEE Eng Med Biol Soc 1:3004-3007.

Gabay T, Ben-David M, Kalifa I, Sorkin R, Abrams ZR, Ben-Jacob E, Hanein Y (2007) Electro-chemical and biological properties of carbon nanotube based multi-electrode arrays. Nanotechnology 18:035201.

Leisgen C, Kuester M, Methfessel C (2007) The Roboocyte: Automated Electrophysiology Based on Xenopus Oocytes In: Patch Clamp Methods and Protocols (Molnar P, ed): Humana Press.

Macis E, Tedesco M, Massobrio P, Raiteri R, Martinoia S (2007) An automated microdrop delivery system for neuronal network patterning on microelectrode arrays. J Neurosci Methods 161:88-95.

Mazzatenta A, Giugliano M, Campidelli S, Gambazzi L, Businaro L, Markram H, Prato M, Ballerini L (2007) Interfacing neurons with carbon nanotubes: electrical signal transfer and synaptic stimulation in cultured brain circuits. J Neurosci 27:6931-6936.

Molina-Luna K, Buitrago MM, Hertler B, Schubring M, Haiss F, Nisch W, Schulz JB, Luft AR (2007) Cortical stimulation mapping using epidurally implanted thin-film microelectrode arrays. J Neurosci Methods 161:118-125.

Novellino A, D'Angelo P, Cozzi L, Chiappalone M, Sanguineti V, Martinoia S (2007) Connecting neurons to a mobile robot: an in vitro bidirectional neural interface. Computational Intelligence and Neuroscience.

Potter SM (2007) What Can AI Get from Neuroscience? In: 50 Years of AI (Lungarella M, ed), pp 174-185. Heidelberg: Springer Verlag.

Rajaraman S, Choi SO, Shafer RH, Ross JD, Vukasinovic J, Choi Y, DeWeerth SP, Glezer A, Allen MG (2007) Microfabrication technologies for a coupled three-dimensional microelectrode, microfluidic array. J Micromech Microeng 17:163–171.

Rutten WL, Ruardij TG, Marani E, Roelofsen BH (2007) Neural networks on chemically patterned electrode arrays: towards a cultured probe. Acta Neurochir Suppl 97:547-554.

Wrobel G, Zhang Y, Krause HJ, Wolters N, Sommerhage F, Offenhausser A, Ingebrandt S (2007) Influence of the first amplifier stage in MEA systems on extracellular signal shapes. Biosens Bioelectron 22:1092-1096.

Yu Z, McKnight TE, Ericson MN, Melechko AV, Simpson ML, Ill BM (2007) Vertically aligned carbon nanofiber arrays record electrophysiological signals from hippocampal slices. Nano Lett 7:2188-2195.

Berdondini L, Chiappalone M, vanderWala PD, Imfelda K, deRooija NF, Koudelka-Hepa M, Tedescob M, Martinoiab S, vanPeltd J, LeMassonc G, Garennec A (2006) A microelectrodearray (MEA) integrated with clustering structures for investigating in vitro neurodynamics in confined interconnected sub-populations of neurons. Sensors and Actuators B 114:530–541.

Chang JC, Brewer GJ, Wheeler BC (2006) Neuronal network structuring induces greater neuronal activity through enhanced astroglial development. J Neural Eng 3:217-226.

Cozzi L, D'Angelo P, Sanguineti V (2006) Encoding of time-varying stimuli in populations of cultured neurons. Biol Cybern 94:335-349.

Egert U (2006) NETWORKS ON CHIPS: Spatial and temporal activity dynamics of functional networks in brain slices and cardiac tissue. In.

Fejtl M, Stett A, Nisch W, Boven KH, Möller A (2006) On Micro-Electrode Array Revival: Its Development, Sophistication of Recording, and Stimulation. In: Advances in Network Electrophysiology (Taketani M, Baudry M, eds).

Gholmieh G, Soussou W, Han M, Ahuja A, Hsiao MC, Song D, Tanguay AR, Jr., Berger TW (2006) Custom-designed high-density conformal planar multielectrode arrays for brain slice electrophysiology. J Neurosci Methods 152:116-129.

Halbach M, Pillekamp F, Brockmeier K, Hescheler J, Muller-Ehmsen J, Reppel M (2006) Ventricular slices of adult mouse hearts--a new multicellular in vitro model for electrophysiological studies. Cell Physiol Biochem 18:1-8.

Kopanitsa MV, Afinowi NO, Grant SG (2006) Recording long-term potentiation of synaptic transmission by three-dimensional multi-electrode arrays. BMC Neurosci 7:61.

Liang PJ (2006) A New Method for Multiple Spike Train Analysis Based on Information Discrepancy. LNCS 4232, pp. 30–38, 2006.

Moulin C, Gliere A (2006) A new 3D finite element model of extracellular action potentials recording with a microelectrode in a tissue slice. Conf Proc IEEE Eng Med Biol Soc 1:603-606.

Nam Y, Branch DW, Wheeler BC (2006) Epoxy-silane linking of biomolecules is simple and effective for patterning neuronal cultures. Biosens Bioelectron 22:589-597.

Nam Y, Musick K, Wheeler BC (2006) Application of a PDMS microstencil as a replaceable insulator toward a single-use planar microelectrode array. Biomed Microdevices 8:375-381.

Petridou N, Plenz D, Silva AC, Loew M, Bodurka J, Bandettini PA (2006) Direct magnetic resonance detection of neuronal electrical activity. Proc Natl Acad Sci U S A 103:16015-16020.

Ravula SK, McClain MA, Wang MS, Glass JD, Frazier AB (2006) A multielectrode microcompartment culture platform for studying signal transduction in the nervous system. Lab Chip 6:1530-1536.

Rothermel A, Nieber M, Muller J, Wolf P, Schmidt M, Robitzki AA (2006) Real-time measurement of PMA-induced cellular alterations by microelectrode array-based impedance spectroscopy. Biotechniques 41:445-450.

Uroukov IS, Ma M, Bull L, Purcell WM (2006) Electrophysiological measurements in three-dimensional in vivo-mimetic organotypic cell cultures: preliminary studies with hen embryo brain spheroids. Neurosci Lett 404:33-38.

Wang GL, Liu X, Zhang PM, Liang PJ (2006) A New Method for Multiple Spike Train Analysis Based on Information Discrepancy. In: ICONIP 2006, Part I, (King I, ed).

Yu Z, Tsay C, Lacour SP, Wagner S, Morrison B, 3rd (2006) Stretchable Microelectrode Arrays A Tool for Discovering Mechanisms of Functional Deficits Underlying Traumatic Brain Injury and Interfacing Neurons with Neuroprosthetics.

Yu Z, Tsay C, Lacour SP, Wagner S, Morrison B (2006) Stretchable microelectrode arrays--a tool for discovering mechanisms of functional deficits underlying traumatic brain injury and interfacing neurons with neuroprosthetics. Conf Proc IEEE Eng Med Biol Soc Suppl:6732-6735.

Blanche TJ, Spacek MA, Hetke JF, Swindale NV (2005) Polytrodes: high-density silicon electrode arrays for large-scale multiunit recording. J Neurophysiol 93:2987-3000.

Chao ZC, Bakkum DJ, Wagenaar DA, Potter SM (2005) Effects of random external background stimulation on network synaptic stability after tetanization: a modeling study. Neuroinformatics 3:263-280.

Egert U (2005) Perforated Microelectrode Arrays Optimize Oxygen Availability and Signal-to-Noise Ratio in Brain Slice Recordings. MSTKongress.

Geis M (2005) Mustererkennung mit künstlichen neuralen Netzen am Beispiel von neuronenbasierten Biosensoren. Diplomarbeit an der Uni Mainz:69.

Pearce TM, Wilson JA, Oakes SG, Chiu SY, Williams JC (2005) Integrated microelectrode array and microfluidics for temperature clamp of sensory neurons in culture. Lab Chip 5:97-101.

Pillekamp F, Reppel M, Dinkelacker V, Duan Y, Jazmati N, Bloch W, Brockmeier K, Hescheler J, Fleischmann BK, Koehling R (2005) Establishment and characterization of a mouse embryonic heart slice preparation. Cell Physiol Biochem 16:127-132.

Potter SM, Wagenaar DA, DeMarse TB (2005) Closing the loop: Stimulation feedback systems for embodies MEA cultures. Springer:32.

Prado GR, Ross JD, DeWeerth SP, LaPlaca MC (2005) Mechanical trauma induces immediate changes in neuronal network activity. J Neural Eng 2:148-158.

Ruaro ME, Bonifazi P, Torre V (2005) Toward the neurocomputer: image processing and pattern recognition with neuronal cultures. IEEE Trans Biomed Eng 52:371-383.

Sadleir, FGrant S, DeMarse TB, Woo E, Lee S, Kim T, Oh S, Lee B, Seo J (2005) Study of MRI/MEA compatibility at 17.6 Tesla. IJBEM:4.

Stett A (2005) Perforated polimide microelectrode arrays for single-cell and tissue recording. MST-Kongress.

Wilms M, Eckhorn R (2005) Spatiotemporal receptive field properties of epiretinally recorded spikes and local electroretinograms in cats. BMC Neurosci 6:50.

Baruchi I, Ben-Jacob E (2004) Functional holography of recorded neuronal networks activity. Neuroinformatics 2:333-352.

Cozzi L, D'Angelo P, Ide AN, Novellino A, Sanguineti V (2004) Coding and decoding performance in a bi-directional neural interface between in vitro cultured neurons and a mobile robot.

Guenter E (2004) Microelectrode Array - based Biosensors. Screening:2.

Martinoia S, Sanguineti V, Cozzi L, Berdondini L, Van Pelt J, Tomas J, Le Masson G, Davide F (2004) Towards an embodied in vitro electrophysiology: the NeuroBIT project. Neurocomputing 58-60:1065-1072.

Meyer T, Boven KH, Gunther E, Fejtl M (2004) Micro-electrode arrays in cardiac safety pharmacology: a novel tool to study QT interval prolongation. Drug Saf 27:763-772.

Meyer T, Leisgen C, Gonser B, Gunther E (2004) QT-screen: high-throughput cardiac safety pharmacology by extracellular electrophysiology on primary cardiac myocytes. Assay Drug Dev Technol 2:507-514.

Nam Y, Chang JC, Wheeler BC, Brewer GJ (2004) Gold-coated microelectrode array with thiol linked self-assembled monolayers for engineering neuronal cultures. IEEE Trans Biomed Eng 51:158-165.

Nam Y, Wheeler BC (2004) Multichannel recording and stimulation of neuronal cultures grown on microstamped poly-D-lysin.

Pehl U, Leisgen C, Gampe K, Guenther E (2004) Automated higher-throughput compound screening on ion channel targets based on the Xenopus laevis oocyte expression system. Assay Drug Dev Technol 2:515-524.

Pfeffer L, Ide D, Stewart C, Plenz D (2004) A life support system for stimulation of and recording from rodent neuron networks grown on multi-electrode arrays. In: Computer-Based Medical Systems, 2004. CBMS 2004. Proceedings. 17th IEEE Symposium on.

Potter SM, Bakkum DJ, Shkolnik A, Bu-Ary G, Gamblen P, DeMarse TB (2004) Removing some "A" from AI: Embodied Cultured Networks. Springer:17.

Segev R, Baruchi I, Hulata E, Ben-Jacob E (2004) Hidden neuronal correlations in cultured networks. Phys Rev Lett 92:118102.

Vato A, Bonzano L, Chiappalone M, Cicero S, Morabito F, Novellina A, Stillo G (2004) Spike manager: a new tool for spontaneous and evoked neuronal networks activity characterization. Neurocomputing:9.

Wagenaar DA, Potter SM (2004) A versatile all-channel stimulator for electrode arrays, with real-time control. J Neural Eng 1:39-45.

Heuschkel MO (2003) Multi-electrode Array Biochips for Electrophysiology. Future Drug Discovery:4.

Jimbo Y, Kasai N, Torimitsu K, Tateno T, Robinson HP (2003) A system for MEA-based multisite stimulation. IEEE Trans Biomed Eng 50:241-248.

Potter SM, DeMarse TB, Wagenaar A, Madhavan R (2003) Long-Term Bidirectional Neuron Interfaces for Robotic Control, and In Vitro Learning Studies. Proceedings of the IEEE-EMBS:4.

Stett A (2003) New-generation MEA Technology: improving the interface to physiological function. SIMEA:35.

Stett A, Egert U, Guenther E, Hofmann F, Meyer T, Nisch W, Haemmerle H (2003) Biological application of microelectrode arrays in drug discovery and basic research. Anal Bioanal Chem 377:486-495.

van Bergen A, Papanikolaou T, Schuker A, Moller A, Schlosshauer B (2003) Long-term stimulation of mouse hippocampal slice culture on microelectrode array. Brain Res Brain Res Protoc 11:123-133.

Wang X, Li M (2003) Automated electrophysiology: high throughput of art. Assay Drug Dev Technol 1:695-708.

Zhang P, Wu J, Zhou Y, Liang PJ, Yuan J (2003) Spike sorting based on automatic template reconstructing with a partial solution to the overlapping problem. Journal of Neuroscience Methods:11.

Feld Y, Melamed-Frank M, Kehat I, Tal D, Marom S, Gepstein L (2002) Electrophysiological modulation of cardiomyocytic tissue by transfected fibroblasts expressing potassium channels: a novel strategy to manipulate excitability. Circulation 105:522-529.

Heuschkel MO, Fejtl M, Raggenbass M, Bertrand D, Renaud P (2002) A three-dimensional multi-electrode array for multi-site stimulation and recording in acute brain slices. J Neurosci Methods 114:135-148.

Segev R, Benveniste M, Hulata E, Cohen N, Palevski A, Kapon E, Shapira Y, Ben-Jacob E (2002) Long term behavior of lithographically prepared in vitro neuronal networks. Phys Rev Lett 88:118102.

Wagenaar DA, Potter SM (2002) Real-time multi-channel stimulus artifact suppression by local curve fitting. J Neurosci Methods 120:113-120.

Potter SM, DeMarse TB (2001) A new approach to neural cell culture for long-term studies. J Neurosci Methods 110:17-24.

Potter SM, Lukina N, Wu Y, Longmuir K (2001) Multi-side two-photon imaging of neurons on multi-electrode arrays. Proceeding of SPIE:7.

Bucher V (2000) Light-adressed sub-um electrodes for extracellular recording and stimulation of excitable cells. Microelectronic Engineering:8.

Ziegler C (2000) Cell-based biosensors. Fresenius J Anal Chem 366:552-559.