Innovations in Electrophysiology




The ME2100-System is a tethered in vivo recording system. It is the complete setup for anesthetized/head-fixed animals, including everything you need for your experiment.

The system consists of a signal collector unit (MCS-SCU) for up to four headstages, which also contains a connector for high power LEDs. The signal collector is connected via eSATA cable to the interface board. Up to two signal collectors can be connected to one MCS-IFB 3.0 multiboot interface board. Headstages have 32 recording channels plus ground and reference inputs. Amplifier, stimulators and A/D converters are all directly on the headstage, which allows low-noise, high quality data acquisition.

The stimulator units can be connected by software command to any of the recording channels, or to a connector for an external stimulation electrode, which is also located at the headstage. Each of the 32 channels can be used for recording or stimulation, whereas 2 channels can be used for external stimulation electrodes as well.

Key Features

  • Up to eight 32 channel headstages
  • Sampling with up to 50 kHz per channel
  • 24 bit resolution
  • Filter bandwidth adjustable via software
  • Integrated stimulation possible on each electrode with blanking feature
  • Programmable output for optical stimulation


As part of the system, the MCS-IFB 3.0 Multiboot is a new interface board generation which is able to receive data from a MEA2100-Headstage, a Multiwell-MEA-Headstage, a CMOS-MEA5000-Headstage, a MCS-SCU or a W2100-Receiver. This makes cost-effective combinations with only one interface board and multiple recording systems possible. You can establish for example your experiments on 60 or 120 electrodes with the MEA2100-System, then add the Multiwell-MEA-Headstage and start high-throughput screening. It's also possible to use the same interface board for in vitro MEA experiments and tethered / wireless in vivo recordings. This leaves you with even more flexibility in switching between possible configurations for your specific research needs.

Key features:

  • Real-time signal detection and feedback
  • Freely programmable DSP
  • Multiple inputs/outputs, including digital, analog, and audio
  • SuperSpeed USB 3.0 ports


Read more technical specifications