Innovations in Electrophysiology




The ME2100-System is a tethered in vivo recording system. It is the complete setup for anesthetized/head-fixed animals, including everything you need for your experiment.

The system consists of a signal collector unit (MCS-SCU) for up to four headstages, which also contains a connector for up to four outputs for optical stimulation (optogenetics). The signal collector is connected via eSATA cable to the interface board. Up to two signal collectors can be connected to one IFB-C multiboot interface board. Headstages have 32 recording channels plus ground and reference inputs. Amplifier, stimulators and A/D converters are all directly on the headstage, which allows low-noise, high quality data acquisition.

The stimulator units can be connected by software command to any of the recording channels, or to a connector for an external stimulation electrode, which is also located at the headstage. Each of the 32 channels can be used for recording or stimulation, whereas 2 channels can be used for external stimulation electrodes as well.

ME2100-System-8-fold With a multifold ME2100-System up to two signal collectors can be connected to one interface board, thereby creating a system with 8 headstages for parallel recordings.


Key Features

  • Up to eight 32 channel headstages
  • Sampling with up to 50 kHz per channel
  • 24 bit resolution
  • Filter bandwidth adjustable via software
  • Integrated stimulation possible on each electrode with blanking feature
  • Programmable output for optical stimulation


MCS-InterfaceBoard-3.0-Multiboot IFB-C

As part of the system, the IFB-C multiboot is a new interface board generation which is able to receive data from a MEA2100(-Mini)-Headstage, a Multiwell-MEA-Headstage, a CMOS-MEA5000-Headstage, a MEA2100-Beta-Screen-Headstage, a ME2100-Headstage, or a W2100-Receiver. This makes cost-effective combinations with only one interface board and multiple recording systems possible. You can establish for example your experiments on 60, 120, or 256 electrodes with the MEA2100-System, then add the Multiwell-MEA-Headstage and start high-throughput screening. It's also possible to use the same interface board for in vitro MEA experiments and tethered / wireless in vivo recordings. This leaves you with even more flexibility in switching between possible configurations for your specific research needs.

Key features:

  • Real-time signal detection and feedback*
  • Freely programmable DSP*
  • Multiple inputs/outputs, including digital, analog, and audio
  • SuperSpeed USB 3.0 ports

* applicable for MEA2100(-Mini), ME2100, and W2100

Read more technical specifications