Innovations in Electrophysiology

Synaptic plasticity & learning

Banerjee PS, Goshal S, Giardet C, DeMars KM, Yang C, Niehoff ML, Nguyen AD, Jayanth P, Mersman BA, Xu F, Banks WA, Hansen KM, Zhang J, Candelario-Jalil E, Farr SA, Butler AA (2021) Adropin expression correlates with age-related neuropathologies in the human brain and improves neuroin ammation and cognitive function in aging mice. Research Square.

Darch HT, Collins MK, O'Riordan KJ, Cryan JF (2021) Microbial memories: Sex-dependent impact of the gut microbiome on hippocampal plasticity. Eur J Neurosci.

Largo-Barrientos P, Apóstolo N, Creemers E, Callaerts-Vegh Z, Swerts J, Davies C, McInnes J, Wierda K, De Strooper B, Spires-Jones T, de Wit J, Uytterhoeven V, Verstreken P (2021) Lowering Synaptogyrin-3 expression rescues Tau-induced memory defects and synaptic loss in the presence of microglial activation. Neuron.

Park H-S, Hwang E-S, Choi G-Y, Kim H-B, Park K-S, Sul J-Y, Hwang Y, Choi GW, Kim BI, Park HJ, Maeng S, Park J-H (2021) Sulforaphane enhances long-term potentiation and ameliorate scopolamine-induced memory impairment. Physiology & Behavior 238:113467.

Pazienti A, Galluzzi A, Dasilva M, Sanchez-Vives MV, Mattia M (2021) Slow waves form expanding, memory-rich mesostates steered by local excitability in fading anesthesia. bioRxiv:2021.2001.2021.427671.

Zheng Y, Tian C, Dong L, Tian L, Glabonjat RA, Xiong C (2021) Effect of arsenic-containing hydrocarbon on the long-term potentiation at Schaffer Collateral-CA1 synapses from infantile male rat. Neurotoxicology 84:198-207.

Dong L, Li G, Gao Y, Lin L, Zheng Y, Cao XB (2020) Exploring the form- and time-dependent effect of low frequency electromagnetic fields on maintenance of hippocampal long-term potentiation. Eur J Neurosci.

Fernández-García S, Conde-Berriozabal S, García-García E, Gort-Paniello C, Bernal-Casas D, Barriga GG-D, López-Gil J, Muñoz-Moreno E, Sòria G, Campa L, Artigas F, Rodriguez MJ, Alberch J, Masana M (2020) M2 Cortex-Dorsolateral striatum stimulation reverses motor symptoms and synaptic deficits in Huntington’s Disease. bioRxiv:2020.2004.2008.032359.

Grosser S, Buck N, Braunewell K-H, Gilling KE, Wozny C, Fidzinski P, Behr J (2020) Loss of Long-Term Potentiation at Hippocampal Output Synapses in Experimental Temporal Lobe Epilepsy. Frontiers in Molecular Neuroscience 13.

Lensu S, Waselius T, Mäkinen E, Kettunen H, Virtanen A, Tiirola M, Penttonen M, Pekkala S, Nokia MS (2020) Irradiation of the head reduces adult hippocampal neurogenesis and impairs spatial memory, but leaves overall health intact in rats. Eur J Neurosci.

Lopez-Madrona VJ, Pérez-Montoyo E, Álvarez-Salvado E, Moratal D, Herreras O, Pereda E, Mirasso CR, Canals S (2020) Different theta frameworks coexist in the hippocampus and are coordinated during memory-guided exploration and novelty detection. bioRxiv:418434.

Urbano-Gámez JD, Benito I, Casañas JJ, Montesinos ML (2020) Prenatal treatment with rapamycin restores enhanced hippocampal mGluR-LTD and mushroom spine size in a Down’s syndrome mouse model. bioRxiv:2020.2004.2008.032029.

Zhang X, Yeh FC, Ju H, Jiang Y, Quan GFW, VanDongen AMJ (2020) Familiarity detection and memory consolidation in cortical assemblies. eNeuro.

Ayton S, Lei P, Appukuttan AT, Renoir T, Foliaki S, Chen F, Adlard PA, Hannan AJ, Bush AI (2019) Brain Zinc Deficiency Exacerbates Cognitive Decline in the R6/1 Model of Huntington's Disease. Neurotherapeutics.

Berret E, Kintscher M, Palchaudhuri S, Tang W, Osypenko D, Kochubey O, Schneggenburger R (2019) Insular cortex processes aversive somatosensory information and is crucial for threat learning. Science 364.

Feldmann LK, Le Prieult F, Felzen V, Thal SC, Engelhard K, Behl C, Mittmann T (2019) Proteasome and Autophagy-Mediated Impairment of Late Long-Term Potentiation (l-LTP) after Traumatic Brain Injury in the Somatosensory Cortex of Mice. Int J Mol Sci 20.

Rogers J, Chen F, Stanic D, Farzana F, Li S, Zeleznikow-Johnston AM, Nithianantharajah J, Churilov L, Adlard PA, Lanfumey L, Hannan AJ, Renoir T (2019) Paradoxical effects of exercise on hippocampal plasticity and cognition in mice with a heterozygous null mutation in the serotonin transporter gene. Br J Pharmacol.

Sohn PD, Huang CT, Yan R, Fan L, Tracy TE, Camargo CM, Montgomery KM, Arhar T, Mok SA, Freilich R, Baik J, He M, Gong S, Roberson ED, Karch CM, Gestwicki JE, Xu K, Kosik KS, Gan L (2019) Pathogenic Tau Impairs Axon Initial Segment Plasticity and Excitability Homeostasis. Neuron.

Tang W, Kochubey O, Kintscher M, Schneggenburger R (2019) Dopamine in the basal amygdala signals salient somatosensory events during fear learning. bioRxiv:716589.

Wang Y, Liu Q, Xie J, Feng R, Ma F, Wang F, Shen S, Wen T (2019) Dcf1 Affects Memory and Anxiety by Regulating NMDA and AMPA Receptors. Neurochem Res.

Wülfing JM, Kumar SS, Boedecker J, Riedmiller M, Egert U (2019) Adaptive long-term control of biological neural networks with Deep Reinforcement Learning. Neurocomputing.



Bovet-Carmona M, Menigoz A, Pinto S, Tambuyzer T, Krautwald K, Voets T, Aerts JM, Angenstein F, Vennekens R, Balschun D (2018) Disentangling the role of TRPM4 in hippocampus-dependent plasticity and learning: an electrophysiological, behavioral and FMRI approach. Brain Struct Funct 223:3557-3576.

Cavalier M, Ben Sedrine A, Thevenet L, Crouzin N, Guiramand J, de Jesus Ferreira MC, Cohen-Solal C, Barbanel G, Vignes M (2018) Disturbance of Metabotropic Glutamate Receptor-Mediated Long-Term Depression (mGlu-LTD) of Excitatory Synaptic Transmission in the Rat Hippocampus After Prenatal Immune Challenge. Neurochem Res.

Foliaki ST, Lewis V, Finkelstein DI, Lawson V, Coleman HA, Senesi M, Islam AMT, Chen F, Sarros S, Roberts B, Adlard PA, Collins SJ (2018) Prion acute synaptotoxicity is largely driven by protease-resistant PrPSc species. PLoS Pathog 14:e1007214.

Jammal L, Whalley B, Barkai E (2018) Learning induced modulation of the effect of neuroglial transmission on synaptic plasticity J Neurophysiol.

Janz P, Hauser P, Heining K, Nestel S, Kirsch M, Egert U, Haas CA (2018) Position- and Time-Dependent Arc Expression Links Neuronal Activity to Synaptic Plasticity During Epileptogenesis. Frontiers in Cellular Neuroscience 12.

Kurkela JLO, Lipponen A, Kylaheiko I, Astikainen P (2018) Electrophysiological evidence of memory-based detection of auditory regularity violations in anesthetized mice. Sci Rep 8:3027.

Lee S, Kim HB, Hwang ES, Kim ES, Kim SS, Jeon TD, Song MC, Lee JS, Chung MC, Maeng S, Park JH (2018) Antidepressant-like Effects of p-Coumaric Acid on LPS-induced Depressive and Inflammatory Changes in Rats. Exp Neurobiol 27:189-199.

Lensu S, Waselius T, Penttonen M, Nokia MS (2018) Dentate spikes and learning: Disrupting hippocampal function during memory consolidation can improve pattern separation. J Neurophysiol.

McKay S, Ryan TJ, McQueen J, Indersmitten T, Marwick KFM, Hasel P, Kopanitsa MV, Baxter PS, Martel MA, Kind PC, Wyllie DJA, O'Dell TJ, Grant SGN, Hardingham GE, Komiyama NH (2018) The Developmental Shift of NMDA Receptor Composition Proceeds Independently of GluN2 Subunit-Specific GluN2 C-Terminal Sequences. Cell Rep 25:841-851 e844.

Nonomura S, Nishizawa K, Sakai Y, Kawaguchi Y, Kato S, Uchigashima M, Watanabe M, Yamanaka K, Enomoto K, Chiken S, Sano H, Soma S, Yoshida J, Samejima K, Ogawa M, Kobayashi K, Nambu A, Isomura Y, Kimura M (2018) Monitoring and Updating of Action Selection for Goal-Directed Behavior through the Striatal Direct and Indirect Pathways. Neuron 99:1302-1314 e1305.

Piasetzky Y, Bisio M, Kanner S, Goldin M, Olivenboim M, Ben-Jacob E, Hanein Y, Chiappalone M, Barzilai A, Bonifazi P (2018) The emergence of dynamical instantaneous memory in the spontaneous activity of spatially confined neuronal assemblies in vitro. bioRxiv.

Waselius T, Wikgren J, Halkola H, Penttonen M, Nokia MS (2018) Learning by heart: Cardiac cycle reveals an effective time window for learning. J Neurophysiol.

Zhu F, Cizeron M, Qiu Z, Benavides-Piccione R, Kopanitsa MV, Skene NG, Koniaris B, DeFelipe J, Fransen E, Komiyama NH, Grant SGN (2018) Architecture of the Mouse Brain Synaptome. Neuron.

Choi GY, Kim HB, Hwang ES, Lee S, Kim MJ, Choi JY, Lee SO, Kim SS, Park JH (2017) Curcumin Alters Neural Plasticity and Viability of Intact Hippocampal Circuits and Attenuates Behavioral Despair and COX-2 Expression in Chronically Stressed Rats. Mediators Inflamm 2017:6280925.

Effgen GB, Morrison B, 3rd (2017) Electrophysiological and Pathological Characterization of the Period of Heightened Vulnerability to Repetitive Injury in an in Vitro Stretch Model. J Neurotrauma 34:914-924.

Horner AE, McLaughlin CL, Afinowi NO, Bussey TJ, Saksida LM, Komiyama NH, Grant SGN, Kopanitsa MV (2017) Enhanced cognition and dysregulated hippocampal synaptic physiology in mice with a heterozygous deletion of PSD-95. Eur J Neurosci.

Hwang ES, Kim HB, Lee S, Kim MJ, Lee SO, Han SM, Maeng S, Park JH (2017) Loganin enhances long-term potentiation and recovers scopolamine-induced learning and memory impairments. Physiol Behav 171:243-248.

Kasza A, Penke B, Frank Z, Bozso Z, Szegedi V, Hunya A, Nemeth K, Kozma G, Fulop L (2017) Studies for Improving a Rat Model of Alzheimer's Disease: Icv Administration of Well-Characterized beta-Amyloid 1-42 Oligomers Induce Dysfunction in Spatial Memory. Molecules 22.

Kim HB, Lee S, Hwang ES, Maeng S, Park JH (2017) p-Coumaric acid enhances long-term potentiation and recovers scopolamine-induced learning and memory impairments. Biochem Biophys Res Commun 492:493-499.

Miceli S (2017) Modulation of Barrel Cortex Microcircuitry by Serotonin. Department for Cognitive Neuroscience PhD.

Schreurs A, Sabanov V, Balschun D (2017) Distinct Properties of Long-Term Potentiation in the Dentate Gyrus along the Dorsoventral Axis: Influence of Age and Inhibition. Scientific Reports 7:5157.

Shaban H, O'Connor R, Ovsepian SV, Dinan TG, Cryan JF, Schellekens H (2017) Electrophysiological approaches to unravel the neurobiological basis of appetite and satiety: use of the multielectrode array as a screening strategy. In: Drug Discov Today, 2016/09/17 Edition, pp 31-42.

Tanriöver G (2017) Effects of amyloid-beta (Aβ) on homeostatic network plasticity in human iPSC-derived neuronal networks. Pharmazie.

Vardi R, Goldental A, Sheinin A, Sardi S, Kanter I (2017) Fast reversible learning based on neurons functioning as anisotropic multiplex hubs. EPL (Europhysics Letters) 118:46002.

Vogel EW, 3rd, Morales FN, Meaney DF, Bass CR, Morrison B, 3rd (2017) Phosphodiesterase-4 inhibition restored hippocampal long term potentiation after primary blast. Exp Neurol 293:91-100.

Vogel EW, 3rd, Rwema SH, Meaney DF, Bass CR, Morrison B, 3rd (2017) Primary Blast Injury Depressed Hippocampal Long-Term Potentiation through Disruption of Synaptic Proteins. J Neurotrauma 34:1063-1073.

Akhtar MW, Sanz-Blasco S, Dolatabadi N, Parker J, Chon K, Lee MS, Soussou W, McKercher SR, Ambasudhan R, Nakamura T, Lipton SA (2016) Elevated glucose and oligomeric beta-amyloid disrupt synapses via a common pathway of aberrant protein S-nitrosylation. Nat Commun 7:10242.

Broadhead MJ, Horrocks MH, Zhu F, Muresan L, Benavides-Piccione R, DeFelipe J, Fricker D, Kopanitsa MV, Duncan RR, Klenerman D, Komiyama NH, Lee SF, Grant SG (2016) PSD95 nanoclusters are postsynaptic building blocks in hippocampus circuits. Sci Rep 6:24626.

Jammal L, Whalley B, Ghosh S, Lamrecht R, Barkai E (2016) Physiological expression of olfactory discrimination rule learning balances whole-population modulation and circuit stability in the piriform cortex network. Physiol Rep 4.

Knudsen AM (2016) NTNU Cyborg: A study into embodying Neuronal Cultures through Robotic Systems. Department of Engineering Cybernetics.

Kurkela JL, Lipponen A, Hamalainen JA, Naatanen R, Astikainen P (2016) Passive exposure to speech sounds induces long-term memory representations in the auditory cortex of adult rats. Sci Rep 6:38904.

Lee MJ, Chiao CC (2016) Short-term Alteration of Developmental Neural Activity Enhances Neurite Outgrowth of Retinal Explants. Invest Ophthalmol Vis Sci 57:6496-6506.

Carrillo-Reid L, Lopez-Huerta VG, Garcia-Munoz M, Theiss S, Arbuthnott GW (2015) Cell Assembly Signatures Defined by Short-Term Synaptic Plasticity in Cortical Networks. Int J Neural Syst 25:1550026.

Charlesworth P, Cotterill E, Morton A, Grant SG, Eglen SJ (2015) Quantitative differences in developmental profiles of spontaneous activity in cortical and hippocampal cultures. Neural Dev 10:1.

Delattre V, Keller D, Perich M, Markram H, Muller EB (2015) Network-timing-dependent plasticity. Front Cell Neurosci 9:220.

Grosser S (2015) Modulating Hippocampal Output in the Pilocarpine Model of Epilepsy by beta-adrenoceptor Activation. Lebenswissenschaftlichen Fakultät Dr. rer. nat.

Ju H, Dranias MR, Banumurthy G, VanDongen AM (2015) Spatiotemporal memory is an intrinsic property of networks of dissociated cortical neurons. J Neurosci 35:4040-4051.

Menigoz A, Ahmed T, Sabanov V, Philippaert K, Pinto S, Kerselaers S, Segal A, Freichel M, Voets T, Nilius B, Vennekens R, Balschun D (2015) TRPM4-dependent post-synaptic depolarization is essential for the induction of NMDA receptor-dependent LTP in CA1 hippocampal neurons. Pflugers Arch.

Tessadori J, Chiappalone M (2015) Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks.e52341.

Edamura M, Murakami G, Meng H, Itakura M, Shigemoto R, Fukuda A, Nakahara D (2014) Functional Deficiency of MHC Class I Enhances LTP and Abolishes LTD in the Nucleus Accumbens of Mice. PLoS ONE 9:e107099.

Effgen GB, Vogel EW, 3rd, Lynch KA, Lobel A, Hue CD, Meaney DF, Bass CR, Morrison B, 3rd (2014) Isolated primary blast alters neuronal function with minimal cell death in organotypic hippocampal slice cultures. J Neurotrauma 31:1202-1210.

Goldental A, Guberman S, Vardi R, Kanter I (2014) A computational paradigm for dynamic logic-gates in neuronal activity. Front Comput Neurosci 8:52.

Bellistri E, Aguilar J, Brotons-Mas JR, Foffani G, de la Prida LM (2013) Basic properties of somatosensory-evoked responses in the dorsal hippocampus of the rat. J Physiol 591:2667-2686.

Dranias MR, Ju H, Rajaram E, Vandongen AM (2013) Short-term memory in networks of dissociated cortical neurons. J Neurosci 33:1940-1953.

Ryan TJ, Kopanitsa MV, Indersmitten T, Nithianantharajah J, Afinowi NO, Pettit C, Stanford LE, Sprengel R, Saksida LM, Bussey TJ, O'Dell TJ, Grant SG, Komiyama NH (2013) Evolution of GluN2A/B cytoplasmic domains diversified vertebrate synaptic plasticity and behavior. Nat Neurosci 16:25-32.

An S, Yang JW, Sun H, Kilb W, Luhmann HJ (2012) Long-term potentiation in the neonatal rat barrel cortex in vivo. J Neurosci 32:9511-9516.

Balemans MC, Nadif Kasri N, Kopanitsa MV, Afinowi NO, Ramakers G, Peters TA, Beynon AJ, Janssen SM, van Summeren RC, Eeftens JM, Eikelenboom N, Benevento M, Tachibana M, Shinkai Y, Kleefstra T, van Bokhoven H, Van der Zee CE (2012) Hippocampal dysfunction in the Euchromatin histone methyltransferase 1 heterozygous knockout mouse model for Kleefstra syndrome. Hum Mol Genet.

Boehler MD, Leondopulos SS, Wheeler BC, Brewer GJ (2012) Hippocampal networks on reliable patterned substrates. J Neurosci Methods 203:344-353.

Coba MP, Komiyama NH, Nithianantharajah J, Kopanitsa MV, Indersmitten T, Skene NG, Tuck EJ, Fricker DG, Elsegood KA, Stanford LE, Afinowi NO, Saksida LM, Bussey TJ, O'Dell TJ, Grant SG (2012) TNiK is required for postsynaptic and nuclear signaling pathways and cognitive function. J Neurosci 32:13987-13999.

Kaufman M, Corner MA, Ziv NE (2012) Long-term Relationships between Cholinergic Tone, Synchronous Bursting and Synaptic Remodeling. PLoS ONE 7:e40980.

Liu MG, Chen XF, He T, Li Z, Chen J (2012) Use of multi-electrode array recordings in studies of network synaptic plasticity in both time and space. Neurosci Bull 28:409-422.

Newman JP, Zeller-Townson R, Fong MF, Arcot Desai S, Gross RE, Potter SM (2012) Closed-Loop, Multichannel Experimentation Using the Open-Source NeuroRighter Electrophysiology Platform. Front Neural Circuits 6:98.

Chong SA, Benilova I, Shaban H, De Strooper B, Devijver H, Moechars D, Eberle W, Bartic C, Van Leuven F, Callewaert G (2011) Synaptic dysfunction in hippocampus of transgenic mouse models of Alzheimer's disease: a multi-electrode array study. Neurobiol Dis 44:284-291.

Hennig MH, Grady J, van Coppenhagen J, Sernagor E (2011) Age-dependent Homeostatic Plasticity of GABAergic Signaling in Developing Retinal Networks. J Neurosci 31:12159-12164.

Kremer Y, Leger JF, Goodman D, Brette R, Bourdieu L (2011) Late emergence of the vibrissa direction selectivity map in the rat barrel cortex. J Neurosci 31:10689-10700.

Mauceri D, Freitag HE, Oliveira AM, Bengtson CP, Bading H (2011) Nuclear Calcium-VEGFD Signaling Controls Maintenance of Dendrite Arborization Necessary for Memory Formation. Neuron 71:117-130.

Nivet E, Vignes M, Girard SD, Perrisnard C, Barli N, Deveze A, Magnan J, Lante F, Khrestchatisky M, Feron F, Roman FS (2011) Engraftment of human nasal olfactory stem cells restores neuroplasticity in mice with hippocampal lesions. The Journal of Clinical Investigation.

Poil SS, Jansen R, van Aerde K, Timmerman J, Brussaard AB, Mansvelder HD, Linkenkaer-Hansen K (2011) Fast network oscillations in vitro exhibit a slow decay of temporal auto-correlations. Eur J Neurosci 34:394-403.

Verpelli C, Dvoretskova E, Vicidomini C, Rossi F, Chiappalone M, Schoen M, Di Stefano B, Mantegazza R, Broccoli V, Boeckers TM, Dityatev A, Sala C (2011) Importance of shank3 in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapses. J Biol Chem.

Virok DP, Kis Z, Szegedi V, Juhasz G, Zvara A, Jr., Muller G, Levay G, Harsing LG, Rajko R, Penke B, Janka Z, Janaky T, Puskas LG (2011) Functional changes in transcriptomes of the prefrontal cortex and hippocampus in a mouse model of anxiety. Pharmacol Rep 63:348-361.

Boido D, Farisello P, Cesca F, Ferrea E, Valtorta F, Benfenati F, Baldelli P (2010) Cortico-hippocampal hyperexcitability in synapsin I/II/III knockout mice: age-dependency and response to the antiepileptic drug levetiracetam. Neuroscience.

Bologna LL, Nieus T, Tedesco M, Chiappalone M, Benfenati F, Martinoia S (2010) Low-frequency stimulation enhances burst activity in cortical cultures during development. Neuroscience 165:692-704.

Harris CA, Passaro PA, Kemenes I, Kemenes G, O'Shea M (2010) Sensory driven multi-neuronal activity and associative learning monitored in an intact CNS on a multielectrode array. J Neurosci Methods 186:171-178.

Liu JS, Gong XW, Gong HQ, Zhang PM, Liang PJ, Lu QC (2010) [Exploring spatiotemporal patterns of epileptiform discharge in hippocampal slice using multi-electrode arrays.]. Sheng Li Xue Bao 62:163-170.

Mapelli J, Gandolfi D, D'Angelo E (2010) Combinatorial responses controlled by synaptic inhibition in the cerebellum granular layer. J Neurophysiol 103:250-261.

Pegoraro S, Broccard FD, Ruaro ME, Bianchini D, Avossa D, Pastore G, Bisson G, Altafini C, Torre V (2010) Sequential steps underlying neuronal plasticity induced by a transient exposure to gabazine. J Cell Physiol 222:713-728.

Broccard FD, Pegoraro S, Ruaro ME, Altafini C, Torre V (2009) Characterization of the time course of changes of the evoked electrical activity in a model of a chemically-induced neuronal plasticity. BMC Res Notes 2:13.

Fernandez E, Collins MO, Uren RT, Kopanitsa MV, Komiyama NH, Croning MD, Zografos L, Armstrong JD, Choudhary JS, Grant SG (2009) Targeted tandem affinity purification of PSD-95 recovers core postsynaptic complexes and schizophrenia susceptibility proteins. Mol Syst Biol 5:269.

Kerschensteiner D, Morgan JL, Parker ED, Lewis RM, Wong RO (2009) Neurotransmission selectively regulates synapse formation in parallel circuits in vivo. Nature 460:1016-1020.

Paz R, Bauer EP, Pare D (2009) Measuring correlations and interactions among four simultaneously recorded brain regions during learning. J Neurophysiol 101:2507-2515.

Wiegert JS, Hofmann F, Bading H, Bengtson CP (2009) A transcription-dependent increase in miniature EPSC frequency accompanies late-phase plasticity in cultured hippocampal neurons. BMC Neurosci 10:124.

Bakkum DJ, Chao ZC, Potter SM (2008) Long-Term Activity-Dependent Plasticity of Action Potential Propagation Delay and Amplitude in Cortical Networks. PLoS ONE 3:e2088.

Bakkum DJ, Chao ZC, Potter SM (2008) Spatio-temporal electrical stimuli shape behavior of an embodied cortical network in a goal-directed learning task. J Neural Eng 5:310-323.

Haustein MD, Reinert T, Warnatsch A, Englitz B, Dietz B, Robitzki A, Rubsamen R, Milenkovic I (2008) Synaptic transmission and short-term plasticity at the calyx of Held synapse revealed by multielectrode array recordings. J Neurosci Methods.

Lante F, Crouzin N, Vignes M (2008) Unveiling novel forms of hippocampal synaptic plasticity with microelectrode arrays. J Integr Neurosci 7:249-270.

Chiappalone M, Vato A, Berdondini L, Koudelka-Hep M, Martinoia S (2007) Network dynamics and synchronous activity in cultured cortical neurons. Int J Neural Syst 17:87-103.

Lee CM, Sylantyev S, Shyu BC (2007) Short-term synaptic plasticity in layer II/III of the rat anterior cingulate cortex. Brain Res Bull 71:416-427.

Li Y, Zhou W, Li X, Zeng S, Luo Q (2007) Dynamics of learning in cultured neuronal networks with antagonists of glutamate receptors. Biophys J 93:4151-4158.

Madhavan R, Chao ZC, Potter SM (2007) Plasticity of recurring spatiotemporal activity patterns in cortical networks. Phys Biol 4:181-193.

Mapelli J, D'Angelo E (2007) The spatial organization of long-term synaptic plasticity at the input stage of cerebellum. J Neurosci 27:1285-1296.

Volmer R, Prat CM, Le Masson G, Garenne A, Gonzalez-Dunia D (2007) Borna disease virus infection impairs synaptic plasticity. J Virol 81:8833-8837.

Berdondini L, Chiappalone M, vanderWala PD, Imfelda K, deRooija NF, Koudelka-Hepa M, Tedescob M, Martinoiab S, vanPeltd J, LeMassonc G, Garennec A (2006) A microelectrodearray (MEA) integrated with clustering structures for investigating in vitro neurodynamics in confined interconnected sub-populations of neurons. Sensors and Actuators B 114:530–541.

Bjartmar L, Huberman AD, Ullian EM, Renteria RC, Liu X, Xu W, Prezioso J, Susman MW, Stellwagen D, Stokes CC, Cho R, Worley P, Malenka RC, Ball S, Peachey NS, Copenhagen D, Chapman B, Nakamoto M, Barres BA, Perin MS (2006) Neuronal pentraxins mediate synaptic refinement in the developing visual system. J Neurosci 26:6269-6281.

Chiappalone M, Bove M, Vato A, Tedesco M, Martinoia S (2006) Dissociated cortical networks show spontaneously correlated activity patterns during in vitro development. Brain Res 1093:41-53.

Gholmieh G, Soussou W, Han M, Ahuja A, Hsiao MC, Song D, Tanguay AR, Jr., Berger TW (2006) Custom-designed high-density conformal planar multielectrode arrays for brain slice electrophysiology. J Neurosci Methods 152:116-129.

Kim MT, Soussou W, Gholmieh G, Ahuja A, Tanguay A, Berger TW, Brinton RD (2006) 17beta-Estradiol potentiates field excitatory postsynaptic potentials within each subfield of the hippocampus with greatest potentiation of the associational/commissural afferents of CA3. Neuroscience 141:391-406.

Kopanitsa MV, Afinowi NO, Grant SG (2006) Recording long-term potentiation of synaptic transmission by three-dimensional multi-electrode arrays. BMC Neurosci 7:61.

Lante F, de Jesus Ferreira MC, Guiramand J, Recasens M, Vignes M (2006) Low-frequency stimulation induces a new form of LTP, metabotropic glutamate (mGlu5) receptor- and PKA-dependent, in the CA1 area of the rat hippocampus. Hippocampus 16:345-360.

Steidl EM, Neveu E, Bertrand D, Buisson B (2006) The adult rat hippocampal slice revisited with multi-electrode arrays. Brain Res 1096:70-84.

Wagenaar DA, Pine J, Potter SM (2006) Searching for plasticity in dissociated cortical cultures on multi-electrode arrays. J Negat Results Biomed 5:16.

Arnold FJ, Hofmann F, Bengtson CP, Wittmann M, Vanhoutte P, Bading H (2005) Microelectrode array recordings of cultured hippocampal networks reveal a simple model for transcription and protein synthesis-dependent plasticity. J Physiol 564:3-19.

Burrell BD, Sahley CL (2005) Serotonin mediates learning-induced potentiation of excitability. J Neurophysiol 94:4002-4010.

Chao ZC, Bakkum DJ, Wagenaar DA, Potter SM (2005) Effects of random external background stimulation on network synaptic stability after tetanization: a modeling study. Neuroinformatics 3:263-280.

Corner MA, Baker RE, van Pelt J, Wolters PS (2005) Compensatory physiological responses to chronic blockade of amino acid receptors during early development in spontaneously active organotypic cerebral cortex explants cultured in vitro. Prog Brain Res 147:231-248.

Ruaro ME, Bonifazi P, Torre V (2005) Toward the neurocomputer: image processing and pattern recognition with neuronal cultures. IEEE Trans Biomed Eng 52:371-383.

Chen AH, Zhou Y, Gong HQ, Liang PJ (2004) Firing rates and dynamic correlated activities of ganglion cells both contribute to retinal information processing. Brain Res 1017:13-20.

Darbon P, Yvon C, Legrand JC, Streit J (2004) INaP underlies intrinsic spiking and rhythm generation in networks of cultured rat spinal cord neurons. Eur J Neurosci 20:976-988.

Gholmieh G, Courellis S, Dimoka A, Wills JD, LaCoss J, Granacki JJ, Marmarelis V, Berger T (2004) An algorithm for real-time extraction of population EPSP and population spike amplitudes from hippocampal field potential recordings. J Neurosci Methods 136:111-121.

Giugliano M, Darbon P, Arsiero M, Luscher HR, Streit J (2004) Single-neuron discharge properties and network activity in dissociated cultures of neocortex. J Neurophysiol 92:977-996.

Darbon P, Tscherter A, Yvon C, Streit J (2003) Role of the electrogenic Na/K pump in disinhibition-induced bursting in cultured spinal networks. J Neurophysiol 90:3119-3129.

de Weerth S, Ross JD, Prado GR, Choi Y, Allen M, La Placa M (2003) A novel system for Measurememt of electrophysiological Signals associeted with traumatic neuronal injury. 7th International Conference on M Chemical an Biochemical Analysis Systems.

Eytan D, Brenner N, Marom S (2003) Selective adaptation in networks of cortical neurons. J Neurosci 23:9349-9356.

Pedroarena CM, Schwarz C (2003) Efficacy and short-term plasticity at GABAergic synapses between Purkinje and cerebellar nuclei neurons. J Neurophysiol 89:704-715.

Corner MA, van Pelt J, Wolters PS, Baker RE, Nuytinck RH (2002) Physiological effects of sustained blockade of excitatory synaptic transmission on spontaneously active developing neuronal networks--an inquiry into the reciprocal linkage between intrinsic biorhythms and neuroplasticity in early ontogeny. Neurosci Biobehav Rev 26:127-185.

Marom S, Shahaf G (2002) Development, learning and memory in large random networks of cortical neurons: lessons beyond anatomy. Q Rev Biophys 35:63-87.

Egert M (2001) Application of the microelectrode-array (MEA) technology in pharmaceutical drug research. Neurobiologentagung Göttingen:4.

Gholmieh G, Soussou W, Courellis S, Marmarelis V, Berger T, Baudry M (2001) A biosensor for detecting changes in cognitive processing based on nonlinear systems analysis. Biosens Bioelectron 16:491-501.

Shahaf G, Marom S (2001) Learning in networks of cortical neurons. J Neurosci 21:8782-8788.

Egert U, Schlosshauer B, Fennrich S, Nisch W, Fejtl M, Knott T, Muller T, Hammerle H (1998) A novel organotypic long-term culture of the rat hippocampus on substrate-integrated multielectrode arrays. Brain Res Brain Res Protoc 2:229-242.