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Overview

AcadeMEA MEA System

AcadeMEA system MCS single-well microelectrode array

AcadeMEA is a scalable, flexible MEA system designed to make electrophysiology more accessible to labs focused on learning, discovery, and early-stage research. By combining a simplified hardware setup with the proven performance of the MEA2100 platform, AcadeMEA lowers the barrier to entry without sacrificing data quality. Its modular design allows users to start with a streamlined configuration and expand into more advanced Multi Channel Systems solutions over time, ensuring long-term flexibility and protecting your investment as research needs evolve.

The eGG USB Interface

The AcadeMEA eGG USB Interface provides a compact, streamlined connection between the headstage and PC, eliminating unnecessary hardware complexity and making setting up experiments easier for newcomers. With direct USB-C connectivity and integrated data conversion, it enables fast setup and reliable signal transfer in a minimal footprint. Clear LED status indicators provide immediate feedback on system readiness, ensuring efficient operation in day-to-day workflows.

The MEA2100-Mini Headstage

At the core of the system, the MEA2100-Mini headstage delivers high-quality signal acquisition with 24-bit resolution and sampling rates up to 50 kHz per channel. Integrated amplification and software-controlled filtering ensure precise, low-noise recordings across 60 or 120 electrodes. It also records from inside an incubator. Fully compatible with the broader Multi Channel Systems ecosystem, the headstage enables seamless transition to higher-throughput or more advanced MEA platforms as your research progresses.

Need to Scale Up in the Future? Add Headstages Anytime with our IFB-C Board

AcadeMEA makes it easy and cost-effective to scale up to a higher-throughput platform at any time. Our modular design ethos allows you to add additional headstages at any time and even run multiple experiments at the same by adding our IFB-C interface board, which simplifies your setup by connecting multiple Multi Channel Systems platforms through a single, unified interface. Whether you're working with one of our single-well, multiwell, CMOS, or in vivo solutions, the IFB-C allows you to seamlessly switch between configurations without rebuilding your workflow. Start with additional single-well recordings, scale to high-throughput screening, or move between in vitro and in vivo experiments, all using the same core hardware.

Key features with upgrade to complete MEA2100-Mini System with IFB-C:

Real-time signal detection and feedback*
Freely programmable DSP*
Multiple inputs/outputs, including digital, analog, and audio
SuperSpeed USB 3.0 ports

*Available for MEA2100(-Mini), ME2100, and W2100 systems.

Description

Simplified Headstage/Computer Interface

AcadeMEA MEA system single well MCS HBioA MCS HBio_ UTSAphotos_organoids_3_no logo

AcadeMEA replaces the traditional multi-component acquisition chain with a single, streamlined connection via our eGG USB interface, simplifying MEA electrophysiology setup by eliminating the need for multiple intermediate connections. The MEA2100-Mini headstage connects directly to the eGG via a LEMO connector, and the eGG connects to the PC through USB-C.

This simplified architecture lowers the barrier to entry for MEA electrophysiology by minimizing hardware overhead, reducing potential points of failure, and making system setup more intuitive for new users. Fewer components also translate to a more cost-effective solution, making high-quality electrophysiology accessible to a broader range of academic, teaching, and early-stage research labs. At the same time, the system maintains reliable data transfer and acquisition performance, with integrated data conversion and clear LED indicators for system status and readiness.

Includes our MEA2100 Mini-60 or Mini-120 Headstage

MEA_Mini_2100_Metal-1265x1740

AcadeMEA includes the MEA2100-Mini headstage, providing proven, high-performance signal acquisition across 60 or 120 electrodes. The headstage integrates pre-amplification, filtering, and analog-to-digital conversion, delivering 24-bit resolution with sampling rates up to 50 kHz per channel. With a signal input range of ±70 mV, input impedance of 450 MΩ | 10 µF, and low input noise (~0.7 µV RMS), the system ensures high-fidelity recordings suitable for a wide range of electrophysiological applications.

Software-controlled gain and bandwidth allow users to optimize recording conditions for different sample types, while the compact headstage design (186 × 80 × 12 mm, 485 g) supports flexible integration into incubators, benchtop setups, or microscope-based workflows. By using the same headstage platform as advanced MCS systems, AcadeMEA ensures consistency in data quality and enables seamless transition to more complex configurations as experimental needs grow.

Ideal for a Broad Range of Applications

AcadeMEA supports a wide range of in vitro electrophysiology applications, making it a versatile tool for both teaching and research environments:

Neuronal network activity and signaling
Cardiomyocyte electrophysiology
Stem cell-derived models
Organoid and 3D culture studies
Toxicology and long-term studies

Scale up Cost-Effectively When Needed

AcadeMEA is designed as a starting point within the broader Multi Channel Systems ecosystem, allowing users to scale their capabilities without replacing core components. By adding an IFB-C Interface Board, labs can expand their setup to support multiple headstages and run parallel experiments—scaling up to as many as eight simultaneous recordings while maintaining a unified software environment.

Beyond increasing throughput, users can extend their system with specialized headstages and platforms tailored to advanced applications

MEA2100-256 System for high-resolution, 256-channel electrophysiology
Incub8™ Multiwell MEA system for high-throughput screening
Wireless-System for in vivo electrophysiology
ME2100-System for tethered in vivo recordings
IntraCell™ to record intracellular action potentials using laser-based optoporation

This modular upgrade path enables labs to expand functionality incrementally, maximizing flexibility while protecting their initial investment

Products

Documents

Data sheet:

MCS_MEA eGG_Datasheet.pdf

MEAs

120-6wellMEA200/30iR-ITO

6-well microelectrode array for use with the MEA2100-(Mini)-120-System:

TiN electrodes, SiN isolator, contact pads and tracks transparent ITO, with internal reference electrodes, electrode grid is 6x(5x4) (20/well), electrode pitch 200µm (center-center), electrode diameter 30µm. Warranty 6 months.

Mesh MEA

60-3DMEA100/12/40iR-Ti

Three dimensional Microelectrode array:

TiN electrodes, SiN isolator, contact pads and tracks opaque (TiN), with internal reference electrode, electrode grid 8x8, 60 electrodes, electrode spacing 100 µm, electrode diameter 12 µm, electrode height in total 40 µm, warranty: 6 months.

Please note: Due to the delicate etching process involved in 3D electrode production, 60-3DMEAs with one high impedance electrode are still considered top quality.

Read more about our 3D MEAs in this flyer.

60Pedot-pMEA200/30iR-Ti-Au

Microelectrode array, perforated layout, with PEDOT:

PEDOT-CNT electrodes, polyimide isolator, Contact pads Ti-Au and tracks Ti-Au-Ti, with internal reference electrode, electrode grid 8x8, 60 electrodes, electrode spacing 200µm, electrode diameter 30µm, warranty: 6 months.

60-3DMEA200/12/50iR-Ti

Three dimensional Microelectrode array:

TiN electrodes, SiN isolator, contact pads and tracks opaque (TiN), with internal reference electrode, electrode grid 8x8, 60 electrodes, electrode spacing 200 µm, electrode diameter 12 µm, electrode height in total 50 µm, warranty: 6 months.

Please note: Due to the delicate etching process involved in 3D electrode production, 60-3DMEAs with one high impedance electrode are still considered top quality.

Read more about our 3D MEAs in this flyer.

60-3DMEA200/12/80iR-Ti

Three dimensional Microelectrode array:

Please note: Due to the delicate etching process involved in 3D electrode production, 60-3DMEAs with one high impedance electrode are still considered top quality.

Read more about our 3D MEAs in this flyer.

60-3DMEA250/12/100iR-Ti

Three dimensional Microelectrode array:

TiN electrodes, SiN isolator, contact pads and tracks opaque (TiN), with internal reference electrode, electrode grid 8x8, 60 electrodes, electrode spacing 250 µm, electrode diameter 12 µm, electrode height in total 100 µm, warranty: 6 months.

Please note: Due to the delicate etching process involved in 3D electrode production, 60-3DMEAs with one high impedance electrode are still considered top quality.

Read more about our 3D MEAs in this flyer.

60MEA100/10iR-ITO

Standard microelectrode array:

TiN electrodes, SiN isolator, contact pads and tracks transparent (ITO), with 1 internal reference electrode, electrode grid 8x8, 59 recording electrodes, electrode spacing 100µm, electrode diameter 10µm, warranty: 6 months.

60MEA100/10iR-Ti

Standard Microelectrode array:

TiN electrodes, SiN isolator, contact pads and tracks opaque (TiN), with 1 internal reference electrode, electrode grid 8x8, 60 electrodes, electrode spacing 100, electrode diameter 10, warranty: 6 months.

60ThinMEA100/10iR-ITO

Microelectrode array with thin recording field:
180 µm thin recording area, TiN electrodes, SiN isolator, ITO conductive strips, with 1 internal reference electrode, electrode grid 8x8, 59 recording electrodes, electrode spacing 100 µm, electrode diameter 10 µm, warranty: 6 months.

60MEA200/10iR-ITO

Standard Microelectrode array:

TiN electrodes, SiN isolator, contact pads and tracks transparent (ITO), with internal reference electrode, electrode grid 8x8, 60 electrodes, electrode spacing 200µm, electrode diameter 10µm, warranty: 6 months.

60MEA200/10iR-Ti

Standard Microelectrode array:

60MEA200/30iR-ITO

Standard Microelectrode array:

60tMEA200/30iR-ITO

Transparent Microelectrode array:

Transparent TiN electrodes, SiN isolator, contact pads and tracks transparent (ITO), with internal reference electrode, electrode grid 8x8, 60 electrodes, electrode spacing 200µm, electrode diameter 30µm, glass ring 6mm high, warranty: 6 months.

60MEA200/30iR-Ti

Standard Microelectrode array:

60ThinMEA200/30iR-ITO

Microelectrode array with thin recording field:

180µm thin recording area, TiN electrodes, SiN isolator, ITO conductive strips, with internal reference electrode, electrode grid 8x8, 60 electrodes, electrode spacing 200µm, electrode diameter 30µm, warranty: 6 months.

60pMEA200/30iR-Ti

Microelectrode array, perforated layout:

TiN electrodes, Polyimid isolator, contact pads and tracks opaque (TiN on glass carrier), with internal reference electrode, electrode grid 8x8, 60 electrodes, electrode spacing 200µm, electrode diameter 30µm, warranty: 6 months.

60EcoMEA

Low priced microelectrode array:

Gold electrodes and tracks, with internal reference electrode, electrode grid 8x8, 60 electrodes, electrode spacing 700µm, electrode diameter 100µm, warranty: 6 months.

60SquareMEA200/50iR-Ti

Standard microelectrode array:
TiN electrodes (square), SiN isolator, Contact pads and tracks opaque (TiN), With 1 internal reference electrode, Electrode grid 8x8, 59 recording electrodes, Electrode spacing 200 µm, Electrode size 50 µm x 50 µm, Warranty: 6 months.

60PedotMEA200/30iR-Ti-Au

PEDOT-CNT microelectrode array:
PEDOT-CNT electrodes, SiN isolator, Contact pads and tracks opaque (Ti-Au), with 1 internal reference electrode, electrode grid 8x8, recording electrodes, electrode spacing 200 µm, electrode diameter 30 µm, warranty: 6 months.

These electrodes feature some superior properties:

Ideally suited for stimulation
Excellent biocompatibility and cell adhesion
Reproducible low impedance

Please find more information on PEDOT-CNT microelectrode arrays in the flyer.

60MEA500/10iR-Ti

Standard Microelectrode array:

TiN electrodes, SiN isolator, contact pads and tracks opaque (TiN), with internal reference electrode, electrode grid 6x10, 60 electrodes, electrode spacing 500µm, electrode diameter 10µm, warranty: 6 months.

60MEA500/30iR-Ti

Standard Microelectrode array:

60pMEA100/30iR-Ti

Microelectrode array, perforated layout:

TiN electrodes, Polyimid isolator, contact pads and tracks opaque (TiN on glass carrier), with internal reference electrode, electrode grid 6x10, 60 electrodes, electrode spacing 100µm, electrode diameter 30µm, warranty: 6 months.

60HDMEA30/10iR-ITO

High dense Microelectrode array:

Double recording field (500µm in-between fields), TiN electrodes, SiN isolator, contact pads and tracks transparent (ITO), with internal reference electrode, electrode grid 2x(5x6), 60 electrodes, electrode spacing 30µm, electrode diameter 10µm, warranty: 6 months.

60ThinMEA30/10iR-ITO

Microelectrode array with thin recording field:

180µm thin recording area, TiN electrodes, SiN isolator, ITO conductive strips, with internal reference electrode, electrode grid 2x(5x6), 60 electrodes, electrode spacing 30, electrode diameter 10, warranty: 6 months.

60HexaMEA40/10iR-ITO

Microelectrode array, hexagonal layout:

TiN electrodes, SiN isolator, contact pads and tracks transparent (ITO), with internal reference electrode, electrode grid hexagonal, 60 electrodes, electrode spacing 40µm, electrode diameter 10µm, warranty: 6 months.

60-6wellMEA200/30iR-Ti

Microelectrode array with 6 recording areas, circular layout:

Tin electrodes, SiN isolator, contact pads and tracks opaque (TiN), with internal reference electrode in each area, electrode grid 3x3 in each area, 54 electrodes, electrode spacing 200µm, electrode diameter 30µm, warranty: 6 months.

60-4QMEA1000iR-Ti

4 quadrants microelectrode array:

TiN electrodes, SiN isolator, contact pads and tracks opaque (TiN), with internal reference electrode, electrode grid 4x (1x4 + 1x5 + 1x4) + center line 1x7, 60 electrodes, electrode spacing 200µm inside the quadrants; 1000µm between the quadrants, electrode diameter 30µm, warranty: 6 months.

120MEA30/10iR-ITO

Microelectrode array for MEA2100-HS120:

TiN electrodes, SiN isolator, contact pads and tracks transparent (ITO), with 4 internal reference electrodes, electrode grid 12x12, 120 recording electrodes, electrode spacing 30µm, electrode diameter 10µm, warranty: 6 months

120MEA100/30iR-ITO

Microelectrode array for MEA2100-HS120:

TiN electrodes, SiN isolator, contact pads and tracks transparent (ITO), with 4 internal reference electrodes, electrode grid 12x12, 120 recording electrodes, electrode spacing 100µm, electrode diameter 30µm, warranty: 6 months

120tMEA100/30iR-ITO

Transparent Microelectrode array:

Transparent TiN electrodes, SiN isolator, contact pads and tracks transparent (ITO), with 4 internal reference electrodes, electrode grid 12x12, 120 electrodes, electrode spacing 100µm, electrode diameter 30µm, without ring, warranty: 6 months.

120MEA200/30iR-Ti

Microelectrode array for MEA2100-HS120:

TiN electrodes, SiN isolator, contact pads and tracks opaque (Ti), with internal reference electrodes, electrode grid 12x12, 124 electrodes, electrode spacing 200µm, electrode diameter 30µm, warranty: 6 months.

120MEA1000-1500/30iR-Ti

Microelectrode array for MEA2100-HS120:

TiN electrodes, SiN isolator, contact pads and tracks opaque (Ti), with 4 internal reference electrodes, electrode grid 12x10, 120 electrodes, electrode spacing 1000 µm vertical, 1500 µm horizontal, electrode diameter 30 µm, with plastic ring with thread, warranty: 6 months.

120pMEA100/30iR-Ti

Perforated microelectrode array for MEA2100-HS120:

TiN electrodes, polyimid isolator, contact pads and tracks opaque (Ti on glass carrier), with 4 internal reference electrode, electrode grid 12x12, 120 recording electrodes, electrode spacing 100µm, electrode diameter 30µm, warranty: 6 months.

120pMEA200/30iR-Ti

Perforated microelectrode array for MEA2100-HS120:

TiN electrodes, polyimid isolator, contact pads and tracks opaque (Ti on glass carrier), with 4 internal reference electrode, electrode grid 12x12, 120 recording electrodes, electrode spacing 200µm, electrode diameter 30µm, warranty: 6 months.

120-3DMEA250/12/100iR-Ti

Microelectrode array for MEA2100-HS120:

Three dimensional Microelectrode array with TiN electrodes, SiN isolator, contact pads and tracks opaque (TiN), with internal reference electrode, electrode grid 12x12, 120 electrodes, electrode spacing 250 µm, electrode diameter 12 µm, electrode height in total 100 µm, warranty: 6 months.

Please note: Due to the delicate etching process involved in 3D electrode production, 120-3DMEAs with two high impedance electrodes are still considered top quality.

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AcadeMEA Single-well MEA System

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AcadeMEA MEA System

The eGG USB Interface

The MEA2100-Mini Headstage

Need to Scale Up in the Future? Add Headstages Anytime with our IFB-C Board

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