Innovations in Electrophysiology

Dissociated cell cultures, cortex

Burley R, Harvey JRM (2021) Multielectrode Arrays. In: Patch Clamp Electrophysiology: Methods and Protocols (Dallas M, Bell D, eds), pp 109-132. New York, NY: Springer US.

Milligan CJ, Pachernegg S (2021) Utilising Automated Electrophysiological Platforms in Epilepsy Research. In: Patch Clamp Electrophysiology: Methods and Protocols (Dallas M, Bell D, eds), pp 133-155. New York, NY: Springer US.

Susloparova A, Halliez S, Begard S, Colin M, Buée L, Pecqueur S, Alibart F, Thomy V, Arscott S, Pallecchi E, Coffinier Y (2021) Low impedance and highly transparent microelectrode arrays (MEA) for in vitro neuron electrical activity probing. Sensors and Actuators B: Chemical 327:128895.

Tinarelli F, Ivanova E, Colombi I, Barini E, Balzani E, Garcia CG, Gasparini L, Chiappalone M, Kelsey G, Tucci V (2021) Cell-cell coupling and DNA methylation abnormal phenotypes in the after-hours mice. Epigenetics Chromatin 14:1.

Alloisio S, Clericuzio M, Nobile M, Salis A, Damonte G, Canali C, Fortuna-Perez AP, Cornara L, Burlando B (2020) Cannabis-like activity of Zornia latifolia Sm. detected in vitro on rat cortical neurons: major role of the flavone syzalterin. Drug Chem Toxicol:1-13.

Armada-Moreira A, Coelho JE, Lopes LV, Sebastião AM, Städler B, Vaz SH (2020) Multicompartment Microreactors Prevent Excitotoxic Dysfunctions In Rat Primary Cortical Neurons. Adv Biosyst:e2000139.

Badman RP, Moore SL, Killian JL, Feng T, Cleland TA, Hu F, Wang MD (2020) Dextran-coated iron oxide nanoparticle-induced nanotoxicity in neuron cultures. Sci Rep 10:11239.

Ciba M, Bestel R, Nick C, de Arruda GF, Peron T, Henrique CC, Costa LDF, Rodrigues FA, Thielemann C (2020) Comparison of Different Spike Train Synchrony Measures Regarding Their Robustness to Erroneous Data from Bicuculline-Induced Epileptiform Activity. Neural Comput:1-25.

Cornara L, Ambu G, Trombetta D, Denaro M, Alloisio S, Frigerio J, Labra M, Ghimire G, Valussi M, Smeriglio A (2020) Comparative and Functional Screening of Three Species Traditionally used as Antidepressants: Valeriana officinalis L., Valeriana jatamansi Jones ex Roxb. and Nardostachys jatamansi (D.Don) DC. Plants (Basel) 9.

Del Pino I, Tocco C, Magrinelli E, Marcantoni A, Ferraguto C, Tomagra G, Bertacchi M, Alfano C, Leinekugel X, Frick A, Studer M (2020) COUP-TFI/Nr2f1 Orchestrates Intrinsic Neuronal Activity during Development of the Somatosensory Cortex. Cereb Cortex.

Dominguez-Morales JP, Buccelli S, Gutierrez-Galan D, Colombi I, Jimenez-Fernandez A, Chiappalone M (2020) Real-time detection of bursts in neuronal cultures using a Neuromorphic Auditory Sensor and Spiking Neural Networks. bioRxiv:2020.2005.2020.105593.

Frega M, Selten M, Mossink B, Keller JM, Linda K, Moerschen R, Qu J, Koerner P, Jansen S, Oudakker A, Kleefstra T, van Bokhoven H, Zhou H, Schubert D, Nadif Kasri N (2020) Distinct Pathogenic Genes Causing Intellectual Disability and Autism Exhibit a Common Neuronal Network Hyperactivity Phenotype. Cell Rep 30:173-186 e176.

Guaraldi M, Lee S, Shea TB (2020) Synaptic Signals from Glutamate-Treated Neurons Induce Aberrant Post-Synaptic Signals in Untreated Neuronal Networks. TONEUJ 14.

Hakim-Eshed V, Boulos A, Cohen-Rosenzweig C, Yu-Taeger L, Ziv T, Kwon YT, Riess O, Phuc Nguyen HH, Ziv NE, Ciechanover A (2020) Site-specific ubiquitination of pathogenic huntingtin attenuates its deleterious effects. Proc Natl Acad Sci U S A.

Kharouf Q, Phillips AM, Bleakley LE, Morrisroe E, Oyrer J, Jia L, Ludwig A, Jin L, Nicolazzo JA, Cerbai E, Romanelli MN, Petrou S, Reid CA (2020) The hyperpolarization-activated cyclic nucleotide-gated 4 channel as a potential anti-seizure drug target. Br J Pharmacol.

Kumar R, Huang Y-T, Chen CC, Tzeng S-F, Chan CK (2020) Astrocytic regulation of synchronous bursting in cortical cultures: from local to global. bioRxiv:870915.

Mosbacher Y, Khoyratee F, Goldin M, Kanner S, Malakai Y, Silva M, Grassia F, Simon YB, Cortes J, Barzilai A, Levi T, Bonifazi P (2020) Toward neuroprosthetic real-time communication from in silico to biological neuronal network via patterned optogenetic stimulation. Sci Rep 10:7512.

Muzio L, Sirtori R, Gornati D, Eleuteri S, Fossaghi A, Brancaccio D, Manzoni L, Ottoboni L, Feo L, Quattrini A, Mastrangelo E, Sorrentino L, Scalone E, Comi G, Marinelli L, Riva N, Milani M, Seneci P, Martino G (2020) Retromer stabilization results in neuroprotection in a model of Amyotrophic Lateral Sclerosis. Nat Commun 11:3848.

Pemberton DK (2020) The Effects of the G Protein-Coupled Estrogen Receptor on Early Neuronal Development in Hippocampal and Cortical Neurons.

Poston RG, Murphy L, Rejepova A, Ghaninejad-Esfahani M, Segales J, Mulligan K, Saha RN (2020) Certain ortho-hydroxylated brominated ethers are promiscuous kinase inhibitors that impair neuronal signaling and neurodevelopmental processes. J Biol Chem 295:6120-6137.

Rienecker KDA, Poston RG, Segales JS, Saha RN (2020) Mild membrane depolarization in neurons induces immediate early gene transcription and acutely subdues responses to successive stimulus. bioRxiv:2020.2007.2023.217844.

Sambri I, Massa F, Gullo F, Meneghini S, Cassina L, Carraro M, Dina G, Quattrini A, Patanella L, Carissimo A, Iuliano A, Santorelli F, Codazzi F, Grohovaz F, Bernardi P, Becchetti A, Casari G (2020) Impaired flickering of the permeability transition pore causes SPG7 spastic paraplegia. EBioMedicine 61:103050.

Sardi S, Vardi R, Meir Y, Tugendhaft Y, Hodassman S, Goldental A, Kanter I (2020) Brain experiments imply adaptation mechanisms which outperform common AI learning algorithms. Sci Rep 10:6923.

Scanarotti C, Vernazza S, Tirendi S, Calzia D, Alloisio S, Novellino A, Panfoli I, Bassi AM (2020) Evaluation of Potential Risks to Human Health and Ecosystems During Exposure to Discarded Laboratory Chemical Mixtures by In Vitro Multimodel Approach. Applied In Vitro Toxicology 6:131-143.

Smeriglio A, Trombetta D, Alloisio S, Cornara L, Denaro M, Garbati P, Grassi G, Circosta C (2020) Promising in vitro antioxidant, anti-acetylcholinesterase and neuroactive effects of essential oil from two non-psychotropic Cannabis sativa L. biotypes. Phytother Res.

Valderhaug VD, Ramstad OH, van de Wijdeven R, Heiney K, Nichele S, Sandvig A, Sandvig I (2020) Structural and functional alterations associated with the LRRK2 G2019S mutation revealed in structured human neural networks. bioRxiv:2020.2005.2002.073726.

Vernekar VN, LaPlaca MC (2020) 3-D multi-electrode arrays detect early spontaneous electrophysiological activity in 3-D neuronal-astrocytic co-cultures. Biomedical Engineering Letters.

Wanzenboeck HD, Scholze P, Mika JK (2020) Imaging and Electrophysiology of Individual Neurites Functionally Isolated in Microchannels. In: Neurohistology and Imaging Techniques, Neuromethods (Pelc R, Walz W, Doucette J, eds). New York: Humana, New York, NY.

Wegrzyn D, Wegrzyn C, Tedford K, Fischer K-D, Faissner A (2020) Deletion of the Nucleotide Exchange Factor Vav3 Enhances Axonal Complexity and Synapse Formation but Tampers Activity of Hippocampal Neuronal Networks In Vitro. International Journal of Molecular Sciences 21:856.

Zhang X, Yeh FC, Ju H, Jiang Y, Quan GFW, VanDongen AMJ (2020) Familiarity detection and memory consolidation in cortical assemblies. eNeuro.

Buccelli S, Bornat Y, Colombi I, Ambroise M, Martines L, Pasquale V, Bisio M, Tessadori J, Nowak P, Grassia F, Averna A, Tedesco M, Bonifazi P, Difato F, Massobrio P, Levi T, Chiappalone M (2019) A neuroprosthetic system to restore neuronal communication in modular networks. bioRxiv:514836.

Choukairi Z, Hazzaz T, Lkhider M, Ferrandez JM, Fechtali T (2019) Effect of salvia Officinalis L. and Rosmarinus Officinalis L. leaves extracts on anxiety and neural activity. Bioinformation 16.

Datta Chaudhuri A, Dasgheyb RM, DeVine LR, Bi H, Cole RN, Haughey NJ (2019) Stimulus-dependent modifications in astrocyte-derived extracellular vesicle cargo regulate neuronal excitability. Glia 0.

del Pino I, Tocco C, Magrinelli E, Marcantoni A, Ferraguto C, Tomagra G, Alfano C, Leinekugel X, Frick A, Studer M (2019) Intrinsic neuronal excitability and spontaneous activity underlie cortical abnormalities upon Nr2f1/COUP-TFI deficiency. bioRxiv:728402.

Frega M, Linda K, Keller JM, Gümüş-Akay G, Mossink B, van Rhijn J-R, Negwer M, Gunnewiek TK, Foreman K, Kompier N, Schoenmaker C, van den Akker W, Oudakker A, Zhou H, Kleefstra T, Schubert D, van Bokhoven H, Kasri NN (2019) Neuronal network dysfunction in a human model for Kleefstra syndrome mediated by enhanced NMDAR signaling. bioRxiv:585596.

Gao F, Gao K, He C, Liu M, Wan H, Wang P (2019) Multi-site dynamic recording for Aβ oligomers-induced Alzheimer's disease in vitro based on neuronal network chip. Biosensors and Bioelectronics.

Gortz P, Henning U, Theiss S, Lange-Asschenfeldt C (2019) Effect fingerprints of antipsychotic drugs on neural networks in vitro. J Neural Transm (Vienna).

Heiney K, Huse Ramstad O, Sandvig I, Sandvig A, Nichele S (2019) Assessment and manipulation of the computational capacity of in vitro neuronal networks through criticality in neuronal avalanches.

Jackson MR, Loring KE, Homan CC, Thai MH, Maattanen L, Arvio M, Jarvela I, Shaw M, Gardner A, Gecz J, Shoubridge C (2019) Heterozygous loss of function of IQSEC2/Iqsec2 leads to increased activated Arf6 and severe neurocognitive seizure phenotype in females. Life Sci Alliance 2.

Jaudon F, Thalhammer A, Cingolani LA (2019) Correction of β3 integrin haplo-insufficiency by CRISPRa normalizes cortical network activity. bioRxiv:664706.

Köhler T (2019) Auswirkungen elektromagnetischer Strahlung auf die elektrophysiologischen Eigenschaften neuronaler und kardialer Zellnetzwerke Fachbereich Biologie

Maestrelli F, Landucci E, De Luca E, Nerli G, Bergonzi MC, Piazzini V, Pellegrini-Giampietro DE, Gullo F, Becchetti A, Tadini-Buoninsegni F, Francesconi O, Nativi C (2019) Niosomal Formulation of a Lipoyl-Carnosine Derivative Targeting TRPA1 Channels in Brain. Pharmaceutics 11.

Marcuzzo S, Terragni B, Bonanno S, Isaia D, Cavalcante P, Cappelletti C, Ciusani E, Rizzo A, Regalia G, Yoshimura N, Ugolini GS, Rasponi M, Bechi G, Mantegazza M, Mantegazza R, Bernasconi P, Minati L (2019) Hyperexcitability in Cultured Cortical Neuron Networks from the G93A-SOD1 Amyotrophic Lateral Sclerosis Model Mouse and its Molecular Correlates. Neuroscience 416:88-99.

Marta P, Ilaria C, Matteo F, Freschi A, Bandarabadi M, Andrea A, Encarnación BM, Adamantidis AR, Roberto A, Matteo C, Michela C, Valter T (2019) The paternally imprinted gene Snord116 regulates cortical neuronal activity. bioRxiv:809822.

Mateus J, Lopes C, Cerquido M, Leitao L, Leitao DC, Cardoso S, Ventura J, Aguiar P (2019) Improved in vitro electrophysiology using 3D-structured microelectrode arrays with a micro-mushrooms islets architecture capable of promoting topotaxis. J Neural Eng.

Mendis GDC, Berecki G, Morrisroe E, Pachernegg S, Li M, Varney M, Osborne PB, Reid CA, Halgamuge S, Petrou S (2019) Discovering the pharmacodynamics of conolidine and cannabidiol using a cultured neuronal network based workflow. Sci Rep 9:121.

Meng C, Yang X, Liu Y, Zhou Y, Rui J, Li S, Xu C, Zhuang Y, Lao J, Zhao X (2019) Decreased expression of lncRNA Malat1 in rat spinal cord contributes to neuropathic pain by increasing neuron excitability after brachial plexus avulsion. J Pain Res 12:1297-1310.

Miller SJ, Philips T, Kim N, Dastgheyb R, Chen Z, Hsieh YC, Daigle JG, Datta M, Chew J, Vidensky S, Pham JT, Hughes EG, Robinson MB, Sattler R, Tomer R, Suk JS, Bergles DE, Haughey N, Pletnikov M, Hanes J, Rothstein JD (2019) Molecularly defined cortical astroglia subpopulation modulates neurons via secretion of Norrin. Nat Neurosci 22:741-752.

Morrisroe E (2019) Multielectrode Arrays: A tool for modellig genetic epilepsy. FACULTY OF MEDICINE, DENTISTRY & HEALTH SCIENCES

Muzzi L, Hassink G, Levers M, Jansman M, Frega M, Hofmeijer J, van Putten M, le Feber J (2019) Mild stimulation improves neuronal survival in an in vitro model of the ischemic penumbra. J Neural Eng 17:016001.

Nguyen JT, Sahabandu D, Taishi P, Xue M, Jewett K, Dykstra-Aiello C, Roy S, Krueger JM (2019) The neuron-specific interleukin-1 receptor accessory protein alters emergent network state properties in Vitro. Neurobiology of Sleep and Circadian Rhythms 6:35-43.

Okujeni S, Egert U (2019) Self-organization of modular network architecture by activity-dependent neuronal migration and outgrowth. Elife 8.

Savarraj JP, Kelly KC, DeCoster MA (2019) Early glioma is associated with abnormal electrical events in cortical cultures. Med Biol Eng Comput.

Val-Calvo M, Álvarez-Sánchez JR, Alegre-Cortés J, de la Paz-López F, Ferrández-Vicente JM, Fernández-Jover E, Val-Calvo I (2019) Frequency variation analysis in neuronal cultures for stimulus response characterization. Neural Comput & Applic.

Van De Vijver S, Missault S, Van Soom J, Van Der Veken P, Augustyns K, Joossens J, Dedeurwaerdere S, Giugliano M (2019) The effect of pharmacological inhibition of Serine Proteases on neuronal networks in vitro. PeerJ 7:e6796.

Wülfing JM, Kumar SS, Boedecker J, Riedmiller M, Egert U (2019) Adaptive long-term control of biological neural networks with Deep Reinforcement Learning. Neurocomputing.

Xia Q, Nyberg T (2019) Photothermal Inhibition of Cortex Neurons Activity by Infrared Laser. World Congress on Medical Physics and Biomedical Engineering 2018:99-104.

Bar El Y, Kanner S, Barzilai A, Hanein Y (2018) Activity changes in neuron-astrocyte networks in culture under the effect of norepinephrine. PLoS ONE 13:e0203761.

Bar El Y, Kanner S, Barzilai A, Hanein Y (2018) Calcium imaging, MEA recordings and Immunostaining images dataset of Neuron-Astrocyte Networks in Culture under the Effect of Norepinephrine. Gigascience.

Capone C, Gigante G, Del Giudice P (2018) Spontaneous activity emerging from an inferred network model captures complex temporal dynamics of spiking data. arXiv

Caputo L (2018) Chemical and Biological study of natural substances active on the Central Nervous System. Dipartimento di Farmacia.

Casanova A, Bettamin L, Blatche MC, Mathieu F, Martin H, Gonzalez-Dunia D, Nicu L, Larrieu G (2018) Nanowire based bioprobes for electrical monitoring of electrogenic cells. J Phys Condens Matter 30:464001.

Chaudhuri AD, Dastgheyb RM, Yoo SW, Trout A, Talbot CC, Jr., Hao H, Witwer KW, Haughey NJ (2018) TNFalpha and IL-1beta modify the miRNA cargo of astrocyte shed extracellular vesicles to regulate neurotrophic signaling in neurons. Cell Death Dis 9:363.

El Khoueiry C, Moretti D, Renom R, Camera F, Orlacchio R, Garenne A, Poulletier de Gannes F, Poque-Haro E, Lagroye I, Veyret B, Lewis N (2018) DECREASED SPONTANEOUS ELECTRICAL ACTIVITY IN NEURONAL NETWORKS EXPOSED TO RADIOFREQUENCY 1800 MHZ SIGNALS. J Neurophysiol.

Frega M, Selten M, Mossink B, Keller JM, Linda K, Moerschen R, Qu J, Koerner P, Jansen S, Bijvank E, Oudakker A, Kleefstra T, van Bokhoven H, Zhou H, Schubert D, Nadif Kasri N (2018) Distinct pathogenic genes causing intellectual disability and autism exhibit overlapping effects on neuronal network development. bioRxiv.

Gaburro J, Bhatti A, Sundaramoorthy V, Dearnley M, Green D, Nahavandi S, Paradkar PN, Duchemin JB (2018) Zika virus-induced hyper excitation precedes death of mouse primary neuron. Virol J 15:79.

George JB, Abraham GM, Amrutur B, Sikdar SK (2018) Random Neuronal Networks show homeostatic regulation of global activity while showing persistent changes in specific connectivity paths to theta burst stimuli. Sci Rep 8:16568.

Georgopoulos AP, Tsilibary EC, Souto EP, James LM, Engdahl BE, Georgopoulos A (2018) Adverse effects of Gulf War Illness (GWI) serum on neural cultures and their prevention by healthy serum. Journal of Neurology & Neuromedicine 3:19-27.

Hadwen J, Schock S, Mears A, Yang R, Charron P, Zhang L, Xi HS, MacKenzie A (2018) Transcriptomic RNAseq drug screen in cerebrocortical cultures: toward novel neurogenetic disease therapies. Hum Mol Genet 27:3206-3217.

Hagman S, Makinen A, Yla-Outinen L, Huhtala H, Elovaara I, Narkilahti S (2018) Effects of inflammatory cytokines IFN-gamma, TNF-alpha and IL-6 on the viability and functionality of human pluripotent stem cell-derived neural cells. J Neuroimmunol.

Halawa I, Goldental A, Shirota Y, Kanter I, Paulus W (2018) Less Might Be More: Conduction Failure as a Factor Possibly Limiting the Efficacy of Higher Frequencies in rTMS Protocols. Front Neurosci 12:358.

Hassink GC, Raiss CC, Segers-Nolten IMJ, van Wezel RJA, Subramaniam V, le Feber J, Claessens M (2018) Exogenous alpha-synuclein hinders synaptic communication in cultured cortical primary rat neurons. PLoS ONE 13:e0193763.

Kuebler ES (2018) Harnessing the variability of neuronal activity School of Psychology, Faculty of Social Sciences PhD in Experimental Psychology.

le Feber J, Dummer A, Hassink GC, van Putten M, Hofmeijer J (2018) Evolution of Excitation-Inhibition Ratio in Cortical Cultures Exposed to Hypoxia. Front Cell Neurosci 12:183.

Lopes CDF, Mateus JC, Aguiar P (2018) Interfacing Microfluidics with Microelectrode Arrays for Studying Neuronal Communication and Axonal Signal Propagation. J Vis Exp.

Moskalyuk A, Kooy FR, Giugliano M (2018) Single-cell and neuronal network alterations in an in vitro model of Fragile X syndrome. bioRxiv.

Pastore VP, Massobrio P, Godjoski A, Martinoia S (2018) Identification of excitatory-inhibitory links and network topology in large-scale neuronal assemblies from multi-electrode recordings. PLoS Comput Biol 14:e1006381.

Perez-Gomez A, Cabrera-Garcia D, Warm D, Marini AM, Salas Puig J, Fernandez-Sanchez MT, Novelli A (2018) Selective Enhancement of Domoic Acid Toxicity in Primary Cultures of Cerebellar Granule Cells by Lowering Extracellular Na+ Concentration. Toxicol Sci 161:103-114.

Perez-Gomez A, Cabrera-Garcia D, Warm D, Marini AM, Salas Puig J, Fernandez-Sanchez MT, Novelli A (2018) From the Cover: Selective Enhancement of Domoic Acid Toxicity in Primary Cultures of Cerebellar Granule Cells by Lowering Extracellular Na+ Concentration. Toxicol Sci 161:103-114.

Piasetzky Y, Bisio M, Kanner S, Goldin M, Olivenboim M, Ben-Jacob E, Hanein Y, Chiappalone M, Barzilai A, Bonifazi P (2018) The emergence of dynamical instantaneous memory in the spontaneous activity of spatially confined neuronal assemblies in vitro. bioRxiv.

Poli D, Massobrio P (2018) High-frequency electrical stimulation promotes reshaping of the functional connections and synaptic plasticity in in vitro cortical networks. Phys Biol 15:06LT01.

Prakash M, Medendorp WE, Hochgeschwender U (2018) Defining parameters of specificity for bioluminescent optogenetic activation of neurons using in vitro multi electrode arrays (MEA). J Neurosci Res.

Saberi-Moghadam S, Simi A, Setareh H, Mikhail C, Tafti M (2018) In vitro Cortical Network Firing is Homeostatically Regulated: A Model for Sleep Regulation. Sci Rep 8:6297.

Sardi S, Vardi R, Goldental A, Sheinin A, Uzan H, Kanter I (2018) Adaptive nodes enrich nonlinear cooperative learning beyond traditional adaptation by links. Scientific Reports 8:5100.

Teppola H, Okujeni S, Linne M-L, Egert U (2018) AMPA, NMDA and GABAA receptor mediated network burst dynamics in cortical cultures in vitro. arXiv.

Van De Vijver S, Missault S, Van Soom J, Van der Veken P, Augustyns K, Joossens J, Dedeurwaerdere S, Giugliano M (2018) The Effect of Acute Pharmacological Inhibition of Urokinase Plasminogen Activator and Neuropsin Extracellular Proteases on Neuronal Networks in vitro. bioRxiv:263616.

Bourke JL, Quigley AF, Duchi S, O'Connell CD, Crook JM, Wallace GG, Cook MJ, Kapsa RMI (2017) Three-dimensional neural cultures produce networks that mimic native brain activity. Journal of Tissue Engineering and Regenerative Medicine:n/a-n/a.

Chan SC, Mok SY, Ng DW, Goh SY (2017) The role of neuron-glia interactions in the emergence of ultra-slow oscillations. Biol Cybern 111:459-472.

Dauth S, Maoz BM, Sheehy SP, Hemphill MA, Murty T, Macedonia MK, Greer AM, Budnik B, Parker KK (2017) Neurons derived from different brain regions are inherently different in vitro: a novel multiregional brain-on-a-chip. J Neurophysiol 117:1320-1341.

Dermutz H, Thompson-Steckel G, Forro C, de Lange V, Dorwling-Carter L, Voros J, Demko L (2017) Paper-based patterned 3D neural cultures as a tool to study network activity on multielectrode arrays. RSC Advances 7:39359-39371.

Fedorovich S, Hofmeijer J, van Putten MJ, le Feber J (2017) Reduced Synaptic Vesicle Recycling during Hypoxia in Cultured Cortical Neurons. Front Cell Neurosci 11:32.

Gertz ML, Baker Z, Jose S, Peixoto N (2017) Time-dependent Increase in the Network Response to the Stimulation of Neuronal Cell Cultures on Micro-electrode Arrays.e55726.

Kirischuk S, Sinning A, Blanquie O, Yang JW, Luhmann HJ, Kilb W (2017) Modulation of Neocortical Development by Early Neuronal Activity: Physiology and Pathophysiology. Front Cell Neurosci 11:379.

Kohler T, Wolfel M, Ciba M, Bochtler U, Thielemann C (2017) Terrestrial Trunked Radio (TETRA) exposure of neuronal in vitro networks. Environ Res 162:1-7.

Kuykendal M, Guvanasen G, Potter S, Grover M, DeWeerth S (2017) Closed-Loop Characterization of Neuronal Activation Using Electrical Stimulation and Optical Imaging. Processes 5:30.

Kuykendal M, Potter S, Grover M, DeWeerth S (2017) Targeted Stimulation Using Differences in Activation Probability across the Strength–Duration Space. Processes 5:14.

le Feber J, Erkamp N, van Putten M, Hofmeijer J (2017) Loss and recovery of functional connectivity in cultured cortical networks exposed to hypoxia. J Neurophysiol 118:394-403.

Mack CM, Hall DR, Herr DW, Shafer TJ (2017) Low and High-Frequency Field Potentials in Cortical Networks Exhibit Distinct Responses to Chemicals. The FASEB Journal 31:861.814.

Mendis GDC (2017) Detection of Phenotypic Network Signatures in Cultured Neuronal Networks. Department of Mechanical Engineering.

Okujeni S, Kandler S, Egert U (2017) Mesoscale architecture shapes initiation and richness of spontaneous network activity. J Neurosci.

Orenstein O, Keren H (2017) Development of Cortical Networks under Continuous Stimulation. Front Mol Neurosci 10:18.

Pasquale V, Martinoia S, Chiappalone M (2017) Stimulation triggers endogenous activity patterns in cultured cortical networks. Sci Rep 7:9080.

Pérez-Gómez A, Cabrera-García D, Warm D, Marini AM, Salas Puig J, Fernández-Sánchez MT, Novelli A (2017) Selective Enhancement of Domoic Acid Toxicity in Primary Cultures of Cerebellar Granule Cells by Lowering Extracellular Na+ Concentration. Toxicological Sciences:kfx201-kfx201.

Rojas Cifuentes CA, Tedesco M, Massobrio P, Marino A, Ciofani G, Martinoia S, Raiteri R (2017) Acoustic stimulation can induce a selective neural network response mediated by piezoelectric nanoparticles. J Neural Eng.

Sardi S, Vardi R, Sheinin A, Goldental A, Kanter I (2017) New Types of Experiments Reveal that a Neuron Functions as Multiple Independent Threshold Units. Sci Rep 7:18036.

Satuvuori E, Mulansky M, Bozanic N, Malvestio I, Zeldenrust F, Lenk K, Kreuz T (2017) Measures of spike train synchrony for data with multiple time scales. J Neurosci Methods 287:25-38.

Scarsi F, Tessadori J, Chiappalone M, Pasquale V (2017) Investigating the impact of electrical stimulation temporal distribution on cortical network responses. BMC Neurosci 18:49.

Simon DM, Charkhkar H, St John C, Rajendran S, Kang T, Reit R, Arreaga-Salas D, McHail DG, Knaack GL, Sloan A, Grasse D, Dumas TC, Rennaker RL, Pancrazio JJ, Voit WE (2017) Design and demonstration of an intracortical probe technology with tunable modulus. J Biomed Mater Res A 105:159-168.

Smeriglio A, Alloisio S, Raimondo FM, Denaro M, Xiao J, Cornara L, Trombetta D (2017) Essential oil of Citrus lumia Risso: Phytochemical profile, antioxidant properties and activity on the central nervous system. Food Chem Toxicol.

Ugbode CI, Smith I, Whalley BJ, Hirst WD, Rattray M (2017) Sonic hedgehog signalling mediates astrocyte crosstalk with neurons to confer neuroprotection. J Neurochem 142:429-443.

Valkki IA, Lenk K, Mikkonen JE, Kapucu FE, Hyttinen JAK (2017) Network-Wide Adaptive Burst Detection Depicts Neuronal Activity with Improved Accuracy. Front Comput Neurosci 11:40.

Vardi R, Goldental A, Sheinin A, Sardi S, Kanter I (2017) Fast reversible learning based on neurons functioning as anisotropic multiplex hubs. EPL (Europhysics Letters) 118:46002.

Vassallo A, Chiappalone M, De Camargos Lopes R, Scelfo B, Novellino A, Defranchi E, Palosaari T, Weisschu T, Ramirez T, Martinoia S, Johnstone AFM, Mack CM, Landsiedel R, Whelan M, Bal-Price A, Shafer TJ (2017) A multi-laboratory evaluation of microelectrode array-based measurements of neural network activity for acute neurotoxicity testing. Neurotoxicology 60:280-292.

Alagapan S, Franca E, Pan L, Leondopulos S, Wheeler BC, DeMarse TB (2016) Structure, Function, and Propagation of Information across Living Two, Four, and Eight Node Degree Topologies. Front Bioeng Biotechnol 4:15.

Bart Martens M, Frega M, Classen J, Epping L, Bijvank E, Benevento M, van Bokhoven H, Tiesinga P, Schubert D, Nadif Kasri N (2016) Euchromatin histone methyltransferase 1 regulates cortical neuronal network development. Sci Rep 6:35756.

Barykina NV, Subach OM, Doronin DA, Sotskov VP, Roshchina MA, Kunitsyna TA, Malyshev AY, Smirnov IV, Azieva AM, Sokolov IS, Piatkevich KD, Burtsev MS, Varizhuk AM, Pozmogova GE, Anokhin KV, Subach FV, Enikolopov GN (2016) A new design for a green calcium indicator with a smaller size and a reduced number of calcium-binding sites. Sci Rep 6:34447.

Berglund K, Tung JK, Higashikubo B, Gross RE, Moore CI, Hochgeschwender U (2016) Combined Optogenetic and Chemogenetic Control of Neurons. Methods Mol Biol 1408:207-225.

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