Innovations in Electrophysiology

Pharmacology (other)

Barbero-Castillo A, Riefolo F, Matera C, Caldas-Martínez S, Mateos-Aparicio P, Weinert JF, Garrido-Charles A, Claro E, Sanchez-Vives MV, Gorostiza P (2021) Control of Brain State Transitions with a Photoswitchable Muscarinic Agonist. Adv Sci (Weinh):e2005027.

Cogo A, Mangin G, Maïer B, Callebert J, Mazighi M, Chabriat H, Launay JM, Huberfeld G, Kubis N (2021) Increased serum QUIN/KYNA is a reliable biomarker of post-stroke cognitive decline. Mol Neurodegener 16:7.

Dalbøge LS, Jacobsen JM, Mehrotra S, Mercer AJ, Cox N, Liu F, Bennett CM, Said M, Tang-Christensen M, Raun K, Hansen JL, Grove KL, Baquero AF (2021) Evaluation of VGF peptides as potential anti-obesity candidates in pre-clinical animal models. Peptides 136:170444.

Izsak J, Seth H, Iljin M, Theiss S, Ågren H, Funa K, Aigner L, Hanse E, Illes S (2021) Differential acute impact of therapeutically effective and overdose concentrations of lithium on human neuronal single cell and network function. Transl Psychiatry 11:281.

Lü X-Y, Hou K, Zhao Y-F, An S, Wang Z-G (2021) Conjoint analysis of influence of LC-HCL and Mor-HCL on Vth and neurite length in hippocampal neuronal network. Neuroscience Letters 751:135801.

Milligan CJ, Pachernegg S (2021) Utilising Automated Electrophysiological Platforms in Epilepsy Research. In: Patch Clamp Electrophysiology: Methods and Protocols (Dallas M, Bell D, eds), pp 133-155. New York, NY: Springer US.

Nikolaeva-Koleva M, Butron L, González-Rodríguez S, Devesa I, Valente P, Serafini M, Genazzani AA, Pirali T, Ballester GF, Fernández-Carvajal A, Ferrer-Montiel A (2021) A capsaicinoid-based soft drug, AG1529, for attenuating TRPV1-mediated histaminergic and inflammatory sensory neuron excitability. Sci Rep 11:246.

Parrini M, Naskar S, Alberti M, Colombi I, Morelli G, Rocchi A, Nanni M, Piccardi F, Charles S, Ronzitti G, Mingozzi F, Contestabile A, Cancedda L (2021) Restoring neuronal chloride homeostasis with anti-NKCC1 gene therapy rescues cognitive deficits in a mouse model of Down syndrome. Mol Ther.

Solomon EA, Rooney AM, Rodriguez AM, Micheva-Viteva SN, Bashir R, Iyer R, Harris JF (2021) Neuromuscular Junction Model optimized for electrical platforms. Tissue Engineering Part C: Methods 0:null.

Tauskela JS, Kuebler ES, Thivierge J-P, Aylsworth A, Hewitt M, Zhao X, Mielke JG, Martina M (2021) Resilience of network activity in preconditioned neurons exposed to ‘stroke-in-a-dish’ insults. Neurochemistry International 146:105035.

Alloisio S, Clericuzio M, Nobile M, Salis A, Damonte G, Canali C, Fortuna-Perez AP, Cornara L, Burlando B (2020) Cannabis-like activity of Zornia latifolia Sm. detected in vitro on rat cortical neurons: major role of the flavone syzalterin. Drug Chem Toxicol:1-13.

Armada-Moreira A, Coelho JE, Lopes LV, Sebastião AM, Städler B, Vaz SH (2020) Multicompartment Microreactors Prevent Excitotoxic Dysfunctions In Rat Primary Cortical Neurons. Adv Biosyst:e2000139.

Aupy J, Ribot B, Dovero S, Biendon N, Nguyen TH, Porras G, Deffains M, Guehl D, Burbaud P (2020) Acute Striato-Cortical Synchronization Induces Focal Motor Seizures in Primates. Cereb Cortex 30:6469-6480.

Badman RP, Moore SL, Killian JL, Feng T, Cleland TA, Hu F, Wang MD (2020) Dextran-coated iron oxide nanoparticle-induced nanotoxicity in neuron cultures. Sci Rep 10:11239.

Bódi V, Csikós V, Rátkai EA, Szűcs A, Tóth A, Szádeczky-Kardoss K, Dobolyi Á, Schlett K, Világi I, Varró P (2020) Short-term neuronal effects of fumonisin B1 on neuronal activity in rodents. Neurotoxicology 80:41-51.

Cornara L, Ambu G, Trombetta D, Denaro M, Alloisio S, Frigerio J, Labra M, Ghimire G, Valussi M, Smeriglio A (2020) Comparative and Functional Screening of Three Species Traditionally used as Antidepressants: Valeriana officinalis L., Valeriana jatamansi Jones ex Roxb. and Nardostachys jatamansi (D.Don) DC. Plants (Basel) 9.

Deffains M, Hai Nguyen T, Orignac H, Biendon N, Dovero S, Bezard E, Boraud T (2020) In vivo electrophysiological validation of DREADD-based modulation of pallidal neurons in the non-human primate. Eur J Neurosci.

Deffains M, Haï Nguyen T, Orignac H, Biendon N, Dovero S, Bezard E, Boraud T (2020) In vivo electrophysiological validation of DREADD-based inhibition of pallidal neurons in the non-human primate. bioRxiv:2020.2001.2003.893610.

Di Consiglio E, Pistollato F, Mendoza-De Gyves E, Bal-Price A, Testai E (2020) Integrating biokinetics and in vitro studies to evaluate developmental neurotoxicity induced by chlorpyrifos in human iPSC-derived neural stem cells undergoing differentiation towards neuronal and glial cells. Reprod Toxicol.

Fischer S, Schlotthauer I, Kizner V, Macartney T, Dorner-Ciossek C, Gillardon F (2020) Loss-of-function Mutations of CUL3, a High Confidence Gene for Psychiatric Disorders, Lead to Aberrant Neurodevelopment In Human Induced Pluripotent Stem Cells. Neuroscience.

Frontera JL, Baba Aissa H, Sala RW, Mailhes-Hamon C, Georgescu IA, Léna C, Popa D (2020) Bidirectional control of fear memories by cerebellar neurons projecting to the ventrolateral periaqueductal grey. Nat Commun 11:5207.

Hakim-Eshed V, Boulos A, Cohen-Rosenzweig C, Yu-Taeger L, Ziv T, Kwon YT, Riess O, Phuc Nguyen HH, Ziv NE, Ciechanover A (2020) Site-specific ubiquitination of pathogenic huntingtin attenuates its deleterious effects. Proc Natl Acad Sci U S A.

Hwang ES, Kim HB, Lee S, Kim MJ, Kim KJ, Han G, Han SY, Lee EA, Yoon JH, Kim DO, Maeng S, Park JH (2020) Antidepressant-like effects of beta-caryophyllene on restraint plus stress-induced depression. Behav Brain Res 380:112439.

Kharouf Q, Phillips AM, Bleakley LE, Morrisroe E, Oyrer J, Jia L, Ludwig A, Jin L, Nicolazzo JA, Cerbai E, Romanelli MN, Petrou S, Reid CA (2020) The hyperpolarization-activated cyclic nucleotide-gated 4 channel as a potential anti-seizure drug target. Br J Pharmacol.

Kovacs A, Vermeer DW, Madeo M, Reavis HD, Vermeer SJ, Williamson CS, Rickel A, Stamp J, Lucido CT, Cain J, Bell M, Morgan MM, Yoon J-Y, Mitchell MA, Tulina N, Stuckelberger S, Budina A, Omran DK, Jung E, Schwartz LE, Eichwald T, Hong Z, Weimer J, Hooper JE, Godwin AK, Talbot S, Drapkin R, Vermeer PD (2020) Tumor-infiltrating nerves create an electro-physiologically active microenvironment and contribute to treatment resistance. bioRxiv:2020.2004.2024.058594.

Kumari J, Bendre AD, Bhosale S, Vinnakota R, Burada AP, Ravelli R, Peters PJ, Joshi M, Kumar J (2020) Structural dynamics of the GluK3-kainate receptor neurotransmitter binding domains revealed by cryo-EM. Int J Biol Macromol.

Latchoumane C-FV, Betancur MI, Simchick G, Sun MK, Forghani R, Lenear CE, Ahmed A, Mohankumar R, Balaji N, Mason HD, Holmes PV, Zhao Q, Bellamkonda RV, Karumbaiah L (2020) Neurotrophic Factor-Laden Acellular Chondroitin Sulfate Scaffolds Promote Chronic Functional Recovery After Severe Traumatic Brain Injury. bioRxiv:2020.2006.2021.116970.

Lezmy J, Gelman H, Katsenelson M, Styr B, Tikochinsky E, Lipinsky M, Peretz A, Slutsky I, Attali B (2020) M-current inhibition in hippocampal excitatory neurons triggers intrinsic and synaptic homeostatic responses at different temporal scales. J Neurosci.

Liu JYH, Du P, Rudd JA (2020) Acetylcholine Exerts Inhibitory and Excitatory Actions on Mouse Ileal Pacemaker Activity: The Role of Muscarinic versus Nicotinic Receptors. Am J Physiol Gastrointest Liver Physiol.

Liu Y, Bian H, Xu S, Shu S, Jia J, Chen J, Cao X, Bao X, Gu Y, Xia S, Yang H, Yu L, Xu Y, Zhu X (2020) Muscone Ameliorates Synaptic Dysfunction and Cognitive Deficits in APP/PS1 Mice. J Alzheimers Dis.

Manduca JD, Thériault RK, Williams OOF, Rasmussen DJ, Perreault ML (2020) Transient dose-dependent effects of ketamine on neural oscillatory activity in Wistar-Kyoto rats. Neuroscience.

Mossink B, van Rhijn J-R, Wang S, van Hugte EJH, Linda K, Bak J, Verboven AHA, Selten M, Anania A, Jansen S, Keller JM, Gunnewiek TK, Schoenmaker C, Oudakker A, Frega M, van Bokhoven H, Schubert D, Kasri NN (2020) Cadherin-13 is a critical regulator of GABAergic modulation in human stem cell derived neuronal networks. bioRxiv:2020.2005.2007.082453.

Muzio L, Sirtori R, Gornati D, Eleuteri S, Fossaghi A, Brancaccio D, Manzoni L, Ottoboni L, Feo L, Quattrini A, Mastrangelo E, Sorrentino L, Scalone E, Comi G, Marinelli L, Riva N, Milani M, Seneci P, Martino G (2020) Retromer stabilization results in neuroprotection in a model of Amyotrophic Lateral Sclerosis. Nat Commun 11:3848.

Neto E, Leitão L, Mateus J, Sousa DM, Conceição F, Alves CJ, Oreffo ROC, West J, Aguiar P, Lamghari M (2020) Sensory neurons sprouting is dependent on osteoclast-derived extracellular vesicles involving the activation of epidermal growth factor receptors. bioRxiv:259218.

Nicol AU, Morton AJ (2020) Characteristic patterns of EEG oscillations in sheep (Ovis aries) induced by ketamine may explain the psychotropic effects seen in humans. Sci Rep 10:9440.

Nomura K, Narimatsu E, Inoue H, Kyan R, Sawamoto K, Uemura S, Kakizaki R, Harada K (2020) Mechanism of central hypopnoea induced by organic phosphorus poisoning. Sci Rep 10:15834.

Patel RR, Ping X, Patel SR, McDermott JS, Krajewski JL, Chi XX, Nisenbaum ES, Jin X, Cummins TR (2020) Preferential Pharmacological Inhibition of Nav1.6, but not Nav1.1, Abolishes Epileptiform Activity Induced by 4-AP in Mouse Cortical Slices. bioRxiv:2020.2005.2029.124693.

Pemberton DK (2020) The Effects of the G Protein-Coupled Estrogen Receptor on Early Neuronal Development in Hippocampal and Cortical Neurons.

Poston RG, Murphy L, Rejepova A, Ghaninejad-Esfahani M, Segales J, Mulligan K, Saha RN (2020) Certain ortho-hydroxylated brominated ethers are promiscuous kinase inhibitors that impair neuronal signaling and neurodevelopmental processes. J Biol Chem 295:6120-6137.

Reasmussen D (2020) Effect of Ketamine Treatment on Neuronal Oscillatory Activity in the Nucleus Accumbens and Hippocampus in an Animal Model of Treatment-Resistant Depression.

Renner H, Grabos M, Becker KJ, Kagermeier TE, Wu J, Otto M, Peischard S, Zeuschner D, TsyTsyura Y, Disse P, Klingauf J, Leidel SA, Seebohm G, Schöler HR, Bruder JM (2020) A fully automated high-throughput workflow for 3D-based chemical screening in human midbrain organoids. Elife 9.

Sambri I, Massa F, Gullo F, Meneghini S, Cassina L, Carraro M, Dina G, Quattrini A, Patanella L, Carissimo A, Iuliano A, Santorelli F, Codazzi F, Grohovaz F, Bernardi P, Becchetti A, Casari G (2020) Impaired flickering of the permeability transition pore causes SPG7 spastic paraplegia. EBioMedicine 61:103050.

Smeriglio A, Trombetta D, Alloisio S, Cornara L, Denaro M, Garbati P, Grassi G, Circosta C (2020) Promising in vitro antioxidant, anti-acetylcholinesterase and neuroactive effects of essential oil from two non-psychotropic Cannabis sativa L. biotypes. Phytother Res.

Sowmithra S, Jain NK, Bhonde R, Datta I (2020) Recovery of Human Embryonic Stem Cells-Derived Neural Progenitors Exposed to Hypoxic-Ischemic-Reperfusion Injury by Indirect Exposure to Wharton's Jelly Mesenchymal Stem Cells Through Phosphatidyl-inositol-3-Kinase Pathway. Cell Mol Neurobiol.

Sun Y, Sommerville NR, Liu JYH, Ngan MP, Poon D, Ponomarev ED, Lu Z, Kung JSC, Rudd JA (2020) Intra-gastrointestinal amyloid-β1-42 oligomers perturb enteric function and induce Alzheimer's disease pathology. J Physiol.

Theriault RK, Manduca JD, Blight CR, Khokhar JY, Akhtar TA, Perreault ML (2020) Acute mitragynine administration suppresses cortical oscillatory power and systems theta coherence in rats. J Psychopharmacol:269881120914223.

Vakili S, Ahooyi TM, Yarandi SS, Donadoni M, Rappaport J, Sariyer IK (2020) Molecular and Cellular Impact of Inflammatory Extracellular Vesicles (EVs) Derived from M1 and M2 Macrophages on Neural Action Potentials. Brain Sci 10.

Vicente-Baz J, Rivera-Arconada I (2020) Spinal Actions of the NSAID Diclofenac on Nociceptive Transmission in Comparison to the K(v)7 Channel Opener Flupirtine. Neuroscience 440:186-195.

Worley NB, Varela JA, Gaillardetz GP, Hill MN, Christianson JP (2020) Monoacylglycerol lipase alpha inhibition alters prefrontal cortex excitability and blunts the consequences of traumatic stress in rat. Neuropharmacology 166:107964.

Amano Y, Honda H, Nukada Y, Ikeda N, Yamane M, Nakano K, Kameyama A, Morita O (2019) Safety Pharmacological Evaluation of the Coffee Component, Caffeoylquinic Acid, and Its Metabolites, Using Ex Vivo and In Vitro Profiling Assays. Pharmaceuticals (Basel) 12.

Bonaventura J, Eldridge MAG, Hu F, Gomez JL, Sanchez-Soto M, Abramyan AM, Lam S, Boehm MA, Ruiz C, Farrell MR, Moreno A, Galal Faress IM, Andersen N, Lin JY, Moaddel R, Morris PJ, Shi L, Sibley DR, Mahler SV, Nabavi S, Pomper MG, Bonci A, Horti AG, Richmond BJ, Michaelides M (2019) High-potency ligands for DREADD imaging and activation in rodents and monkeys. Nat Commun 10:4627.

Choukairi Z, Hazzaz T, Lkhider M, Ferrandez JM, Fechtali T (2019) Effect of salvia Officinalis L. and Rosmarinus Officinalis L. leaves extracts on anxiety and neural activity. Bioinformation 16.

Domise M, Sauve F, Didier S, Caillerez R, Begard S, Carrier S, Colin M, Marinangeli C, Buee L, Vingtdeux V (2019) Neuronal AMP-activated protein kinase hyper-activation induces synaptic loss by an autophagy-mediated process. Cell Death Dis 10:221.

Donadoni M, Cicalese S, Sarkar DK, Chang SL, Sariyer IK (2019) Alcohol exposure alters pre-mRNA splicing of antiapoptotic Mcl-1L isoform and induces apoptosis in neural progenitors and immature neurons. Cell Death Dis 10:447.

Foliaki ST, Lewis V, Islam AMT, Ellett LJ, Senesi M, Finkelstein DI, Roberts B, Lawson VA, Adlard PA, Collins SJ (2019) Early existence and biochemical evolution characterise acutely synaptotoxic PrPSc. PLoS Pathog 15:e1007712.

Foute Nelong MT, Manduca JD, Zonneveld PM, Perreault ML (2019) Asenapine Maleate normalizes low frequency oscillatory deficits in a neurodevelopmental model of schizophrenia. Neurosci Lett:134404.

Gao F, Gao K, He C, Liu M, Wan H, Wang P (2019) Multi-site dynamic recording for Aβ oligomers-induced Alzheimer's disease in vitro based on neuronal network chip. Biosensors and Bioelectronics.

Gonzalez-Gil I, Zian D, Vazquez-Villa H, Hernandez-Torres G, Martinez RF, Khiar-Fernandez N, Rivera R, Kihara Y, Devesa I, Mathivanan S, Del Valle CR, Zambrana-Infantes E, Puigdomenech M, Cincilla G, Sanchez-Martinez M, Rodriguez de Fonseca F, Ferrer-Montiel AV, Chun J, Lopez-Vales R, Lopez-Rodriguez ML, Ortega-Gutierrez S (2019) A Novel Agonist of the Type 1 Lysophosphatidic Acid Receptor (LPA1), UCM-05194, Shows Efficacy in Neuropathic Pain Amelioration. J Med Chem.

Gortz P, Henning U, Theiss S, Lange-Asschenfeldt C (2019) Effect fingerprints of antipsychotic drugs on neural networks in vitro. J Neural Transm (Vienna).

Kizner V, Fischer S, Naujock M (2019) Multielectrode Array (MEA)-Based Detection of Spontaneous Network Activity in Human iPSC-Derived Cortical Neurons. Methods Mol Biol 1994:209-216.

Koch H, Niturad CE, Theiss S, Bien CG, Elger C, Wandinger KP, Vincent A, Malter M, Kortvelyessy P, Lerche H, Dihne M (2019) In vitro neuronal network activity as a new functional diagnostic system to detect effects of Cerebrospinal fluid from autoimmune encephalitis patients. Sci Rep 9:5591.

Maestrelli F, Landucci E, De Luca E, Nerli G, Bergonzi MC, Piazzini V, Pellegrini-Giampietro DE, Gullo F, Becchetti A, Tadini-Buoninsegni F, Francesconi O, Nativi C (2019) Niosomal Formulation of a Lipoyl-Carnosine Derivative Targeting TRPA1 Channels in Brain. Pharmaceutics 11.

Mendis GDC, Berecki G, Morrisroe E, Pachernegg S, Li M, Varney M, Osborne PB, Reid CA, Halgamuge S, Petrou S (2019) Discovering the pharmacodynamics of conolidine and cannabidiol using a cultured neuronal network based workflow. Sci Rep 9:121.

Miller SJ, Philips T, Kim N, Dastgheyb R, Chen Z, Hsieh YC, Daigle JG, Datta M, Chew J, Vidensky S, Pham JT, Hughes EG, Robinson MB, Sattler R, Tomer R, Suk JS, Bergles DE, Haughey N, Pletnikov M, Hanes J, Rothstein JD (2019) Molecularly defined cortical astroglia subpopulation modulates neurons via secretion of Norrin. Nat Neurosci 22:741-752.

Mohseni Ahooyi T, Torkzaban B, Shekarabi M, Tahrir FG, Decoppet EA, Cotto B, Langford D, Amini S, Khalili K (2019) Perturbation of synapsins homeostasis through HIV-1 Tat-mediated suppression of BAG3 in primary neuronal cells. Cell Death Dis 10:473.

Okamoto SI, Prikhodko O, Pina-Crespo J, Adame A, McKercher SR, Brill LM, Nakanishi N, Oh CK, Nakamura T, Masliah E, Lipton SA (2019) NitroSynapsin for the treatment of neurological manifestations of tuberous sclerosis complex in a rodent model. Neurobiol Dis 127:390-397.

Papariello A, Newell-Litwa K (2019) Human-Derived Brain Models: Windows Into Neuropsychiatric Disorders and Drug Therapies. Assay Drug Dev Technol.

Patel AM, Wierda K, Thorrez L, van Putten M, De Smedt J, Ribeiro L, Tricot T, Gajjar M, Duelen R, Van Damme P, De Waele L, Goemans N, Tanganyika-de Winter C, Costamagna D, Aartsma-Rus A, van Duyvenvoorde H, Sampaolesi M, Buyse GM, Verfaillie CM (2019) Dystrophin deficiency leads to dysfunctional glutamate clearance in iPSC derived astrocytes. Transl Psychiatry 9:200.

Shafer TJ (2019) Application of Microelectrode Array Approaches to Neurotoxicity Testing and Screening. Adv Neurobiol 22:275-297.

Shirokova OM, Sokolov RA, Korotchenko SA, Pershin VI, Ermin KV, Glyavina MM, Zhuchenko M, Andreeva NN, Shchelchkova NA, Mukhina IV (2019) Neurotropic Effect of Carbamylated Darbepoietin on the Model of Primary Hippocampal Culture. Sovremennye tehnologii v medicine 11:87.

Sohn PD, Huang CT, Yan R, Fan L, Tracy TE, Camargo CM, Montgomery KM, Arhar T, Mok SA, Freilich R, Baik J, He M, Gong S, Roberson ED, Karch CM, Gestwicki JE, Xu K, Kosik KS, Gan L (2019) Pathogenic Tau Impairs Axon Initial Segment Plasticity and Excitability Homeostasis. Neuron.

Steidl E, Gleyzes M, Maddalena F, Debanne D, Buisson B (2019) Neuroservice proconvulsive (NS-PC) set: A new platform of electrophysiology-based assays to determine the proconvulsive potential of lead compounds. J Pharmacol Toxicol Methods:106587.

Van De Vijver S, Missault S, Van Soom J, Van Der Veken P, Augustyns K, Joossens J, Dedeurwaerdere S, Giugliano M (2019) The effect of pharmacological inhibition of Serine Proteases on neuronal networks in vitro. PeerJ 7:e6796.

Bar El Y, Kanner S, Barzilai A, Hanein Y (2018) Activity changes in neuron-astrocyte networks in culture under the effect of norepinephrine. PLoS ONE 13:e0203761.

Bar El Y, Kanner S, Barzilai A, Hanein Y (2018) Calcium imaging, MEA recordings and Immunostaining images dataset of Neuron-Astrocyte Networks in Culture under the Effect of Norepinephrine. Gigascience.

Blauwblomme T, Dossi E, Pellegrino C, Goubert E, Gal Iglesias B, Sainte-Rose C, Rouach N, Nabbout R, Huberfeld G (2018) GABAergic transmission underlies interictal epileptogenicity in pediatric FCD. Ann Neurol.

Caputo L (2018) Chemical and Biological study of natural substances active on the Central Nervous System. Dipartimento di Farmacia.

Chang YY, Gong XW, Gong HQ, Liang PJ, Zhang PM, Lu QC (2018) GABAA Receptor Activity Suppresses the Transition from Inter-ictal to Ictal Epileptiform Discharges in Juvenile Mouse Hippocampus. Neurosci Bull.

Chaudhuri AD, Dastgheyb RM, Yoo SW, Trout A, Talbot CC, Jr., Hao H, Witwer KW, Haughey NJ (2018) TNFalpha and IL-1beta modify the miRNA cargo of astrocyte shed extracellular vesicles to regulate neurotrophic signaling in neurons. Cell Death Dis 9:363.

Chong SA, Balosso S, Vandenplas C, Szczesny G, Hanon E, Claes K, Van Damme X, Danis B, Van Eyll J, Wolff C, Vezzani A, Kaminski RM, Niespodziany I (2018) Intrinsic Inflammation Is a Potential Anti-Epileptogenic Target in the Organotypic Hippocampal Slice Model. Neurotherapeutics.

Couly S, Paucard A, Bonneaud N, Maurice T, Benigno L, Jourdan C, Cohen-Solal C, Vignes M, Maschat F (2018) Improvement of BDNF signalling by P42 peptide in Huntington's disease. Hum Mol Genet.

Distasi C, Ruffinatti FA, Dionisi M, Antoniotti S, Gilardino A, Croci G, Riva B, Bassino E, Alberto G, Castroflorio E, Incarnato D, Morandi E, Martra G, Oliviero S, Munaron L, Lovisolo D (2018) SiO2 nanoparticles modulate the electrical activity of neuroendocrine cells without exerting genomic effects. Sci Rep 8:2760.

Gaburro J, Bhatti A, Sundaramoorthy V, Dearnley M, Green D, Nahavandi S, Paradkar PN, Duchemin JB (2018) Zika virus-induced hyper excitation precedes death of mouse primary neuron. Virol J 15:79.

Georgopoulos AP, Tsilibary EC, Souto EP, James LM, Engdahl BE, Georgopoulos A (2018) Adverse effects of Gulf War Illness (GWI) serum on neural cultures and their prevention by healthy serum. Journal of Neurology & Neuromedicine 3:19-27.

Hadwen J, Schock S, Mears A, Yang R, Charron P, Zhang L, Xi HS, MacKenzie A (2018) Transcriptomic RNAseq drug screen in cerebrocortical cultures: toward novel neurogenetic disease therapies. Hum Mol Genet 27:3206-3217.

Hagman S, Makinen A, Yla-Outinen L, Huhtala H, Elovaara I, Narkilahti S (2018) Effects of inflammatory cytokines IFN-gamma, TNF-alpha and IL-6 on the viability and functionality of human pluripotent stem cell-derived neural cells. J Neuroimmunol.

Hassink GC, Raiss CC, Segers-Nolten IMJ, van Wezel RJA, Subramaniam V, le Feber J, Claessens M (2018) Exogenous alpha-synuclein hinders synaptic communication in cultured cortical primary rat neurons. PLoS ONE 13:e0193763.

Kapkaeva MR, Genrikhs EE, Stelmashook EV, Kondratenko RV, Isaev NK, Khaspekov LG (2018) Neuronal Networks on Multielectrode Arrays as High Sensitive Biosensors of the Functional State of Nerve Cells. Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology 12.

Kopanitsa MV, Gou G, Afinowi NO, Bayes A, Grant SGN, Komiyama NH (2018) Chronic treatment with a MEK inhibitor reverses enhanced excitatory field potentials in Syngap1(+/-) mice. Pharmacol Rep 70:777-783.

Lee S, Kim HB, Hwang ES, Kim ES, Kim SS, Jeon TD, Song MC, Lee JS, Chung MC, Maeng S, Park JH (2018) Antidepressant-like Effects of p-Coumaric Acid on LPS-induced Depressive and Inflammatory Changes in Rats. Exp Neurobiol 27:189-199.


Mata A, Gil V, Perez-Clausell J, Dasilva M, Gonzalez-Calixto MC, Soriano E, Garcia-Verdugo JM, Sanchez-Vives MV, Del Rio JA (2018) New functions of Semaphorin 3E and its receptor PlexinD1 during developing and adult hippocampal formation. Sci Rep 8:1381.

Myers TL, Gonzalez OC, Stein JB, Bazhenov M (2018) Characterizing concentration-dependent neural dynamics of 4-aminopyridine-induced epileptiform activity. bioRxiv:252726.

Perez-Gomez A, Cabrera-Garcia D, Warm D, Marini AM, Salas Puig J, Fernandez-Sanchez MT, Novelli A (2018) Selective Enhancement of Domoic Acid Toxicity in Primary Cultures of Cerebellar Granule Cells by Lowering Extracellular Na+ Concentration. Toxicol Sci 161:103-114.

Perez-Gomez A, Cabrera-Garcia D, Warm D, Marini AM, Salas Puig J, Fernandez-Sanchez MT, Novelli A (2018) From the Cover: Selective Enhancement of Domoic Acid Toxicity in Primary Cultures of Cerebellar Granule Cells by Lowering Extracellular Na+ Concentration. Toxicol Sci 161:103-114.

Serafini M, Griglio A, Aprile S, Seiti F, Travelli C, Pattarino F, Grosa G, Sorba G, Genazzani AA, Gonzalez-Rodriguez S, Butron L, Devesa I, Fernandez-Carvajal A, Pirali T, Ferrer-Montiel A (2018) Targeting Transient Receptor Potential Vanilloid 1 (TRPV1) Channel Softly: The Discovery of Passerini Adducts as a Topical Treatment for Inflammatory Skin Disorders. J Med Chem 61:4436-4455.

Srivastava PK, van Eyll J, Godard P, Mazzuferi M, Delahaye-Duriez A, Steenwinckel JV, Gressens P, Danis B, Vandenplas C, Foerch P, Leclercq K, Mairet-Coello G, Cardenas A, Vanclef F, Laaniste L, Niespodziany I, Keaney J, Gasser J, Gillet G, Shkura K, Chong SA, Behmoaras J, Kadiu I, Petretto E, Kaminski RM, Johnson MR (2018) A systems-level framework for drug discovery identifies Csf1R as an anti-epileptic drug target. Nat Commun 9:3561.

Sumitha R, Manjunatha VM, Sabitha RK, Alladi PA, Nalini A, Rao LT, Chandrasekhar Sagar BK, Steinbusch HWM, Kramer BW, Sathyaprabha TN, Raju TR (2018) Cerebrospinal Fluid from Patients with Sporadic Amyotrophic Lateral Sclerosis Induces Degeneration of Motor Neurons Derived from Human Embryonic Stem Cells. Mol Neurobiol.

Swiatkowski P, Sewell E, Sweet ES, Dickson S, Swanson RA, McEwan SA, Cuccolo N, McDonnell ME, Patel MV, Varghese N, Morrison B, Reitz AB, Meaney DF, Firestein BL (2018) Cypin: A novel target for traumatic brain injury. Neurobiol Dis 119:13-25.

Teppola H, Okujeni S, Linne M-L, Egert U (2018) AMPA, NMDA and GABAA receptor mediated network burst dynamics in cortical cultures in vitro. arXiv.

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