Innovations in Electrophysiology

Pancreatic Islet cells

Perrier R, Pirog A, Jaffredo M, Gaitan J, Catargi B, Renaud S, Raoux M, Lang J (2018) Bioelectronic organ-based sensor for microfluidic real-time analysis of the demand in insulin. Biosens Bioelectron 117:253-259.

Schönecker S, Boven KH, Kraushaar U (2018) Beta-Screen: Non-invasive and easy to use MEA-based parallelized screening system for intact islets of Langerhans. Diabetologie und Stoffwechsel 13:LB FV 8.

Koutsouras DA, Perrier R, Villarroel Marquez A, Pirog A, Pedraza E, Cloutet E, Renaud S, Raoux M, Malliaras GG, Lang J (2017) Simultaneous monitoring of single cell and of micro-organ activity by PEDOT:PSS covered multi-electrode arrays. Mater Sci Eng C Mater Biol Appl 81:84-89.

Maczewsky J, Sikimic J, Bauer C, Krippeit-Drews P, Wolke C, Lendeckel U, Barthlen W, Drews G (2017) The LXR Ligand T0901317 Acutely Inhibits Insulin Secretion by Affecting Mitochondrial Metabolism. Endocrinology 158:2145-2154.

Pirog A, Bornat Y, Renaud S, Perrier R, Jaffredo M, Raoux M, Lang J (2017) A versatile electrode sorting module for MEAs: Implementation in a FPGA-based real-time system. 2017 IEEE Biomedical Circuits and Systems Conference (BioCAS):1-4.

Lebreton F, Pirog A, Belouah I, Bosco D, Berney T, Meda P, Bornat Y, Catargi B, Renaud S, Raoux M, Lang J (2015) Slow potentials encode intercellular coupling and insulin demand in pancreatic beta cells. Diabetologia 58:1291-1299.

Pedraza E, Karajic A, Raoux M, Perrier R, Pirog A, Lebreton F, Arbault S, Gaitan J, Renaud S, Kuhn A, Lang J (2015) Guiding pancreatic beta cells to target electrodes in a whole-cell biosensor for diabetes. Lab Chip.

Schonecker S, Kraushaar U, Guenther E, Gerst F, Ullrich S, Haring HU, Konigsrainer A, Barthlen W, Drews G, Krippeit-Drews P (2015) Human Islets Exhibit Electrical Activity on Microelectrode Arrays (MEA). Exp Clin Endocrinol Diabetes.

Leberton F (2014) Electrical signals from pancreatic islets recorded on multielectrode arrays: characterization and application to the phenotyping of transgenic animals. . DOCTEUR DE L’UNIVERSITÉ DE BORDEAUX.

Renaud S, Catargi B, Lang J (2014) Biosensors in diabetes : how to get the most out of evolution and transpose it into a signal. IEEE Pulse 5:30-34.

Schonecker S, Kraushaar U, Dufer M, Sahr A, Hardtner C, Guenther E, Walther R, Lendeckel U, Barthlen W, Krippeit-Drews P, Drews G (2014) Long-term culture and functionality of pancreatic islets monitored using microelectrode arrays. Integr Biol (Camb).

Nguyen QV, Caro A, Raoux M, Quotb A, Floderer JB, Bornat Y, Renaud S, Lang J (2013) A novel bioelectronic glucose sensor to process distinct electrical activities of pancreatic beta-cells. Conf Proc IEEE Eng Med Biol Soc 2013:172-175.

Schönecker S, Kraushaar U, Guenther E, Düfer M, Sahr A, Härdtner C, Walther R, Lendeckel U, Barthlen W, Krippeit-Drews P, Drews G (2013) Microelectrode arrays as a new approach in beta-cell research: from mice to men In: EASD-Meeting. Barcelona.

Quotb A, Bornat Y, Raoux M, Lang J, Renaud S (2012) NeuroBetaMed: A re-configurable wavelet-based event detection circuit for in vitro biological signals. In: Circuits and Systems (ISCAS), 2012 IEEE International Symposium.

Pfeiffer T, Kraushaar U, Dufer M, Schonecker S, Haspel D, Gunther E, Drews G, Krippeit-Drews P (2011) Rapid functional evaluation of beta-cells by extracellular recording of membrane potential oscillations with microelectrode arrays. Pflugers Arch 462:835-840.

Raoux M, Bontorin G, Bornat Y, Lang J, Renaud S (2011) Bioelectronic Sensing of Insulin Demand. In: Biohybrid Systems: Nerves, Interfaces, and Machines (Jung R, ed): Wiley-VCH Verlag GmbH & Co. KGaA.

Raoux M, Bornat Y, Quotb A, Catargi B, Renaud S, Lang J (2011) Non-invasive long-term and real-time analysis of endocrine cells on micro-electrode arrays. J Physiol.

Bornat Y, Raoux M, Boutaib Y, Morin FO, Charpentier G, Lang J, Renaud S (2010) Detection of electrical activity of pancreatic ß-cells using micro-electrode arrays. Proceedings 5th IEEE Int. Symposium on Electronic Design, Test & Applications.