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Innovations in Electrophysiology

Webinars

Detecting Early Synaptic Failure in Prion Disease Using Organoid Models

Date (Berlin Time): Tue, Jun 02, 2026
Prion diseases are fatal neurodegenerative disorders marked by progressive synaptic dysfunction long before widespread neuronal loss becomes evident. Using both mouse models and human brain organoids, researchers are uncovering how prion replication disrupts synaptic transmission and connectivity at the earliest stages of disease, often well before significant prion accumulation or clinical symptoms appear.
 
In this webinar hosted by Simote Foliaki, PhD, we explore how these models reveal early synaptic deficits in both infectious and genetic prion disease, including during the prodromal phase. We'll also discuss why capturing these gradual, long-term changes requires electrophysiological approaches and technologies like Mesh MEA that are capable of monitoring neuronal activity over extended timeframes, providing critical insights into disease progression and new opportunities for early detection.

Organoid Meets Microelectrode Array (MEA) – Accelerating Drug Discovery and Development

Date (Berlin Time): Wed, Jan 24, 2024

In today’s fast paced research environment, drug testing, regulatory requirements, and alternative methods are at the forefront of neuroscience research. In this webinar, Dr. Sven Schönecker discusses the latest in 3D Mesh MEA’s, its ability for a more true-to-life system for studying organoids, and the versatility of the well-established MEA2100 system from Multi Channel Systems (MCS), an affiliate of Harvard Bioscience (HB).

Key Topics Include:

  • Why organoids? – Advancements and alternative models to support the 3R’s (replace, reduce, refine) of animal models
  • How did we get here? – Understand the challenges of 2D electrodes and the introduction of the 3D Mesh MEA
  • Benefits of the platform – Electrophysiology simplified…simple integration and flexibility using a universal, well-established platform
  • It’s all possible – Cell culture, slices, organoids, implantation, and beyond

Cardiac Research Using Microelectrode Array (MEA) Technology: Methodology Considerations and Best Practices to Optimize Recording

Date (Berlin Time): Wed, Sep 21, 2022

Join George Portugal, PhD for an overview of microelectrode array (MEA) technology used for cardiac research and some best practices for integrating this technique into your research.

Electrophysiology of Human Native Receptors in Neurological and Mental Disorders

Date (Berlin Time): Wed, Dec 08, 2021

Have a look at how Agenor Limon, PhD from the University of Texas Medical Branch and team have been looking at electrophysiological metrics of global synaptic E/I ratios in cortical brain regions of subjects that were affected by Alzheimer’s Disease and synaptic measurements in schizophrenia. How did automating processes with Roboocyte2 help in being more efficient and receiving better results?

Cellular Mechanisms Behind Alcohol Abuse and Binge Drinking Behavior

Date (Berlin Time): Wed, May 05, 2021

Exciting research looking at the cellular mechanisms of alcohol abuse and behavior using a combination of techniques including HEKA Patch Clamp for electrophysiology recordings, optogenetics, calcium imaging, and behavioral measurements.

Join Dr. Gilles Martin from the University of Massachusetts Medical School as he gives an overview of his recent research on the cellular mechanisms underlying alterations in brain regions caused by binge drinking that control behavior. Register through Inside Scientific to learn more about this fascinating research!

 

The Wonderful World of Scanning Electrochemical Microscopy (SECM)

Date (Berlin Time): Wed, Mar 10, 2021

SECM technique overview and applications related to material characterization, corrosion and batteries using HEKA ElProScan.

Join Dr. Janine Mauzeroll from McGill University as she gives an overview of her recent research on material characterization, corrosion and batteries using the ElProScan high-resolution electrochemical probe scanner.  Register through Inside Scientific to learn more about this fascinating research application!

 

Join us on Wednesday 10th of March at 11am ET/ 5pm CET

 

Reductions in Impulsivity in an Animal Model of Attention Deficit Hyperactivity Disorder (ADHD)

Date (Berlin Time): Tue, Feb 23, 2021

Impulsivity and treatment in ADHD mouse models using Panlab 5/9 hold box.

ADHD affects and estimated 2.8% of the global population. Dr. F. Scott Hall and his team are working to better understand impulsive behavior in genetic mouse models of ADHD. In his upcoming webinar, he will share his teams behavioral approach studying impulsive behavior associated with ADHD and common therapeutic strategies. Register today!

 

Join us on Tuesday 23rd of February at 11am ET/ 5pm CET

 

Multimodal Behavioral Assessment After Experimental Brain Trauma

Date (Berlin Time): Wed, Feb 03, 2021

Behavioral approaches to evaluate cognitive deficits in rats following traumatic brain injury using Coulbourn behavioral equipment.

Traumatic Brain injuries (TBI) affect over 2.8 million American’s each year. Dr. Corina Bondi and her team are working to better understand complex cognitive deficits following TBI in rat models. In her upcoming webinar, she will share her teams multimodal behavioral approaches that have helped to better understand cognitive impairments and more suitable therapeutic strategies.

 

Virtual Discussion: Remove Uncertainty with Precise, Reproducible Infusion Techniques in Neuroscience Research

Date (Berlin Time): Wed, Jan 20, 2021

Join us for this insightful one hour event, during which Pete Nadeau, Harvard Apparatus Global Fluidics Product Manager, will offer highlights of cutting-edge research in neuroscience with a focus on the essential role of syringe pumps in the success of this work. What to Expect:

Advancements in Research Virtual Discussion: Wireless and Tethered In Vivo Approaches for Neurological Recordings in Freely Moving Animals

Date (Berlin Time): Wed, Sep 30, 2020

Explore new possibilities in behavioral neuroscience research! Whether your in vivo recording preferences are wireless or tethered, this is one webinar you do not want to miss. Join MCS Application Specialist, George Portugal, to learn more about benefits of the W2100 and ME2100 recording systems from Multi Channel Systems.

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