Innovations in Electrophysiology




Injection Goes Automatic

Numerous scientific fields such as biochemistry, molecular biology, electrophysiology, pharmacology or developmental biology take advantage of injecting cDNA, mRNA, proteins, and a variety of other compounds into living cells.
Oocytes of the African clawed toad Xenopus laevis are widely used as an expression system for ion channels, receptors, and transporters in drug development. The injection of fertilized eggs or embryos of the zebra fish Danio rerio is a common technique in developmental biology.

Until now, injection of nanoliter volumes into cells or embryos has been time-consuming and highly qualified personnel was required in order to get reasonable and reproducible results.
Multi Channel Systems is proud to present the Roboinject, the first and only commercially available fully automated robot for compound injection into oocytes, eggs, and embryos using industry standard 96, 384, as well as custom well plates.

The automation of cell injection not only saves time and money but also greatly enhances reproducibility of injection and survival of cells. It allows your highly qualified personnel to do away with routine work and to concentrate on science.

Furthermore, Xenopus oocytes processed in 96-well plates by the Roboinject can be further analyzed with the Roboocyte2, our fully automated system for high-throughput, two-electrode voltage-clamp based secondary screenings.