• sales [at] multichannelsystems [dot] com
  • phone +49 7121 9092525

www.multichannelsystems.com

Innovations in Electrophysiology

Xenopus Oocyte Research

Oocytes of the toad Xenopus laevis are widely used as an expression system for ion channels, transporters and receptors in drug development.

Until now, the low throughput of electrophysiology has prevented its use for secondary functional screening of drug targets.

Multi Channel Systems is proud to present you three helpful robots to automate all necessary tasks:

  • Automated injection with the Roboinject:
    A fully automated robot for compound injection into oocytes, eggs, and embryos using industry standard 96, 384, as well as custom well plates.
  • Automated drug screening with the Roboocyte:
    Sequential two-electrode voltage clamp (TEVC) recording in oocytes, classical perfusion of compounds.
  • Automated drug screening with the HiClamp:
    Sequential two-electrode voltage clamp (TEVC) recording in oocytes, non-destructive usage of small compound volumes.
Roboinject

Roboinject logo

Fully-automated Roboinject system for automated injection of RNA, DNA or other samples into Xenopus oocytes or cells of similar size. Complete with Roboinject robot, Roboinject software, and accessories.

Key features:

  • Optimized throughput of experiments
  • Automated, high-quality TEVC recording  from 96 oocytes without supervision
  • Flexible design of automated recording sequences
  • Automated compound application
  • Automated cell wash
  • Manual recording mode

On YouTube:

Roboocyte2

Roboocyte2 logo

Fully-automated Roboocyte2 system for screening of ligand-gated and voltage-gated ion channels, as well as electrogenic transporters based on the standard Xenopus oocyte expression system. Complete with Roboocyte2 robot, 12-channel perfusion system, data acquisition and analysis software package, computer, and accessories.

Key features:

  • Optimized throughput of experiments
  • Automated, high-quality TEVC recording  from 96 oocytes without supervision
  • Flexible design of automated recording sequences
  • Automated compound application
  • Automated cell wash
  • Manual recording mode

HiClamp

HiClamp logo

Automated Voltage-Clamp Screening System for Xenopus laevis oocytes. Complete with HiClamp robot, USB video camera, laptop computer with installed HiClamp software, accessories, and consumables.